DK335083A - Fremgangsmaade til fremstilling af imidazobenzodiazepiner eller farmaceutisk acceptable syreadditionssalte deraf - Google Patents

Fremgangsmaade til fremstilling af imidazobenzodiazepiner eller farmaceutisk acceptable syreadditionssalte deraf Download PDF

Info

Publication number
DK335083A
DK335083A DK335083A DK335083A DK335083A DK 335083 A DK335083 A DK 335083A DK 335083 A DK335083 A DK 335083A DK 335083 A DK335083 A DK 335083A DK 335083 A DK335083 A DK 335083A
Authority
DK
Denmark
Prior art keywords
lower alkyl
optionally substituted
imidazobenzodiazepines
acid addition
addition salts
Prior art date
Application number
DK335083A
Other languages
Danish (da)
English (en)
Other versions
DK335083D0 (da
Inventor
Walter Hunkeler
Emilio Kyburz
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of DK335083D0 publication Critical patent/DK335083D0/da
Publication of DK335083A publication Critical patent/DK335083A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D265/24—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in positions 2 and 4
    • C07D265/26—Two oxygen atoms, e.g. isatoic anhydride
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/38—Oxygen atoms in positions 2 and 3, e.g. isatin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pyrrole Compounds (AREA)
DK335083A 1982-07-21 1983-07-20 Fremgangsmaade til fremstilling af imidazobenzodiazepiner eller farmaceutisk acceptable syreadditionssalte deraf DK335083A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH446082 1982-07-21

Publications (2)

Publication Number Publication Date
DK335083D0 DK335083D0 (da) 1983-07-20
DK335083A true DK335083A (da) 1984-01-22

Family

ID=4276529

Family Applications (1)

Application Number Title Priority Date Filing Date
DK335083A DK335083A (da) 1982-07-21 1983-07-20 Fremgangsmaade til fremstilling af imidazobenzodiazepiner eller farmaceutisk acceptable syreadditionssalte deraf

Country Status (25)

Country Link
US (1) US4489003A (fr)
EP (1) EP0100906B1 (fr)
JP (1) JPS5933286A (fr)
KR (1) KR840005836A (fr)
AT (1) ATE27160T1 (fr)
AU (1) AU560286B2 (fr)
BR (1) BR8303898A (fr)
CA (1) CA1202969A (fr)
CS (1) CS246063B2 (fr)
CU (1) CU21554A3 (fr)
DE (1) DE3371516D1 (fr)
DK (1) DK335083A (fr)
ES (4) ES524280A0 (fr)
FI (1) FI832654A (fr)
GR (1) GR79322B (fr)
HU (1) HU189719B (fr)
IE (1) IE56121B1 (fr)
IL (1) IL69242A (fr)
MC (1) MC1528A1 (fr)
NO (1) NO832633L (fr)
NZ (1) NZ204912A (fr)
PH (1) PH18980A (fr)
PT (1) PT77063B (fr)
ZA (1) ZA835147B (fr)
ZW (1) ZW14383A1 (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CS249148B2 (en) * 1984-01-19 1987-03-12 Hoffmann La Roche Method of new imidazodiazepine's derivatives production
CA1259612A (fr) * 1985-02-28 1989-09-19 Emilio Kyburz Derives d'imidazodiazepine
DK174086D0 (da) * 1986-04-16 1986-04-16 Ferrosan As Nye benzodiazepinderivater samt fremgangsmaade til fremstilling af samme
GB8720414D0 (en) * 1987-08-28 1987-10-07 Roussel Lab Ltd Chemical compounds
CA2015336A1 (fr) * 1989-05-19 1990-11-19 F. Hoffmann-La Roche Ag Imidazodiazepines pour le traitement des symptomes neurologiques
IE910939A1 (en) * 1990-04-13 1991-10-23 Neurosearch As Use of benzodiazepine compounds
GB9911152D0 (en) * 1999-05-14 1999-07-14 Glaxo Group Ltd Short-acting benzodiazepines
US7160880B1 (en) 1999-05-14 2007-01-09 Cenes Limited Short-acting benzodiazepines
WO2007018660A2 (fr) * 2005-05-16 2007-02-15 Wisys Technology Foundation, Inc. Agents gabaergiques utilises dans le traitement de troubles de la memoire
KR20150081370A (ko) 2006-07-10 2015-07-13 파이온 유케이 리미티드 속효형 벤조디아제핀 염 및 이의 중합체 형태
US20090054412A1 (en) * 2007-08-20 2009-02-26 John Alan Kemp Treatment of Sleep Disorders
EP2190435B1 (fr) * 2007-08-20 2018-05-30 Evotec International GmbH Traitement de troubles du sommeil
EP2450039A1 (fr) 2010-11-08 2012-05-09 PAION UK Ltd. Régime de dosage permettant la sédation avec CNS 7056 (Remimazolam)
AR094963A1 (es) 2013-03-04 2015-09-09 Ono Pharmaceutical Co Reacción de oxidación excelente en el índice de conversión
EP4069369A4 (fr) * 2019-12-06 2024-02-14 Schrödinger, Inc. Composés cycliques et leurs procédés d'utilisation

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1143728A (fr) * 1979-10-04 1983-03-29 Max Gerecke Derives d'imidazodiazepine
CA1184175A (fr) * 1981-02-27 1985-03-19 Walter Hunkeler Imidazodiazepines
CA1185602A (fr) * 1981-02-27 1985-04-16 Emilio Kyburz Imidazodiazepines
US4352817A (en) * 1981-02-27 1982-10-05 Hoffmann-La Roche Inc. Imidazo-diazepines and their use
CA1173441A (fr) * 1981-02-27 1984-08-28 Hoffmann-La Roche Limited Imidazodiazepines

Also Published As

Publication number Publication date
EP0100906B1 (fr) 1987-05-13
ES530673A0 (es) 1985-05-01
ZW14383A1 (en) 1985-01-23
ES8504805A1 (es) 1985-05-01
EP0100906A2 (fr) 1984-02-22
PH18980A (en) 1985-11-29
DE3371516D1 (de) 1987-06-19
US4489003A (en) 1984-12-18
HU189719B (en) 1986-07-28
CS246063B2 (en) 1986-10-16
ES530671A0 (es) 1985-05-16
ZA835147B (en) 1984-03-28
FI832654A0 (fi) 1983-07-21
NO832633L (no) 1984-01-23
ES530672A0 (es) 1985-05-16
KR840005836A (ko) 1984-11-19
PT77063B (en) 1986-07-15
BR8303898A (pt) 1984-04-10
AU1688883A (en) 1984-01-26
IE56121B1 (en) 1991-04-24
JPS5933286A (ja) 1984-02-23
CS541983A2 (en) 1985-12-16
DK335083D0 (da) 1983-07-20
CU21554A3 (en) 1987-06-09
EP0100906A3 (en) 1984-08-22
IL69242A (en) 1986-09-30
FI832654A (fi) 1984-01-22
ES8500945A1 (es) 1984-11-16
IL69242A0 (en) 1983-11-30
CA1202969A (fr) 1986-04-08
ES524280A0 (es) 1984-11-16
AU560286B2 (en) 1987-04-02
MC1528A1 (fr) 1984-04-13
GR79322B (fr) 1984-10-22
IE831696L (en) 1984-01-21
PT77063A (en) 1983-08-01
NZ204912A (en) 1986-10-08
ES8505180A1 (es) 1985-05-16
ATE27160T1 (de) 1987-05-15
ES8505179A1 (es) 1985-05-16

Similar Documents

Publication Publication Date Title
DK335083A (da) Fremgangsmaade til fremstilling af imidazobenzodiazepiner eller farmaceutisk acceptable syreadditionssalte deraf
DK452980A (da) Fremgangsmaade til fremstilling af sekundaere aminer
DK87182A (da) Fremgangsmaade til fremstilling af imidazodiazepiner eller farmaceutisk acceptable syreadditionssalte deraf
DK420682A (da) Fremgangsmaade til fremstilling af triazoloquinazoloner eller salte deraf
ES2063157T3 (es) Nuevos derivados del indol, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.
DK167580A (da) Fremgangsmaade til fremstilling af oxazolin- og thiazolinderivater

Legal Events

Date Code Title Description
AHB Application shelved due to non-payment
AHB Application shelved due to non-payment