ES530672A0 - Un procedimiento para la preparacion de imidazobenzodiacepinas - Google Patents

Un procedimiento para la preparacion de imidazobenzodiacepinas

Info

Publication number
ES530672A0
ES530672A0 ES530672A ES530672A ES530672A0 ES 530672 A0 ES530672 A0 ES 530672A0 ES 530672 A ES530672 A ES 530672A ES 530672 A ES530672 A ES 530672A ES 530672 A0 ES530672 A0 ES 530672A0
Authority
ES
Spain
Prior art keywords
lower alkyl
optionally substituted
propenylene
dimethylene
trimethylene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES530672A
Other languages
English (en)
Other versions
ES8505180A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of ES530672A0 publication Critical patent/ES530672A0/es
Publication of ES8505180A1 publication Critical patent/ES8505180A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D265/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/041,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/121,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/141,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D265/241,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in positions 2 and 4
    • C07D265/26Two oxygen atoms, e.g. isatoic anhydride
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02Muscle relaxants, e.g. for tetanus or cramps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32Oxygen atoms
    • C07D209/38Oxygen atoms in positions 2 and 3, e.g. isatin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pyrrole Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
ES530672A 1982-07-21 1984-03-16 Un procedimiento para la preparacion de imidazobenzodiacepinas Expired ES8505180A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH446082 1982-07-21

Publications (2)

Publication Number Publication Date
ES530672A0 true ES530672A0 (es) 1985-05-16
ES8505180A1 ES8505180A1 (es) 1985-05-16

Family

ID=4276529

Family Applications (4)

Application Number Title Priority Date Filing Date
ES524280A Granted ES524280A0 (es) 1982-07-21 1983-07-20 "un procedimiento para la preparacion de imidazobenzodiacepinas"
ES530673A Granted ES530673A0 (es) 1982-07-21 1984-03-16 Un procedimiento para la preparacion de imidazobenzodiacepinas
ES530672A Expired ES8505180A1 (es) 1982-07-21 1984-03-16 Un procedimiento para la preparacion de imidazobenzodiacepinas
ES530671A Expired ES8505179A1 (es) 1982-07-21 1984-03-16 Un procedimiento para la preparacion de imidazobenzodiacepinas

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES524280A Granted ES524280A0 (es) 1982-07-21 1983-07-20 "un procedimiento para la preparacion de imidazobenzodiacepinas"
ES530673A Granted ES530673A0 (es) 1982-07-21 1984-03-16 Un procedimiento para la preparacion de imidazobenzodiacepinas

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES530671A Expired ES8505179A1 (es) 1982-07-21 1984-03-16 Un procedimiento para la preparacion de imidazobenzodiacepinas

Country Status (25)

Country Link
US (1) US4489003A (es)
EP (1) EP0100906B1 (es)
JP (1) JPS5933286A (es)
KR (1) KR840005836A (es)
AT (1) ATE27160T1 (es)
AU (1) AU560286B2 (es)
BR (1) BR8303898A (es)
CA (1) CA1202969A (es)
CS (1) CS246063B2 (es)
CU (1) CU21554A3 (es)
DE (1) DE3371516D1 (es)
DK (1) DK335083A (es)
ES (4) ES524280A0 (es)
FI (1) FI832654A (es)
GR (1) GR79322B (es)
HU (1) HU189719B (es)
IE (1) IE56121B1 (es)
IL (1) IL69242A (es)
MC (1) MC1528A1 (es)
NO (1) NO832633L (es)
NZ (1) NZ204912A (es)
PH (1) PH18980A (es)
PT (1) PT77063B (es)
ZA (1) ZA835147B (es)
ZW (1) ZW14383A1 (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CS249146B2 (en) * 1984-01-19 1987-03-12 Hoffmann La Roche Method of new imidazodiazepine's derivatives production
CA1259612A (en) * 1985-02-28 1989-09-19 Emilio Kyburz Imidazodiazepine derivatives
DK174086D0 (da) * 1986-04-16 1986-04-16 Ferrosan As Nye benzodiazepinderivater samt fremgangsmaade til fremstilling af samme
GB8720414D0 (en) * 1987-08-28 1987-10-07 Roussel Lab Ltd Chemical compounds
CA2015336A1 (en) * 1989-05-19 1990-11-19 F. Hoffmann-La Roche Ag Imidazodiazepines for the treatment of neurological symptoms
IE910939A1 (en) * 1990-04-13 1991-10-23 Neurosearch As Use of benzodiazepine compounds
US7160880B1 (en) 1999-05-14 2007-01-09 Cenes Limited Short-acting benzodiazepines
GB9911152D0 (en) * 1999-05-14 1999-07-14 Glaxo Group Ltd Short-acting benzodiazepines
AU2006276998A1 (en) * 2005-05-16 2007-02-15 Wisys Technology Foundation, Inc. Gabaergic agents to treat memory deficits
PL2081921T3 (pl) 2006-07-10 2011-03-31 Paion Uk Ltd Krótko działające sole benzodiazepiny i ich formy polimorficzne
BRPI0815579A2 (pt) 2007-08-20 2015-02-18 Evotec Neurosciences Gmbh Tratamento de distúrbio do sono
US20090054412A1 (en) * 2007-08-20 2009-02-26 John Alan Kemp Treatment of Sleep Disorders
EP2450039A1 (en) 2010-11-08 2012-05-09 PAION UK Ltd. Dosing regimen for sedation with CNS 7056 (Remimazolam)
AR094963A1 (es) 2013-03-04 2015-09-09 Ono Pharmaceutical Co Reacción de oxidación excelente en el índice de conversión
EP4069369A4 (en) * 2019-12-06 2024-02-14 Schroedinger Inc CYCLIC COMPOUNDS AND METHODS OF USE THEREOF

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1143728A (en) * 1979-10-04 1983-03-29 Max Gerecke Imidazodiazepine derivatives
CA1185602A (en) * 1981-02-27 1985-04-16 Emilio Kyburz Imidazodiazepines
CA1184175A (en) * 1981-02-27 1985-03-19 Walter Hunkeler Imidazodiazepines
US4352817A (en) * 1981-02-27 1982-10-05 Hoffmann-La Roche Inc. Imidazo-diazepines and their use
CA1173441A (en) * 1981-02-27 1984-08-28 Hoffmann-La Roche Limited Imidazodiazepines

Also Published As

Publication number Publication date
CA1202969A (en) 1986-04-08
DK335083A (da) 1984-01-22
IL69242A (en) 1986-09-30
EP0100906B1 (de) 1987-05-13
NZ204912A (en) 1986-10-08
GR79322B (es) 1984-10-22
US4489003A (en) 1984-12-18
BR8303898A (pt) 1984-04-10
ES8500945A1 (es) 1984-11-16
ES524280A0 (es) 1984-11-16
AU1688883A (en) 1984-01-26
CS541983A2 (en) 1985-12-16
CU21554A3 (en) 1987-06-09
EP0100906A3 (en) 1984-08-22
PT77063A (en) 1983-08-01
IE56121B1 (en) 1991-04-24
AU560286B2 (en) 1987-04-02
ATE27160T1 (de) 1987-05-15
ES8504805A1 (es) 1985-05-01
EP0100906A2 (de) 1984-02-22
FI832654A (fi) 1984-01-22
ZW14383A1 (en) 1985-01-23
DK335083D0 (da) 1983-07-20
ES530673A0 (es) 1985-05-01
ZA835147B (en) 1984-03-28
CS246063B2 (en) 1986-10-16
DE3371516D1 (de) 1987-06-19
KR840005836A (ko) 1984-11-19
JPS5933286A (ja) 1984-02-23
PH18980A (en) 1985-11-29
NO832633L (no) 1984-01-23
IL69242A0 (en) 1983-11-30
IE831696L (en) 1984-01-21
MC1528A1 (fr) 1984-04-13
ES530671A0 (es) 1985-05-16
FI832654A0 (fi) 1983-07-21
ES8505180A1 (es) 1985-05-16
HU189719B (en) 1986-07-28
ES8505179A1 (es) 1985-05-16
PT77063B (en) 1986-07-15

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