ZW14383A1 - Imidazobenzodiazepines - Google Patents

Imidazobenzodiazepines

Info

Publication number
ZW14383A1
ZW14383A1 ZW143/83A ZW14383A ZW14383A1 ZW 14383 A1 ZW14383 A1 ZW 14383A1 ZW 143/83 A ZW143/83 A ZW 143/83A ZW 14383 A ZW14383 A ZW 14383A ZW 14383 A1 ZW14383 A1 ZW 14383A1
Authority
ZW
Zimbabwe
Prior art keywords
lower alkyl
optionally substituted
propenylene
dimethylene
trimethylene
Prior art date
Application number
ZW143/83A
Other languages
English (en)
Inventor
Hunkeler Walter
Kyburz Emilio
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of ZW14383A1 publication Critical patent/ZW14383A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D265/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/041,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/121,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/141,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D265/241,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in positions 2 and 4
    • C07D265/26Two oxygen atoms, e.g. isatoic anhydride
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02Muscle relaxants, e.g. for tetanus or cramps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32Oxygen atoms
    • C07D209/38Oxygen atoms in positions 2 and 3, e.g. isatin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pyrrole Compounds (AREA)
ZW143/83A 1982-07-21 1983-06-24 Imidazobenzodiazepines ZW14383A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH446082 1982-07-21

Publications (1)

Publication Number Publication Date
ZW14383A1 true ZW14383A1 (en) 1985-01-23

Family

ID=4276529

Family Applications (1)

Application Number Title Priority Date Filing Date
ZW143/83A ZW14383A1 (en) 1982-07-21 1983-06-24 Imidazobenzodiazepines

Country Status (25)

Country Link
US (1) US4489003A (fr)
EP (1) EP0100906B1 (fr)
JP (1) JPS5933286A (fr)
KR (1) KR840005836A (fr)
AT (1) ATE27160T1 (fr)
AU (1) AU560286B2 (fr)
BR (1) BR8303898A (fr)
CA (1) CA1202969A (fr)
CS (1) CS246063B2 (fr)
CU (1) CU21554A3 (fr)
DE (1) DE3371516D1 (fr)
DK (1) DK335083A (fr)
ES (4) ES8500945A1 (fr)
FI (1) FI832654A (fr)
GR (1) GR79322B (fr)
HU (1) HU189719B (fr)
IE (1) IE56121B1 (fr)
IL (1) IL69242A (fr)
MC (1) MC1528A1 (fr)
NO (1) NO832633L (fr)
NZ (1) NZ204912A (fr)
PH (1) PH18980A (fr)
PT (1) PT77063B (fr)
ZA (1) ZA835147B (fr)
ZW (1) ZW14383A1 (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL74070A (en) * 1984-01-19 1988-12-30 Hoffmann La Roche Imidazodiazepine derivatives,their manufacture and pharmaceutical compositions containing them
CA1259612A (fr) * 1985-02-28 1989-09-19 Emilio Kyburz Derives d'imidazodiazepine
DK174086D0 (da) * 1986-04-16 1986-04-16 Ferrosan As Nye benzodiazepinderivater samt fremgangsmaade til fremstilling af samme
GB8720414D0 (en) * 1987-08-28 1987-10-07 Roussel Lab Ltd Chemical compounds
CA2015336A1 (fr) * 1989-05-19 1990-11-19 F. Hoffmann-La Roche Ag Imidazodiazepines pour le traitement des symptomes neurologiques
IE910939A1 (en) * 1990-04-13 1991-10-23 Neurosearch As Use of benzodiazepine compounds
GB9911152D0 (en) * 1999-05-14 1999-07-14 Glaxo Group Ltd Short-acting benzodiazepines
US7160880B1 (en) 1999-05-14 2007-01-09 Cenes Limited Short-acting benzodiazepines
CA2607226A1 (fr) * 2005-05-16 2007-02-15 Wisys Technology Foundation, Inc. Agents gabaergiques utilises dans le traitement de troubles de la memoire
CA2657347C (fr) 2006-07-10 2014-11-18 Paion Uk Limited Sels de benzodiazepine et leurs formes polymorphes a action breve
WO2009024325A2 (fr) * 2007-08-20 2009-02-26 Evotec Neurosciences Gmbh Traitement de troubles du sommeil
US20090054412A1 (en) * 2007-08-20 2009-02-26 John Alan Kemp Treatment of Sleep Disorders
EP2450039A1 (fr) 2010-11-08 2012-05-09 PAION UK Ltd. Régime de dosage permettant la sédation avec CNS 7056 (Remimazolam)
AR094963A1 (es) 2013-03-04 2015-09-09 Ono Pharmaceutical Co Reacción de oxidación excelente en el índice de conversión
EP4069369A4 (fr) * 2019-12-06 2024-02-14 Schrödinger, Inc. Composés cycliques et leurs procédés d'utilisation

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1143728A (fr) * 1979-10-04 1983-03-29 Max Gerecke Derives d'imidazodiazepine
CA1184175A (fr) * 1981-02-27 1985-03-19 Walter Hunkeler Imidazodiazepines
US4352817A (en) * 1981-02-27 1982-10-05 Hoffmann-La Roche Inc. Imidazo-diazepines and their use
CA1173441A (fr) * 1981-02-27 1984-08-28 Hoffmann-La Roche Limited Imidazodiazepines
CA1185602A (fr) * 1981-02-27 1985-04-16 Emilio Kyburz Imidazodiazepines

Also Published As

Publication number Publication date
ES530671A0 (es) 1985-05-16
PT77063B (en) 1986-07-15
JPS5933286A (ja) 1984-02-23
DK335083D0 (da) 1983-07-20
DK335083A (da) 1984-01-22
DE3371516D1 (de) 1987-06-19
IL69242A (en) 1986-09-30
NZ204912A (en) 1986-10-08
BR8303898A (pt) 1984-04-10
ES524280A0 (es) 1984-11-16
IE831696L (en) 1984-01-21
PT77063A (en) 1983-08-01
ATE27160T1 (de) 1987-05-15
IL69242A0 (en) 1983-11-30
NO832633L (no) 1984-01-23
CS541983A2 (en) 1985-12-16
EP0100906B1 (fr) 1987-05-13
ES8505179A1 (es) 1985-05-16
ES530673A0 (es) 1985-05-01
KR840005836A (ko) 1984-11-19
EP0100906A2 (fr) 1984-02-22
MC1528A1 (fr) 1984-04-13
PH18980A (en) 1985-11-29
ES8504805A1 (es) 1985-05-01
FI832654A (fi) 1984-01-22
ZA835147B (en) 1984-03-28
CA1202969A (fr) 1986-04-08
ES8505180A1 (es) 1985-05-16
ES530672A0 (es) 1985-05-16
IE56121B1 (en) 1991-04-24
AU1688883A (en) 1984-01-26
AU560286B2 (en) 1987-04-02
CU21554A3 (en) 1987-06-09
EP0100906A3 (en) 1984-08-22
US4489003A (en) 1984-12-18
FI832654A0 (fi) 1983-07-21
HU189719B (en) 1986-07-28
GR79322B (fr) 1984-10-22
CS246063B2 (en) 1986-10-16
ES8500945A1 (es) 1984-11-16

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