DK3330264T3 - Pyridin substitueret 2-aminopyridin proteinkinase-inhibitorkrystal - Google Patents
Pyridin substitueret 2-aminopyridin proteinkinase-inhibitorkrystal Download PDFInfo
- Publication number
- DK3330264T3 DK3330264T3 DK16829879.2T DK16829879T DK3330264T3 DK 3330264 T3 DK3330264 T3 DK 3330264T3 DK 16829879 T DK16829879 T DK 16829879T DK 3330264 T3 DK3330264 T3 DK 3330264T3
- Authority
- DK
- Denmark
- Prior art keywords
- substitueret
- inhibitorkrystal
- proteinkinase
- aminopyridin
- pyridin
- Prior art date
Links
- ICSNLGPSRYBMBD-UHFFFAOYSA-N 2-aminopyridine Chemical compound NC1=CC=CC=N1 ICSNLGPSRYBMBD-UHFFFAOYSA-N 0.000 title 1
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510458524 | 2015-07-30 | ||
| PCT/CN2016/092269 WO2017016514A1 (zh) | 2015-07-30 | 2016-07-29 | 吡啶取代的2-氨基吡啶类蛋白激酶抑制剂的结晶 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3330264T3 true DK3330264T3 (en) | 2020-06-02 |
Family
ID=57884126
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK16829879.2T DK3330264T3 (en) | 2015-07-30 | 2016-07-29 | Pyridin substitueret 2-aminopyridin proteinkinase-inhibitorkrystal |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US10385038B2 (da) |
| EP (1) | EP3330264B1 (da) |
| JP (1) | JP6513294B2 (da) |
| CN (3) | CN110330483A (da) |
| DK (1) | DK3330264T3 (da) |
| HK (1) | HK1250368B (da) |
| HU (1) | HUE050352T2 (da) |
| TW (1) | TWI707848B (da) |
| WO (1) | WO2017016514A1 (da) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016015676A1 (zh) * | 2014-07-31 | 2016-02-04 | 正大天晴药业集团股份有限公司 | 吡啶取代的2-氨基吡啶类蛋白激酶抑制剂 |
| CN114173785A (zh) * | 2019-08-01 | 2022-03-11 | 正大天晴药业集团股份有限公司 | 用于治疗非小细胞肺癌的氨基吡啶衍生物 |
| CN115484955A (zh) * | 2020-04-30 | 2022-12-16 | 正大天晴药业集团股份有限公司 | 用于治疗met基因异常疾病的氨基吡啶衍生物 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008510792A (ja) | 2004-08-26 | 2008-04-10 | ファイザー・インク | タンパク質チロシンキナーゼ阻害剤としてのアミノヘテロアリール化合物 |
| PT2952510T (pt) | 2013-02-02 | 2019-04-16 | Centaurus Biopharma Co Ltd | Inibidor de proteína-cinase de 2-aminopiridina substituída |
| CN103965161A (zh) * | 2013-02-02 | 2014-08-06 | 正大天晴药业集团股份有限公司 | 取代的2-氨基吡啶类蛋白激酶抑制剂 |
| WO2016015676A1 (zh) * | 2014-07-31 | 2016-02-04 | 正大天晴药业集团股份有限公司 | 吡啶取代的2-氨基吡啶类蛋白激酶抑制剂 |
| KR102203025B1 (ko) * | 2014-08-06 | 2021-01-14 | 엘지이노텍 주식회사 | 탄화규소 에피 웨이퍼 제조 방법 |
-
2016
- 2016-07-29 EP EP16829879.2A patent/EP3330264B1/en active Active
- 2016-07-29 CN CN201910731905.9A patent/CN110330483A/zh active Pending
- 2016-07-29 WO PCT/CN2016/092269 patent/WO2017016514A1/zh active Application Filing
- 2016-07-29 US US15/749,075 patent/US10385038B2/en active Active
- 2016-07-29 CN CN201910731904.4A patent/CN110283161B/zh active Active
- 2016-07-29 DK DK16829879.2T patent/DK3330264T3/da active
- 2016-07-29 CN CN201680043892.0A patent/CN107949560B/zh active Active
- 2016-07-29 HU HUE16829879A patent/HUE050352T2/hu unknown
- 2016-07-29 JP JP2018524523A patent/JP6513294B2/ja active Active
- 2016-08-01 TW TW105124294A patent/TWI707848B/zh active
-
2018
- 2018-07-31 HK HK18109836.9A patent/HK1250368B/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HK1250368B (zh) | 2020-05-22 |
| CN110283161A (zh) | 2019-09-27 |
| WO2017016514A1 (zh) | 2017-02-02 |
| TWI707848B (zh) | 2020-10-21 |
| US20180244649A1 (en) | 2018-08-30 |
| EP3330264A4 (en) | 2019-01-09 |
| JP6513294B2 (ja) | 2019-05-15 |
| TW201704226A (zh) | 2017-02-01 |
| EP3330264A1 (en) | 2018-06-06 |
| CN110330483A (zh) | 2019-10-15 |
| CN107949560B (zh) | 2019-08-16 |
| JP2018522067A (ja) | 2018-08-09 |
| EP3330264B1 (en) | 2020-05-06 |
| US10385038B2 (en) | 2019-08-20 |
| CN110283161B (zh) | 2021-09-03 |
| CN107949560A (zh) | 2018-04-20 |
| HUE050352T2 (hu) | 2020-11-30 |
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