CN114173785A - 用于治疗非小细胞肺癌的氨基吡啶衍生物 - Google Patents
用于治疗非小细胞肺癌的氨基吡啶衍生物 Download PDFInfo
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- CN114173785A CN114173785A CN202080050485.9A CN202080050485A CN114173785A CN 114173785 A CN114173785 A CN 114173785A CN 202080050485 A CN202080050485 A CN 202080050485A CN 114173785 A CN114173785 A CN 114173785A
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- lung cancer
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- A—HUMAN NECESSITIES
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Abstract
一种取代的2‑氨基吡啶衍生物在治疗非小细胞肺癌中的用途，特别是在治疗患者先前接受过至少一种化疗药物和/或靶向药物的非小细胞肺癌中的用途；所述取代的2‑氨基吡啶衍生物为化合物I(化学名称为5‑((R)‑1‑(2,6‑二氯‑3‑氟苯基)乙氧基)‑4'‑甲氧基‑6'‑((S)‑2‑甲基哌嗪‑1‑基)‑3,3'‑联吡啶‑6‑胺)或其药学上可接受的盐。
Description
PCT国内申请，说明书已公开。
Claims (20)
- PCT国内申请，权利要求书已公开。
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910707409X | 2019-08-01 | ||
| CN201910707409 | 2019-08-01 | ||
| PCT/CN2020/106629 WO2021018310A1 (zh) | 2019-08-01 | 2020-08-03 | 用于治疗非小细胞肺癌的氨基吡啶衍生物 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN114173785A true CN114173785A (zh) | 2022-03-11 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202080050485.9A Pending CN114173785A (zh) | 2019-08-01 | 2020-08-03 | 用于治疗非小细胞肺癌的氨基吡啶衍生物 |
Country Status (2)
| Country | Link |
|---|---|
| CN (1) | CN114173785A (zh) |
| WO (1) | WO2021018310A1 (zh) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115484955A (zh) * | 2020-04-30 | 2022-12-16 | 正大天晴药业集团股份有限公司 | 用于治疗met基因异常疾病的氨基吡啶衍生物 |
| WO2024017334A1 (zh) * | 2022-07-22 | 2024-01-25 | 贝达药业股份有限公司 | 用于rdaa阳性疾病的诊断和治疗的方法和试剂盒 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106536510A (zh) * | 2014-07-31 | 2017-03-22 | 正大天晴药业集团股份有限公司 | 吡啶取代的2‑氨基吡啶类蛋白激酶抑制剂 |
| CN106999484A (zh) * | 2014-12-09 | 2017-08-01 | 正大天晴药业集团股份有限公司 | 治疗非小细胞肺癌的喹啉衍生物 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2716617T3 (es) * | 2013-02-02 | 2019-06-13 | Chia Tai Tianqing Pharmaceutical Group Co Ltd | Inhibidor de proteína quinasa de 2-aminopiridina sustituida |
| CN110330483A (zh) * | 2015-07-30 | 2019-10-15 | 正大天晴药业集团股份有限公司 | 吡啶取代的2-氨基吡啶类蛋白激酶抑制剂的结晶 |
| CN108264500B (zh) * | 2016-12-31 | 2020-04-21 | 正大天晴药业集团股份有限公司 | 取代的2-氨基吡啶类化合物及制备方法 |
| CN108264501B (zh) * | 2016-12-31 | 2020-04-21 | 正大天晴药业集团股份有限公司 | 取代的2-氨基吡啶类化合物及其制备方法 |
-
2020
- 2020-08-03 CN CN202080050485.9A patent/CN114173785A/zh active Pending
- 2020-08-03 WO PCT/CN2020/106629 patent/WO2021018310A1/zh active Application Filing
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106536510A (zh) * | 2014-07-31 | 2017-03-22 | 正大天晴药业集团股份有限公司 | 吡啶取代的2‑氨基吡啶类蛋白激酶抑制剂 |
| CN106999484A (zh) * | 2014-12-09 | 2017-08-01 | 正大天晴药业集团股份有限公司 | 治疗非小细胞肺癌的喹啉衍生物 |
Non-Patent Citations (1)
| Title |
|---|
| 张昱等: ""靶向ＲOS1 酪氨酸激酶小分子抑制剂的研究进展"", 《沈阳药科大学学报》, vol. 34, no. 3, pages 266 - 274 * |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2021018310A1 (zh) | 2021-02-04 |
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