DK3328395T3 - Ny brug af dextransulfat - Google Patents

Ny brug af dextransulfat Download PDF

Info

Publication number
DK3328395T3
DK3328395T3 DK16830923.5T DK16830923T DK3328395T3 DK 3328395 T3 DK3328395 T3 DK 3328395T3 DK 16830923 T DK16830923 T DK 16830923T DK 3328395 T3 DK3328395 T3 DK 3328395T3
Authority
DK
Denmark
Prior art keywords
dextransulphate
new use
new
Prior art date
Application number
DK16830923.5T
Other languages
Danish (da)
English (en)
Inventor
Lars Bruce
Adam Bruce
Anders Waas
Original Assignee
Tx Medic Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tx Medic Ab filed Critical Tx Medic Ab
Application granted granted Critical
Publication of DK3328395T3 publication Critical patent/DK3328395T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/721—Dextrans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/02—Dextran; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Polymers & Plastics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
DK16830923.5T 2015-07-30 2016-07-15 Ny brug af dextransulfat DK3328395T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE1551050A SE539575C2 (en) 2015-07-30 2015-07-30 Dextran sulfate for use in treating, inhibiting or preventing cardiac fibrosis
PCT/SE2016/050720 WO2017018922A1 (en) 2015-07-30 2016-07-15 New use of dextran sulfate

Publications (1)

Publication Number Publication Date
DK3328395T3 true DK3328395T3 (da) 2021-08-09

Family

ID=57884849

Family Applications (1)

Application Number Title Priority Date Filing Date
DK16830923.5T DK3328395T3 (da) 2015-07-30 2016-07-15 Ny brug af dextransulfat

Country Status (11)

Country Link
US (1) US10478451B2 (enExample)
EP (1) EP3328395B1 (enExample)
JP (1) JP6837679B2 (enExample)
CN (2) CN114712385A (enExample)
BR (1) BR112018001942A2 (enExample)
DK (1) DK3328395T3 (enExample)
EA (1) EA034313B1 (enExample)
ES (1) ES2882115T3 (enExample)
HK (1) HK1246640A1 (enExample)
SE (1) SE539575C2 (enExample)
WO (1) WO2017018922A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2777836T3 (es) * 2017-05-17 2020-08-06 Tx Medic Ab Tratamiento del glaucoma
WO2018212708A1 (en) * 2017-05-17 2018-11-22 Tx Medic Ab Treatment of glaucoma
IL272935B2 (en) * 2017-09-08 2025-04-01 Tx Medic Ab New use of dextran sulfate
CA3093027A1 (en) * 2018-03-09 2019-09-12 Carmeda Ab Improvements to processes for immobilising biological entities
SE543275C2 (en) * 2019-03-07 2020-11-10 Tx Medic Ab Treatment efficiency evaluation
SE544447C2 (en) * 2020-09-29 2022-05-31 Tx Medic Ab Treatment of fatty liver diseases

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5605938A (en) * 1991-05-31 1997-02-25 Gliatech, Inc. Methods and compositions for inhibition of cell invasion and fibrosis using dextran sulfate
EP0868191A1 (en) 1995-12-18 1998-10-07 Stichting Sanquin Bloedvoorziening Potentiation of complement and coagulation inhibitory properties of c1-inhibitor.
US20040224922A1 (en) 1999-08-26 2004-11-11 Malcolm King Use of charged dextran as a mucoactive agent and methods and pharmaceutical compositions relating thereto
SE525461C3 (sv) * 2002-11-28 2005-03-23 Prophymed Ab Ny användning av dextransulfat
WO2007028053A2 (en) * 2005-09-02 2007-03-08 X-Cell Medical Incorporated Methods of treating and preventing cardiac disorders
WO2007075388A2 (en) * 2005-12-15 2007-07-05 X-Cell Medical Incorporated Methods of locally treating and preventing cardiac disorders
CA2685208C (en) * 2007-04-24 2014-04-08 Novelmed Therapeutics, Inc. Methods and compositions of inhibiting complement and cellular activation with dextran sulfate
WO2011091167A2 (en) * 2010-01-22 2011-07-28 The General Hospital Corporation Lysophosphatidic acid receptor targeting for scleroderma and other fibrotic diseases
US9393289B2 (en) * 2011-10-18 2016-07-19 Csl Behring Gmbh Use of sulfated glycosaminoglycans for improving the bioavailability of factor VIII
CN102973593A (zh) * 2012-11-26 2013-03-20 合肥博太医药生物技术发展有限公司 硫酸葡聚糖在制备治疗肝纤维化药物中的应用
WO2015190989A1 (en) * 2014-06-12 2015-12-17 Tx Medic Ab The use of dextran sulfate having an average molecular weight below 10000 da for inducing angiogenisis in a subject
PT3154551T (pt) * 2014-06-12 2019-01-18 Tx Medic Ab A utilização de sulfato de dextrano tendo uma massa molecular média inferior a 10000 da para induzir angiogénese num sujeito

Also Published As

Publication number Publication date
JP6837679B2 (ja) 2021-03-03
JP2018521086A (ja) 2018-08-02
ES2882115T3 (es) 2021-12-01
EP3328395A4 (en) 2018-06-20
BR112018001942A2 (pt) 2018-09-18
US10478451B2 (en) 2019-11-19
CN107921055A (zh) 2018-04-17
US20180221403A1 (en) 2018-08-09
HK1246640A1 (zh) 2018-09-14
EP3328395A1 (en) 2018-06-06
CN114712385A (zh) 2022-07-08
SE1551050A1 (en) 2017-01-31
EA201890212A1 (ru) 2018-06-29
EP3328395B1 (en) 2021-06-09
EA034313B1 (ru) 2020-01-28
WO2017018922A1 (en) 2017-02-02
SE539575C2 (en) 2017-10-17

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