DK3325501T3 - Anti-tumor immunresponser til modificerede selv-epitoper - Google Patents
Anti-tumor immunresponser til modificerede selv-epitoper Download PDFInfo
- Publication number
- DK3325501T3 DK3325501T3 DK16744839.8T DK16744839T DK3325501T3 DK 3325501 T3 DK3325501 T3 DK 3325501T3 DK 16744839 T DK16744839 T DK 16744839T DK 3325501 T3 DK3325501 T3 DK 3325501T3
- Authority
- DK
- Denmark
- Prior art keywords
- epitopes
- immune responses
- tumor immune
- modified self
- self
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
- A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
- A61K47/6811—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y402/00—Carbon-oxygen lyases (4.2)
- C12Y402/01—Hydro-lyases (4.2.1)
- C12Y402/01011—Phosphopyruvate hydratase (4.2.1.11), i.e. enolase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Mycology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Enzymes And Modification Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1512703.8A GB201512703D0 (en) | 2015-07-20 | 2015-07-20 | Anti-tumour immune responses to modified self-epitopes |
| PCT/GB2016/052181 WO2017013425A1 (en) | 2015-07-20 | 2016-07-19 | Anti-tumour immune responses to modified self-epitopes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3325501T3 true DK3325501T3 (da) | 2020-12-07 |
Family
ID=54013290
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK16744839.8T DK3325501T3 (da) | 2015-07-20 | 2016-07-19 | Anti-tumor immunresponser til modificerede selv-epitoper |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US10695438B2 (da) |
| EP (1) | EP3325501B1 (da) |
| JP (2) | JP7034900B2 (da) |
| KR (1) | KR20180030552A (da) |
| CN (1) | CN108350031A (da) |
| AU (1) | AU2016295337B2 (da) |
| BR (1) | BR112017025036A2 (da) |
| CA (1) | CA2985022A1 (da) |
| DK (1) | DK3325501T3 (da) |
| ES (1) | ES2827020T3 (da) |
| GB (1) | GB201512703D0 (da) |
| HK (1) | HK1248253A1 (da) |
| PT (1) | PT3325501T (da) |
| WO (1) | WO2017013425A1 (da) |
| ZA (1) | ZA201708008B (da) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112142824B (zh) * | 2019-06-27 | 2022-03-11 | 深圳市东贵博康生化科技有限公司 | 具有诱导细胞毒性t淋巴细胞能力的多肽及其应用 |
| CN111398308B (zh) * | 2020-03-27 | 2023-01-17 | 上海健康医学院 | 一种片剂、胶囊铝塑泡罩包装质量自动检测方法及系统 |
| IT202100024779A1 (it) * | 2021-09-28 | 2023-03-28 | Univ Degli Studi Di Torino | Vaccino a DNA per l’uso nel trattamento profilattico o terapeutico dell’adenocarcinoma duttale pancreatico |
| CN114478784B (zh) * | 2022-01-07 | 2022-11-25 | 陕西脉元生物科技有限公司 | 一种eno2单克隆抗体1c5及其制备方法和应用 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004020462A1 (ja) | 2002-08-27 | 2004-03-11 | Fujii, Nobutaka | Ｃｘｃｒ４拮抗薬およびその用途 |
| US7670604B2 (en) | 2002-12-13 | 2010-03-02 | Aurelium Biopharma, Inc. | Vimentin directed diagnostics and therapeutics for multidrug resistant neoplastic disease |
| DE102005029845B4 (de) | 2005-06-27 | 2017-03-23 | Orgentec Diagnostika Gmbh | Verfahren zur Diagnose von rheumatischen Erkrankungen |
| US20070248628A1 (en) | 2005-12-06 | 2007-10-25 | Keller Lorraine H | Immunogens in cancer stem cells |
| US8404810B2 (en) | 2006-02-17 | 2013-03-26 | Five Prime Therapeutics, Inc. | Compositions and methods of use for modulators of polypeptides and polynucleotides in treating breast cancer and melanoma |
| EP2015785A4 (en) | 2006-04-24 | 2009-07-15 | Shantha West Inc | ANTIGEN AGRM2 |
| EP2567707B1 (en) | 2007-07-27 | 2016-10-05 | Immatics Biotechnologies GmbH | Composition of tumour-associated peptides and related anti-cancer vaccine |
| IL225538A0 (en) | 2009-03-30 | 2013-06-27 | Nestec Sa | Methods for the identification of anti-immune reaction peptides of anti-citrullinates |
| WO2012095849A1 (en) | 2011-01-10 | 2012-07-19 | Biokine Therapeutics Ltd. | Peptides and compositions for the treatment of neuroectodermal derived tumors and retinoblastoma |
| US20130309229A1 (en) | 2011-01-28 | 2013-11-21 | The United States Government As Represented By The Department Of Veterans Affairs | Recombinant t cell ligands and antibodies that bind b cells for the treatment of autoimmune diseases |
| EP3412680B1 (en) * | 2011-04-05 | 2020-11-04 | Curara AB | Novel peptides that bind to types of mhc class ii and their use in diagnosis and treatment |
| US20120295292A1 (en) | 2011-05-19 | 2012-11-22 | University Of South Carolina | Detecting Protein Arginine Deiminase (PAD) Activity in Human Tissues and Sera |
| US20130274125A1 (en) | 2012-04-16 | 2013-10-17 | Bio-Rad Laboratories Inc. | Multiplex immunoassay for rheumatoid arthritis and other autoimmune diseases |
| GB201214007D0 (en) * | 2012-08-07 | 2012-09-19 | Scancell Ltd | Anti-tumour immune responses to modified self-epitopes |
-
2015
- 2015-07-20 GB GBGB1512703.8A patent/GB201512703D0/en not_active Ceased
-
2016
- 2016-07-19 WO PCT/GB2016/052181 patent/WO2017013425A1/en active Application Filing
- 2016-07-19 ES ES16744839T patent/ES2827020T3/es active Active
- 2016-07-19 KR KR1020187002628A patent/KR20180030552A/ko not_active Application Discontinuation
- 2016-07-19 PT PT167448398T patent/PT3325501T/pt unknown
- 2016-07-19 BR BR112017025036A patent/BR112017025036A2/pt active Search and Examination
- 2016-07-19 JP JP2018502787A patent/JP7034900B2/ja active Active
- 2016-07-19 DK DK16744839.8T patent/DK3325501T3/da active
- 2016-07-19 EP EP16744839.8A patent/EP3325501B1/en active Active
- 2016-07-19 CA CA2985022A patent/CA2985022A1/en active Pending
- 2016-07-19 US US15/746,077 patent/US10695438B2/en active Active
- 2016-07-19 AU AU2016295337A patent/AU2016295337B2/en active Active
- 2016-07-19 CN CN201680043139.1A patent/CN108350031A/zh active Pending
-
2017
- 2017-11-24 ZA ZA2017/08008A patent/ZA201708008B/en unknown
-
2018
- 2018-06-14 HK HK18107761.2A patent/HK1248253A1/zh unknown
-
2020
- 2020-03-19 US US16/823,814 patent/US11382985B2/en active Active
-
2021
- 2021-12-24 JP JP2021210507A patent/JP2022058412A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP3325501A1 (en) | 2018-05-30 |
| JP2022058412A (ja) | 2022-04-12 |
| ES2827020T3 (es) | 2021-05-19 |
| AU2016295337B2 (en) | 2020-07-09 |
| EP3325501B1 (en) | 2020-09-09 |
| AU2016295337A1 (en) | 2017-12-21 |
| HK1248253A1 (zh) | 2018-10-12 |
| CN108350031A (zh) | 2018-07-31 |
| US10695438B2 (en) | 2020-06-30 |
| JP2018523475A (ja) | 2018-08-23 |
| ZA201708008B (en) | 2019-09-25 |
| WO2017013425A1 (en) | 2017-01-26 |
| KR20180030552A (ko) | 2018-03-23 |
| PT3325501T (pt) | 2020-11-03 |
| CA2985022A1 (en) | 2017-01-26 |
| US20180207291A1 (en) | 2018-07-26 |
| JP7034900B2 (ja) | 2022-03-14 |
| US20200330605A1 (en) | 2020-10-22 |
| US11382985B2 (en) | 2022-07-12 |
| BR112017025036A2 (pt) | 2018-08-07 |
| GB201512703D0 (en) | 2015-08-26 |
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