DK3571208T3 - Immunproteasominhibitorer - Google Patents

Immunproteasominhibitorer Download PDF

Info

Publication number
DK3571208T3
DK3571208T3 DK18716009.8T DK18716009T DK3571208T3 DK 3571208 T3 DK3571208 T3 DK 3571208T3 DK 18716009 T DK18716009 T DK 18716009T DK 3571208 T3 DK3571208 T3 DK 3571208T3
Authority
DK
Denmark
Prior art keywords
proteasominhibitors
immune
immune proteasominhibitors
Prior art date
Application number
DK18716009.8T
Other languages
English (en)
Inventor
Yan Lou
Timothy Duncan Owens
Kenneth Albert Brameld
David Michael Goldstein
Original Assignee
Principia Biopharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Principia Biopharma Inc filed Critical Principia Biopharma Inc
Application granted granted Critical
Publication of DK3571208T3 publication Critical patent/DK3571208T3/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00Compounds containing elements of Groups 3 or 13 of the Periodic System
    • C07F5/02Boron compounds
    • C07F5/025Boronic and borinic acid compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/69Boron compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
DK18716009.8T 2017-01-18 2018-01-16 Immunproteasominhibitorer DK3571208T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762447717P 2017-01-18 2017-01-18
US201762508771P 2017-05-19 2017-05-19
PCT/US2018/013823 WO2018136401A1 (en) 2017-01-18 2018-01-16 Immunoproteasome inhibitors

Publications (1)

Publication Number Publication Date
DK3571208T3 true DK3571208T3 (da) 2021-05-10

Family

ID=61906812

Family Applications (1)

Application Number Title Priority Date Filing Date
DK18716009.8T DK3571208T3 (da) 2017-01-18 2018-01-16 Immunproteasominhibitorer

Country Status (20)

Country Link
US (1) US11154563B2 (da)
EP (1) EP3571208B1 (da)
JP (1) JP7071400B6 (da)
KR (1) KR102534947B1 (da)
CN (1) CN110248949B (da)
AU (1) AU2018210839B2 (da)
CA (1) CA3049887A1 (da)
DK (1) DK3571208T3 (da)
ES (1) ES2874638T3 (da)
HR (1) HRP20210663T1 (da)
HU (1) HUE054460T2 (da)
LT (1) LT3571208T (da)
MX (1) MX2019008436A (da)
PL (1) PL3571208T3 (da)
PT (1) PT3571208T (da)
RS (1) RS61811B1 (da)
SI (1) SI3571208T1 (da)
TW (1) TWI821169B (da)
UY (1) UY37569A (da)
WO (1) WO2018136401A1 (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11202003867SA (en) * 2017-11-16 2020-05-28 Principia Biopharma Inc Immunoproteasome inhibitors
DK3710457T3 (da) * 2017-11-16 2022-10-24 Principia Biopharma Inc Immunproteasomhæmmere
CN113135943A (zh) * 2020-01-19 2021-07-20 首药控股(北京)有限公司 硼酸衍生物
WO2024006337A1 (en) * 2022-06-30 2024-01-04 Principia Biopharma Inc. Cyclic boronic esters and their uses

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4107288A (en) 1974-09-18 1978-08-15 Pharmaceutical Society Of Victoria Injectable compositions, nanoparticles useful therein, and process of manufacturing same
US4963655A (en) 1988-05-27 1990-10-16 Mayo Foundation For Medical Education And Research Boron analogs of amino acid/peptide protease inhibitors
US5145684A (en) 1991-01-25 1992-09-08 Sterling Drug Inc. Surface modified drug nanoparticles
IL111175A0 (en) 1993-10-07 1994-12-29 Du Pont Merck Pharma Electrophilic peptide analogs as inhibitors of trypsin-like serine proteases and pharmaceutical compositions containing them
UA88771C2 (ru) * 2003-08-14 2009-11-25 Сефалон, Инк. Ингибиторы протеасомы и способ их применения (варианты)
US7576206B2 (en) 2003-08-14 2009-08-18 Cephalon, Inc. Proteasome inhibitors and methods of using the same
BRPI0507972A (pt) * 2004-02-23 2007-07-24 Tufts College composto ,composição farmacêutica , uso de um composto, método para inibição da atividade proteolìtica de uma enzima de clivagem pós prolina e composição farmacêutica embalada
US10654843B2 (en) 2014-06-20 2020-05-19 Principia Biopharma Inc. LMP7 inhibitors
MX2017004043A (es) * 2014-10-01 2017-07-04 Merck Patent Gmbh Derivados de acido boronico.
MX2017003999A (es) * 2014-10-01 2018-02-09 Merck Patent Gmbh Derivados de acido boronico.
SG11202003867SA (en) 2017-11-16 2020-05-28 Principia Biopharma Inc Immunoproteasome inhibitors
DK3710457T3 (da) 2017-11-16 2022-10-24 Principia Biopharma Inc Immunproteasomhæmmere

Also Published As

Publication number Publication date
MX2019008436A (es) 2019-09-18
SI3571208T1 (sl) 2021-06-30
RS61811B1 (sr) 2021-06-30
JP7071400B2 (ja) 2022-05-18
KR102534947B1 (ko) 2023-05-23
LT3571208T (lt) 2021-05-25
US11154563B2 (en) 2021-10-26
WO2018136401A1 (en) 2018-07-26
CN110248949A (zh) 2019-09-17
JP7071400B6 (ja) 2022-06-07
PL3571208T3 (pl) 2021-09-20
ES2874638T3 (es) 2021-11-05
US20190336515A1 (en) 2019-11-07
HRP20210663T1 (hr) 2021-05-28
EP3571208B1 (en) 2021-03-10
EP3571208A1 (en) 2019-11-27
AU2018210839B2 (en) 2022-01-20
AU2018210839A1 (en) 2019-07-25
HUE054460T2 (hu) 2021-09-28
JP2020506956A (ja) 2020-03-05
CN110248949B (zh) 2023-02-17
TW201831446A (zh) 2018-09-01
TWI821169B (zh) 2023-11-11
PT3571208T (pt) 2021-04-13
KR20190104600A (ko) 2019-09-10
UY37569A (es) 2018-08-31
CA3049887A1 (en) 2018-07-26

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