DK3321377T3 - Fremgangsmåde til bestemmelse af sensitivitet over for en samtidig inhibitor mod parp og tankyrase - Google Patents
Fremgangsmåde til bestemmelse af sensitivitet over for en samtidig inhibitor mod parp og tankyrase Download PDFInfo
- Publication number
- DK3321377T3 DK3321377T3 DK16821647.1T DK16821647T DK3321377T3 DK 3321377 T3 DK3321377 T3 DK 3321377T3 DK 16821647 T DK16821647 T DK 16821647T DK 3321377 T3 DK3321377 T3 DK 3321377T3
- Authority
- DK
- Denmark
- Prior art keywords
- tankyrace
- parp
- contemporary
- inhibitor
- procedure
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4746—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used p53
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1077—Pentosyltransferases (2.4.2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/93—Ligases (6)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y204/00—Glycosyltransferases (2.4)
- C12Y204/02—Pentosyltransferases (2.4.2)
- C12Y204/0203—NAD+ ADP-ribosyltransferase (2.4.2.30), i.e. tankyrase or poly(ADP-ribose) polymerase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y605/00—Ligases forming phosphoric ester bonds (6.5)
- C12Y605/01—Ligases forming phosphoric ester bonds (6.5) forming phosphoric ester bonds (6.5.1)
- C12Y605/01001—DNA ligase (ATP) (6.5.1.1)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Biomedical Technology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Chemical Kinetics & Catalysis (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020150095924A KR101775356B1 (ko) | 2015-07-06 | 2015-07-06 | Parp 및 탄키라제 동시 저해제에 대한 감수성 결정 방법 |
| PCT/KR2016/007333 WO2017007241A1 (ko) | 2015-07-06 | 2016-07-06 | Parp 및 탄키라제 동시 저해제에 대한 감수성 결정 방법 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3321377T3 true DK3321377T3 (da) | 2022-02-14 |
Family
ID=57685290
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK16821647.1T DK3321377T3 (da) | 2015-07-06 | 2016-07-06 | Fremgangsmåde til bestemmelse af sensitivitet over for en samtidig inhibitor mod parp og tankyrase |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US10683553B2 (da) |
| EP (1) | EP3321377B1 (da) |
| KR (1) | KR101775356B1 (da) |
| CN (1) | CN107922976A (da) |
| DK (1) | DK3321377T3 (da) |
| ES (1) | ES2906454T3 (da) |
| PL (1) | PL3321377T3 (da) |
| WO (1) | WO2017007241A1 (da) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016200101A2 (ko) * | 2015-06-09 | 2016-12-15 | 제일약품주식회사 | 트리사이클릭 유도체 화합물, 이의 제조방법 및 이를 포함하는 약학적 조성물 |
| CA3219248A1 (en) * | 2021-05-18 | 2022-11-24 | Hyun Ju Cha | Parp inhibitor-resistant cancer therapeutic agent |
| CA3219303A1 (en) * | 2021-05-18 | 2022-11-24 | Onconic Therapeutics Inc. | Crystalline form of tricyclic derivative compound, method for preparing same, and pharmaceutical composition comprising same |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2559652C (en) * | 2004-03-15 | 2017-02-14 | Sunesis Pharmaceuticals, Inc. | Methods of using sns-595 in treating cancer |
| CA2639416C (en) * | 2007-09-11 | 2019-12-31 | F. Hoffmann-La Roche Ag | Diagnostic test for susceptibility to b-raf kinase inhibitors |
| BRPI0915273B1 (pt) | 2008-11-11 | 2021-08-03 | Je Il Pharmaceutical Co., Ltd | Derivado tricíclico ou seus sais farmaceuticamente aceitáveis e seus métodos de preparação |
| RS55062B1 (sr) | 2012-05-04 | 2016-12-30 | Merck Patent Gmbh | Pirolotriazinon derivati |
| WO2016200101A2 (ko) | 2015-06-09 | 2016-12-15 | 제일약품주식회사 | 트리사이클릭 유도체 화합물, 이의 제조방법 및 이를 포함하는 약학적 조성물 |
-
2015
- 2015-07-06 KR KR1020150095924A patent/KR101775356B1/ko active IP Right Grant
-
2016
- 2016-07-06 DK DK16821647.1T patent/DK3321377T3/da active
- 2016-07-06 US US15/742,408 patent/US10683553B2/en active Active
- 2016-07-06 CN CN201680040111.2A patent/CN107922976A/zh active Pending
- 2016-07-06 PL PL16821647T patent/PL3321377T3/pl unknown
- 2016-07-06 EP EP16821647.1A patent/EP3321377B1/en active Active
- 2016-07-06 WO PCT/KR2016/007333 patent/WO2017007241A1/ko active Application Filing
- 2016-07-06 ES ES16821647T patent/ES2906454T3/es active Active
-
2020
- 2020-05-12 US US15/930,199 patent/US20200354794A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| KR101775356B1 (ko) | 2017-09-06 |
| US20180327851A1 (en) | 2018-11-15 |
| US10683553B2 (en) | 2020-06-16 |
| ES2906454T3 (es) | 2022-04-18 |
| CN107922976A (zh) | 2018-04-17 |
| PL3321377T3 (pl) | 2022-03-28 |
| EP3321377A1 (en) | 2018-05-16 |
| WO2017007241A1 (ko) | 2017-01-12 |
| EP3321377A4 (en) | 2018-12-05 |
| US20200354794A1 (en) | 2020-11-12 |
| EP3321377B1 (en) | 2021-12-29 |
| KR20170005627A (ko) | 2017-01-16 |
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