RS55062B1 - Pirolotriazinon derivati - Google Patents

Pirolotriazinon derivati

Info

Publication number
RS55062B1
RS55062B1 RS20160696A RSP20160696A RS55062B1 RS 55062 B1 RS55062 B1 RS 55062B1 RS 20160696 A RS20160696 A RS 20160696A RS P20160696 A RSP20160696 A RS P20160696A RS 55062 B1 RS55062 B1 RS 55062B1
Authority
RS
Serbia
Prior art keywords
pyrrolotriazinone derivatives
pyrrolotriazinone
derivatives
Prior art date
Application number
RS20160696A
Other languages
English (en)
Inventor
Dieter Dorsch
Hans-Peter Buchstaller
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of RS55062B1 publication Critical patent/RS55062B1/sr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
RS20160696A 2012-05-04 2013-04-06 Pirolotriazinon derivati RS55062B1 (sr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12003445 2012-05-04
PCT/EP2013/001026 WO2013164061A1 (en) 2012-05-04 2013-04-06 Pyrrolotriazinone derivatives
EP13714859.9A EP2844659B1 (en) 2012-05-04 2013-04-06 Pyrrolotriazinone derivatives

Publications (1)

Publication Number Publication Date
RS55062B1 true RS55062B1 (sr) 2016-12-30

Family

ID=48050660

Family Applications (1)

Application Number Title Priority Date Filing Date
RS20160696A RS55062B1 (sr) 2012-05-04 2013-04-06 Pirolotriazinon derivati

Country Status (22)

Country Link
US (1) US9174995B2 (sr)
EP (1) EP2844659B1 (sr)
JP (1) JP6097820B2 (sr)
KR (1) KR20150006873A (sr)
CN (1) CN104271580B (sr)
AR (1) AR090896A1 (sr)
AU (1) AU2013257018B2 (sr)
CA (1) CA2872334C (sr)
EA (1) EA027628B1 (sr)
ES (1) ES2587939T3 (sr)
HK (1) HK1205740A1 (sr)
HR (1) HRP20161033T1 (sr)
HU (1) HUE028325T2 (sr)
IL (1) IL235414A (sr)
MX (1) MX357502B (sr)
PL (1) PL2844659T3 (sr)
PT (1) PT2844659T (sr)
RS (1) RS55062B1 (sr)
SG (1) SG11201406997WA (sr)
SI (1) SI2844659T1 (sr)
WO (1) WO2013164061A1 (sr)
ZA (1) ZA201408876B (sr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104302358B (zh) 2012-03-07 2017-12-05 癌症研究协会:皇家癌症医院 3‑芳基‑5‑取代的异喹啉‑1‑酮化合物和它们的治疗用途
WO2015036759A1 (en) 2013-09-11 2015-03-19 Institute Of Cancer Research: Royal Cancer Hospital (The) 3-aryl-5-substituted-isoquinolin-1-one compounds and their therapeutic use
NO3087076T3 (sr) * 2013-12-23 2018-02-24
UY36060A (es) 2014-04-02 2015-10-30 Bayer Pharma AG Compuestos de azol sustituidos con amida
PT3130592T (pt) * 2014-04-10 2019-11-21 Hubei Bio Pharmaceutical Industrial Tech Institute Inc Análogos do composto 4h-pirazolo[1,5-]benzimidazole como inibidores de parp
KR20160007347A (ko) * 2014-07-11 2016-01-20 에스티팜 주식회사 신규한 이미다조트리아지논 또는 이미다조피라지논 유도체, 및 이들의 용도
KR101775356B1 (ko) * 2015-07-06 2017-09-06 재단법인 아산사회복지재단 Parp 및 탄키라제 동시 저해제에 대한 감수성 결정 방법
WO2017059191A1 (en) 2015-09-30 2017-04-06 Quartet Medicine, Inc. Heteroaryl derivatives as sepiapterin reductase inhibitors
WO2017055313A1 (en) 2015-10-01 2017-04-06 Bayer Pharma Aktiengesellschaft Amido-substituted azole compounds
WO2017055316A1 (en) 2015-10-01 2017-04-06 Bayer Pharma Aktiengesellschaft Amido-substituted azole compounds
US10570137B2 (en) 2015-11-16 2020-02-25 Topadur Pharma Ag 2-phenyl-3,4-dihydropyrrolo[2,1 -F] [1,2,4]triazinone derivatives as phosphodiesterase inhibitors and uses thereof
WO2017156350A1 (en) 2016-03-09 2017-09-14 K-Gen, Inc. Methods of cancer treatment
WO2018078009A1 (en) 2016-10-29 2018-05-03 Bayer Pharma Aktiengesellschaft Amido-substituted cyclohexane derivatives
WO2018078005A1 (en) 2016-10-29 2018-05-03 Bayer Pharma Aktiengesellschaft Amido-substituted azaspiro derivatives as tankyrase inhibitors
WO2018087126A1 (en) 2016-11-09 2018-05-17 Bayer Pharma Aktiengesellschaft Amido-substituted cyclohexane derivatives as inhibitors of tankyrase
CN109180702B (zh) * 2018-10-29 2021-11-30 四川大学 一种噻吩并嘧啶酮化合物及其用途
CN111961058B (zh) * 2020-08-03 2022-12-16 天津全和诚科技有限责任公司 4-氨基-吡咯并三嗪衍生物及其制备方法和用途

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9624482D0 (en) 1995-12-18 1997-01-15 Zeneca Phaema S A Chemical compounds
KR19990082463A (ko) 1996-02-13 1999-11-25 돈 리사 로얄 혈관 내피 성장 인자 억제제로서의 퀴나졸린유도체
CN1116286C (zh) 1996-03-05 2003-07-30 曾尼卡有限公司 4-苯胺基喹唑啉衍生物
GB9718972D0 (en) 1996-09-25 1997-11-12 Zeneca Ltd Chemical compounds
GB9714249D0 (en) 1997-07-08 1997-09-10 Angiogene Pharm Ltd Vascular damaging agents
GB9900334D0 (en) 1999-01-07 1999-02-24 Angiogene Pharm Ltd Tricylic vascular damaging agents
GB9900752D0 (en) 1999-01-15 1999-03-03 Angiogene Pharm Ltd Benzimidazole vascular damaging agents
IL152682A0 (en) 2000-05-31 2003-06-24 Astrazeneca Ab Indole derivatives with vascular damaging activity
PL359181A1 (en) 2000-07-07 2004-08-23 Angiogene Pharmaceuticals Limited Colchinol derivatives as angiogenesis inhibitors
CN1255391C (zh) 2000-07-07 2006-05-10 安吉奥金尼药品有限公司 作为血管破坏剂的colchinol衍生物
US7223766B2 (en) * 2003-03-28 2007-05-29 Scios, Inc. Bi-cyclic pyrimidine inhibitors of TGFβ
WO2006035061A1 (en) * 2004-09-30 2006-04-06 Tibotec Pharmaceuticals Ltd. Hcv inhibiting bi-cyclic pyrimidines
WO2008092861A1 (en) * 2007-01-30 2008-08-07 Janssen Pharmaceutica N.V. Bicyclic derivatives as ep4 agonists
WO2008107478A1 (en) * 2007-03-08 2008-09-12 Janssen Pharmaceutica Nv Quinolinone derivatives as parp and tank inhibitors
CN101687874B (zh) * 2007-04-18 2013-01-30 百时美施贵宝公司 吡咯并三嗪激酶抑制剂

Also Published As

Publication number Publication date
EP2844659A1 (en) 2015-03-11
HK1205740A1 (en) 2015-12-24
PT2844659T (pt) 2016-08-31
KR20150006873A (ko) 2015-01-19
PL2844659T3 (pl) 2016-11-30
ES2587939T3 (es) 2016-10-27
US20150133453A1 (en) 2015-05-14
EA201401212A1 (ru) 2015-08-31
US9174995B2 (en) 2015-11-03
JP2015515961A (ja) 2015-06-04
SG11201406997WA (en) 2014-11-27
AU2013257018B2 (en) 2017-02-16
AR090896A1 (es) 2014-12-17
CN104271580A (zh) 2015-01-07
HRP20161033T1 (hr) 2016-10-21
AU2013257018A1 (en) 2014-12-18
CA2872334A1 (en) 2013-11-07
ZA201408876B (en) 2017-06-28
JP6097820B2 (ja) 2017-03-15
MX357502B (es) 2018-07-12
WO2013164061A8 (en) 2014-11-06
EP2844659B1 (en) 2016-05-25
CN104271580B (zh) 2017-02-22
WO2013164061A1 (en) 2013-11-07
EA027628B1 (ru) 2017-08-31
CA2872334C (en) 2020-06-30
MX2014013090A (es) 2014-12-08
SI2844659T1 (sl) 2016-10-28
HUE028325T2 (en) 2016-12-28
IL235414A (en) 2017-11-30

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