DK3318574T3 - Polypeptid med beta-glucosidase-aktivitet og anvendelser deraf - Google Patents

Polypeptid med beta-glucosidase-aktivitet og anvendelser deraf Download PDF

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Publication number
DK3318574T3
DK3318574T3 DK17200641.3T DK17200641T DK3318574T3 DK 3318574 T3 DK3318574 T3 DK 3318574T3 DK 17200641 T DK17200641 T DK 17200641T DK 3318574 T3 DK3318574 T3 DK 3318574T3
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Denmark
Prior art keywords
polypeptid
glucosidase activity
beta glucosidase
beta
activity
Prior art date
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DK17200641.3T
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English (en)
Inventor
Margot Elisabeth Francoise Schooneveld-Bergmans
Wilbert Herman Marie Heijne
Jong René Marcel De
Robbertus Antonius Damveld
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Dsm Ip Assets Bv
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Application filed by Dsm Ip Assets Bv filed Critical Dsm Ip Assets Bv
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Publication of DK3318574T3 publication Critical patent/DK3318574T3/da

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2434—Glucanases acting on beta-1,4-glucosidic bonds
    • C12N9/2445—Beta-glucosidase (3.2.1.21)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2434—Glucanases acting on beta-1,4-glucosidic bonds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2434—Glucanases acting on beta-1,4-glucosidic bonds
    • C12N9/2437—Cellulases (3.2.1.4; 3.2.1.74; 3.2.1.91; 3.2.1.150)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/02—Monosaccharides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/14—Preparation of compounds containing saccharide radicals produced by the action of a carbohydrase (EC 3.2.x), e.g. by alpha-amylase, e.g. by cellulase, hemicellulase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01021—Beta-glucosidase (3.2.1.21)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P2203/00—Fermentation products obtained from optionally pretreated or hydrolyzed cellulosic or lignocellulosic material as the carbon source

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
DK17200641.3T 2010-06-29 2011-06-23 Polypeptid med beta-glucosidase-aktivitet og anvendelser deraf DK3318574T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US35959610P 2010-06-29 2010-06-29
EP10167776 2010-06-29
EP11729401.7A EP2588494B1 (en) 2010-06-29 2011-06-23 Polypeptide having beta-glucosidase activity and uses thereof

Publications (1)

Publication Number Publication Date
DK3318574T3 true DK3318574T3 (da) 2021-07-12

Family

ID=42562500

Family Applications (2)

Application Number Title Priority Date Filing Date
DK17200641.3T DK3318574T3 (da) 2010-06-29 2011-06-23 Polypeptid med beta-glucosidase-aktivitet og anvendelser deraf
DK11729401.7T DK2588494T3 (da) 2010-06-29 2011-06-23 Polypeptid med beta-glucosidaseaktivitet og anvendelser deraf

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK11729401.7T DK2588494T3 (da) 2010-06-29 2011-06-23 Polypeptid med beta-glucosidaseaktivitet og anvendelser deraf

Country Status (14)

Country Link
US (1) US9441214B2 (da)
EP (2) EP3318574B1 (da)
CN (1) CN102958939B (da)
AU (1) AU2011273688B2 (da)
BR (1) BR112012033699A2 (da)
CA (1) CA2803982A1 (da)
DK (2) DK3318574T3 (da)
EA (1) EA201300054A1 (da)
ES (1) ES2672125T3 (da)
HR (1) HRP20180854T1 (da)
HU (1) HUE037256T2 (da)
MX (1) MX2012015142A (da)
PL (1) PL2588494T3 (da)
WO (1) WO2012000890A1 (da)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011042437A2 (en) 2009-10-08 2011-04-14 Dsm Ip Assets B.V. Process for enzymatic hydrolysis of lignocellulosic material and fermentation of sugars
PL3659982T3 (pl) 2012-05-29 2021-01-11 Neozyme International, Inc. Kompozycja bio-katalityczna przydatna w kondycjonowaniu gleby
US10681914B2 (en) 2012-05-29 2020-06-16 Neozyme International, Inc. Non-toxic plant agent compositions and methods and uses thereof
US10557234B2 (en) 2012-05-29 2020-02-11 Neozyme International, Inc. Papermaking additive compositions and methods and uses thereof
US10334856B2 (en) 2012-05-29 2019-07-02 Neozyme International, Inc. Non-toxic pest control compositions and methods and uses thereof
CN102827820B (zh) * 2012-08-08 2013-09-25 天津工业生物技术研究所 一种β-葡糖苷酶及其应用
WO2014060380A1 (en) * 2012-10-16 2014-04-24 Dsm Ip Assets B.V. Cell wall deconstruction enzymes of thermoascus aurantiacus and uses thereof
WO2014138983A1 (en) * 2013-03-14 2014-09-18 Concordia University Novel cell wall deconstruction enzymes of malbranchea cinnamomea, thielavia australiensis, and paecilomyces byssochlamydoides, and uses thereof
WO2014140165A1 (en) * 2013-03-14 2014-09-18 Dsm Ip Assets B.V. Cell wall deconstruction enzymes of paecilomyces byssochlamydoides and uses thereof
WO2014202623A2 (en) * 2013-06-19 2014-12-24 Dsm Ip Assets B.V. Rasamsonia gene and use thereof
DK3166419T3 (da) * 2014-07-11 2019-12-09 Danisco Us Inc Paenibacillus-og bacillus spp. mannanaser
SG10202107085TA (en) 2015-04-10 2021-08-30 Comet Biorefining Inc Methods and compositions for the treatment of cellulosic biomass and products produced thereby
AU2016311181C1 (en) * 2015-08-22 2019-05-02 Neozyme International, Inc. Papermaking additive compositions and methods and uses thereof
CN108884481A (zh) * 2015-12-10 2018-11-23 帝斯曼知识产权资产管理有限公司 β-葡糖苷酶及其用途
US10808235B2 (en) 2015-12-10 2020-10-20 Dsm Ip Assets B.V. Beta-glucosidase and uses thereof
US20190002859A1 (en) * 2015-12-10 2019-01-03 Dsm Ip Assets B.V. Beta-glucosidase and uses thereof
US10913938B2 (en) 2016-07-29 2021-02-09 Dsm Ip Assets B.V. Polypeptides having cellulolytic enhancing activity and uses thereof
BR112020007246A2 (pt) 2017-10-30 2020-10-13 Dsm Ip Assets B.V. processo para hidrólise enzimática de material lignocelulósico e fermentação de açúcares
WO2019086370A1 (en) 2017-10-30 2019-05-09 Dsm Ip Assets B.V. Process for enzymatic hydrolysis of lignocellulosic material and fermentation of sugars
WO2019185681A1 (en) 2018-03-28 2019-10-03 Dsm Ip Assets B.V. Enzyme composition
BR112020018791A2 (pt) 2018-03-28 2020-10-13 Dsm Ip Assets B.V. composição de enzima
US10633461B2 (en) 2018-05-10 2020-04-28 Comet Biorefining Inc. Compositions comprising glucose and hemicellulose and their use
CN112204151B (zh) * 2018-05-30 2024-06-11 维尔萨利斯股份公司 从碳水化合物材料产生糖的方法
WO2020058253A1 (en) 2018-09-18 2020-03-26 Dsm Ip Assets B.V. Process for enzymatic hydrolysis of carbohydrate material and fermentation of sugars
WO2020058248A1 (en) 2018-09-18 2020-03-26 Dsm Ip Assets B.V. Process for enzymatic hydrolysis of carbohydrate material and fermentation of sugars
WO2020058249A1 (en) 2018-09-18 2020-03-26 Dsm Ip Assets B.V. Process for enzymatic hydrolysis of carbohydrate material and fermentation of sugars
EP3870715A1 (en) 2018-10-24 2021-09-01 DSM IP Assets B.V. Process for enzymatic hydrolysis of carbohydrate material and fermentation of sugars
US20220186264A1 (en) 2019-03-12 2022-06-16 Dsm Ip Assets B.V. Process for producing a fermentation broth
CN114391041A (zh) 2019-09-10 2022-04-22 帝斯曼知识产权资产管理有限公司 酶组合物
EP4142522A4 (en) 2020-04-26 2024-04-24 Neozyme Inernational, Inc. DRY POWDER COMPOSITIONS AND METHODS AND USES THEREOF
WO2021248137A2 (en) * 2020-06-05 2021-12-09 The Board Of Trustees Of The Leland Stanford Junior University Methods and systems to secrete lignin-modifying enzymes and uses thereof
CN112535235B (zh) * 2020-12-02 2022-08-02 上海健者有方健康科技发展有限公司 一种利用利马豆制备活性多肽的方法
BR112023020448A2 (pt) 2021-04-06 2023-11-21 Dsm Ip Assets Bv Composição enzimática
EP4320258A1 (en) 2021-04-06 2024-02-14 DSM IP Assets B.V. Enzyme composition
WO2022214457A1 (en) 2021-04-06 2022-10-13 Dsm Ip Assets B.V. Enzyme composition
MX2023010968A (es) 2021-04-08 2023-09-27 Versalis Spa Proceso para la preparacion de un producto de azucar y un producto de fermentacion.

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE3991T1 (de) 1979-10-26 1983-07-15 Schering Aktiengesellschaft Berlin Und Bergkamen Verfahren zur herstellung von 9-alpha-hydroxy-4- androsten-3,17-dion.
US6103464A (en) 1990-12-10 2000-08-15 Genencor International, Inc. Method of detecting DNA encoding a β-glucosidase from a filamentous fungus
EP1321523A3 (en) 1993-07-23 2004-03-03 DSM IP Assets B.V. Selection marker gene free recombinant strains; a method for obtaining them and the use of these strains
US5602004A (en) 1994-07-20 1997-02-11 Novo Nordisk Biotech, Inc. Thermophilic fungal expression system
US6015703A (en) 1998-03-10 2000-01-18 Iogen Corporation Genetic constructs and genetically modified microbes for enhanced production of beta-glucosidase
CN100529096C (zh) 1998-12-23 2009-08-19 诺维信公司 在曲霉属突变细胞中产生多肽的方法
AU7288100A (en) 1999-09-17 2001-04-24 Dsm N.V. Regulation of secondary metabolite production
CA2403842C (en) 2000-03-24 2012-09-25 Genencor International, Inc. Increased production of secreted proteins by recombinant eukaryotic cells
FR2826470B1 (fr) 2001-06-26 2003-09-19 Astrium Sas Procede et dispositif de pilotage de l'attitude et de guidage d'un satellite par grappe de gyrodynes
DK1409667T4 (da) 2001-07-23 2009-09-07 Dsm Ip Assets Bv Fremgangsm der til at fremstilling varierende polynucleotider
AU2003303934A1 (en) 2002-05-30 2004-09-09 Dsm Ip Assets B.V. Novel pectinases and uses thereof
DE60329018D1 (de) 2002-12-19 2009-10-08 Dsm Ip Assets Bv Neues herstellungsverfahren von lebensmitteln
CN1836033A (zh) 2003-02-05 2006-09-20 帝斯曼知识产权资产管理有限公司 草酸缺陷型Aspergillus Niger菌株生产多肽的用途
JP4638418B2 (ja) 2003-03-31 2011-02-23 ノボザイムス，インコーポレイティド アスペルギラス・ニガーの酵素−欠失変異体における生物学的物質の生成方法
WO2005059149A2 (en) 2003-12-12 2005-06-30 Chromagenics B.V. Improved protein production
US7413882B2 (en) 2004-03-25 2008-08-19 Novozymes, Inc. Methods for degrading or converting plant cell wall polysaccharides
US9243043B2 (en) 2004-04-02 2016-01-26 Dsm Ip Assets B.V. Filamentous fungal mutants with improved homologous recombination efficiency
AU2005254734B9 (en) 2004-06-16 2011-10-13 Dsm Ip Assets B.V. Production of polypeptides by improved secretion
US7888489B2 (en) 2005-01-24 2011-02-15 Dsm Ip Assets B.V. Method for producing a compound of interest in a filamentous fungal cell
IES20060090A2 (en) 2006-02-10 2007-06-13 Nat Univ Ireland Talaromyces emersonii enzyme systems
DE602007012846D1 (de) 2006-04-08 2011-04-14 Dsm Ip Assets Bv Verbessertes verfahren zur homologen rekombination in eukaryontischen zellen
BRPI0908879B1 (pt) * 2008-02-29 2019-07-09 University Of Central Florida Research Foundation, Inc. Método de degradação de planta, coquetel de degradação de plantas, material de planta homogeneizado e coquetel de enzimas
CN102482656A (zh) 2008-08-29 2012-05-30 埃欧金能源公司 具有提高的稳定性的经修饰的β-糖苷酶
EP2379712B1 (en) * 2008-12-19 2017-02-22 Novozymes Inc. Methods for increasing hydrolysis of cellulosic material in the presence of cellobiose dehydrogenase
AU2010317063B2 (en) * 2009-11-04 2014-10-23 Dsm Ip Assets B.V. Talaromyces transformants
DK3222716T3 (da) * 2009-11-06 2020-11-16 Novozymes Inc Sammensætninger til saccharificering af cellulosemateriale

Also Published As

Publication number Publication date
CN102958939A (zh) 2013-03-06
US9441214B2 (en) 2016-09-13
EP3318574B1 (en) 2021-04-21
PL2588494T3 (pl) 2018-08-31
MX2012015142A (es) 2013-05-01
DK2588494T3 (da) 2018-06-14
EP3318574A1 (en) 2018-05-09
BR112012033699A2 (pt) 2016-10-11
WO2012000890A1 (en) 2012-01-05
US20130104264A1 (en) 2013-04-25
CN102958939B (zh) 2016-02-03
EA201300054A1 (ru) 2013-05-30
HRP20180854T1 (hr) 2018-06-29
HUE037256T2 (hu) 2018-08-28
CA2803982A1 (en) 2012-01-05
AU2011273688A1 (en) 2013-01-17
AU2011273688B2 (en) 2014-10-30
ES2672125T3 (es) 2018-06-12
EP2588494B1 (en) 2018-03-07
EP2588494A1 (en) 2013-05-08

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