DK330783A - Fremgangsmaade til fremstilling af furanonderivater - Google Patents

Fremgangsmaade til fremstilling af furanonderivater Download PDF

Info

Publication number
DK330783A
DK330783A DK330783A DK330783A DK330783A DK 330783 A DK330783 A DK 330783A DK 330783 A DK330783 A DK 330783A DK 330783 A DK330783 A DK 330783A DK 330783 A DK330783 A DK 330783A
Authority
DK
Denmark
Prior art keywords
hydrogen
group
halogen atom
compounds
present
Prior art date
Application number
DK330783A
Other languages
Danish (da)
English (en)
Other versions
DK330783D0 (da
Inventor
Masanori Okamoto
Itsuo Uchida
Kazuyoshi Umehara
Masanobu Kohsaka
Hiroshi Imanaka
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Publication of DK330783D0 publication Critical patent/DK330783D0/da
Publication of DK330783A publication Critical patent/DK330783A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/12Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/12Ophthalmic agents for cataracts
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00Ethers; Compounds having groups, groups or groups
    • C07C43/02Ethers
    • C07C43/03Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/14Unsaturated ethers
    • C07C43/164Unsaturated ethers containing six-membered aromatic rings
    • C07C43/166Unsaturated ethers containing six-membered aromatic rings having unsaturation outside the aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32Oxygen atoms
    • C07D307/33Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/58One oxygen atom, e.g. butenolide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/60Two oxygen atoms, e.g. succinic anhydride
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10Oxygen atoms
    • C07D309/12Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14Fungi; Culture media therefor
    • C12N1/145Fungal isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02Oxygen as only ring hetero atoms
    • C12P17/04Oxygen as only ring hetero atoms containing a five-membered hetero ring, e.g. griseofulvin, vitamin C
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/645Fungi ; Processes using fungi
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK330783A 1982-07-19 1983-07-18 Fremgangsmaade til fremstilling af furanonderivater DK330783A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP57126599A JPS5916884A (ja) 1982-07-19 1982-07-19 新規フラン化合物

Publications (2)

Publication Number Publication Date
DK330783D0 DK330783D0 (da) 1983-07-18
DK330783A true DK330783A (da) 1984-03-05

Family

ID=14939171

Family Applications (1)

Application Number Title Priority Date Filing Date
DK330783A DK330783A (da) 1982-07-19 1983-07-18 Fremgangsmaade til fremstilling af furanonderivater

Country Status (9)

Country Link
US (2) US4585789A (es)
EP (1) EP0099692B1 (es)
JP (1) JPS5916884A (es)
KR (1) KR840005439A (es)
AT (1) ATE25977T1 (es)
CA (1) CA1221929A (es)
DE (1) DE3370327D1 (es)
DK (1) DK330783A (es)
ES (5) ES8600263A1 (es)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5916884A (ja) * 1982-07-19 1984-01-28 Fujisawa Pharmaceut Co Ltd 新規フラン化合物
EP0189272A3 (en) * 1985-01-17 1987-08-19 Fujisawa Pharmaceutical Co., Ltd. New furanone derivatives, processes for preparation thereof and use thereof
US4707499A (en) * 1985-12-02 1987-11-17 G. D. Searle & Co. 3-alkyl-5-(substituted amino)methyl)dihydro-3-phenyl-2(3H)-furanones and imino analogs thereof used for treatment of arrhythmia
DE3615157A1 (de) * 1986-05-05 1987-11-12 Schwabe Willmar Gmbh & Co 5-arylalkyl-4-alkoxy-2(5h)-furanone, zwischenprodukte und verfahren zu ihrer herstellung sowie ihre anwendung als therapeutische wirkstoffe
US4909957A (en) * 1987-09-07 1990-03-20 Daiso Co., Ltd. Liquid crystalline compounds and process for production thereof
JPH0222271A (ja) * 1988-07-11 1990-01-25 Kuraray Co Ltd 共役γ−オキシブテノライド化合物およびこれを有効成分とする抗潰瘍剤
JP2790335B2 (ja) * 1989-09-20 1998-08-27 株式会社クラレ 共役γ―オキシブテノライド化合物およびこれを有効成分とする抗潰瘍剤
DE4014420A1 (de) * 1989-09-23 1991-04-04 Bayer Ag 5h-furan-2-on-derivate
JP3068706B2 (ja) * 1992-02-26 2000-07-24 塩野義製薬株式会社 アルド−ス還元酵素阻害物質
US6492413B2 (en) 1993-01-15 2002-12-10 G.D. Searle & Co. 3.4-diaryl thiophenes and analogs thereof having use as antiinflammatory agents
US5474995A (en) * 1993-06-24 1995-12-12 Merck Frosst Canada, Inc. Phenyl heterocycles as cox-2 inhibitors
KR960703901A (ko) * 1993-08-19 1996-08-31 로즈 암스트롱 치환된 2(5H)푸라논, 2(5H)티오페논 및 2(5H)피롤론 유도체, 그의 제조 방법 및 엔도텔린 길항제로서의 그의 용도(Substituted 2(5H)Furanone, 2(5H)Thiophenone and 2(5H)Pyrrolone Derivatives, Their Preparation and Their Use as Endothelin antagonists)
US5698585A (en) 1995-04-13 1997-12-16 Kikkoman Corporation Pharmaceutical preparation for prevention and/or treatment for cataract
US5922759A (en) * 1996-06-21 1999-07-13 Warner-Lambert Company Butenolide endothelin antagonists
WO1997008169A1 (en) * 1995-08-24 1997-03-06 Warner-Lambert Company Furanone endothelin antagonists
GB9615867D0 (en) * 1996-07-03 1996-09-11 Merck & Co Inc Process of preparing phenyl heterocycles useful as cox-2 inhibitors
US5891892A (en) * 1996-10-29 1999-04-06 Warner-Lambert Company Small molecule biaryl compounds as inhibitors of endothelin converting enzyme
US6355593B1 (en) 2000-09-01 2002-03-12 Exxonmobil Research And Engineering Company Fischer-Tropsch catalyst enhancement
US6753351B2 (en) 2002-01-29 2004-06-22 Exxonmobil Research And Engineering Company Supported catalyst activation
US7419928B2 (en) * 2003-04-11 2008-09-02 Exxonmobil Research And Engineering Company Fischer-Tropsch catalyst production
US7361619B2 (en) * 2003-04-11 2008-04-22 Exxonmobil Research And Engineering Company Fischer-Tropsch catalyst production
EP2746266A1 (en) * 2012-12-19 2014-06-25 Basf Se New substituted triazoles and imidazoles and their use as fungicides

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2841594A (en) * 1958-07-01 Production of beta-furoic acids
US3113939A (en) * 1959-05-28 1963-12-10 Du Pont Substituted maleic anhydrides and the corresponding lactones of 3-formylacrylic acid
US3509209A (en) * 1967-01-12 1970-04-28 Union Oil Co Hydrocarboxylation of certain conjugated diolefin compounds
US3873575A (en) * 1967-02-17 1975-03-25 Spofa Vereinigte Pharma Werke {65 -4-N-butoxyphenyl-{60 ,{62 -dibromo-{66 {300 ,{330 -crotonic acid lactone
US3564020A (en) * 1968-07-17 1971-02-16 Union Oil Co Preparation of angelica lactone
GB1228185A (es) * 1968-09-17 1971-04-15
US3813416A (en) * 1969-02-17 1974-05-28 Mobil Oil Corp Substituted gamma-butyrolactones derived from c16 and greater unsaturated acids
DE1920176A1 (de) * 1969-04-21 1970-10-22 Thomae Gmbh Dr K Neues Verfahren zur Herstellung von Hydroxycrotonsaeurelaktonen
US3838168A (en) * 1969-11-21 1974-09-24 Dow Chemical Co Alpha-methylenation of gamma-butyrolactones
US3826839A (en) * 1970-12-03 1974-07-30 Smithkline Corp Anti-arthritic compositions comprising ester derivatives of pulvinic acid and methods of producing anti-arthritic activity
US3940424A (en) * 1973-12-19 1976-02-24 Monsanto Company Lactones
US4010170A (en) * 1975-09-24 1977-03-01 Iowa State University Research Foundation, Inc. Butenolide synthesis via carbonylation of vinylmercurials
US4214092A (en) * 1979-02-21 1980-07-22 Iowa State University Research Foundation, Inc. Rearrangement of acyloxy furans and thiophenes prepared from butenolides
FR2456097A1 (fr) * 1979-05-07 1980-12-05 Delalande Sa Nouveaux derives de la 5 h-furanone-2 et de la 3 h-dihydrofuranone-2, leur procede de preparation et leur application en therapeutique
US4508914A (en) * 1979-12-22 1985-04-02 Dynamit Nobel Ag 3H-Furanones
JPS5916884A (ja) * 1982-07-19 1984-01-28 Fujisawa Pharmaceut Co Ltd 新規フラン化合物

Also Published As

Publication number Publication date
DK330783D0 (da) 1983-07-18
US4585789A (en) 1986-04-29
ES530709A0 (es) 1985-05-16
ES8604552A1 (es) 1986-02-01
ES524274A0 (es) 1985-05-01
ES8600401A1 (es) 1985-05-16
ES530710A0 (es) 1986-02-01
ES8600263A1 (es) 1985-05-01
ES8604551A1 (es) 1986-02-01
JPS5916884A (ja) 1984-01-28
CA1221929A (en) 1987-05-19
EP0099692B1 (en) 1987-03-18
KR840005439A (ko) 1984-11-12
ATE25977T1 (de) 1987-04-15
ES530708A0 (es) 1986-02-01
US4797417A (en) 1989-01-10
DE3370327D1 (en) 1987-04-23
EP0099692A1 (en) 1984-02-01
ES530707A0 (es) 1985-05-16
JPH0352458B2 (es) 1991-08-12
ES8600264A1 (es) 1985-05-16

Similar Documents

Publication Publication Date Title
DK330783A (da) Fremgangsmaade til fremstilling af furanonderivater
ES8506001A1 (es) Un procedimiento para preparar compuestos de imidazol fusionados
DE3462250D1 (en) Thioethers, process for their preparation and medicines containing these compounds
AR012878A1 (es) Un compuesto derivado de 5'-desoxicitidina, su uso, un proceso para fabricarlo, composiciones farmaceuticas que lo comprende, y un kit que comprende dicha composicion.
KR880007070A (ko) 백내장 치료용 약학 조성물
EA199900460A1 (ru) Производные бензолсульфоамида и лекарственные средства, содержащие упомянутые производные
ES528459A0 (es) Procedimiento de preparacion de nuevos derivados 1-hidroxipropil resorcinos provistos de un grupo fenilo sustituidos.
ATE16383T1 (de) Neue heteroaryloxypropanolamine, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel.
DE3269505D1 (en) Substituted 1-benzoyl-2-phenylimino-imidazolidines, their acid addition salts, process for their preparation and pharmaceutical compositions containing them
GB2071098B (en) Dibenzocycloheptenylidenes and antiinflammatory compositions
ES528458A0 (es) Procedimiento de preparacion de nuevos derivados 4-hidroxi- -etil-benzoles
DK232883A (da) Fremgangsmaade til fremstilling af optisk aktive imidazolylpropanolforbindelser
GB1557420A (en) Preparation of isobutyramide derivatives
SE7907656L (sv) 3,4-dihydroxikanelaldehydderivat
AU547599B2 (en) Tricyclic compounds
MC1555A1 (fr) Dérivés de l'acridanone
ES493044A0 (es) Un procedimiento para la preparacion de agentes antibacterianos beta-lactanicos.
ES464875A1 (es) Un procedimiento para la preparacion de nuevos compuestos tetraciclicos

Legal Events

Date Code Title Description
AHB Application shelved due to non-payment