DK3302551T3 - Fremgangsmåder til behandling af HER2-positiv tidligere ubehandlet metastatisk brystkræft - Google Patents
Fremgangsmåder til behandling af HER2-positiv tidligere ubehandlet metastatisk brystkræft Download PDFInfo
- Publication number
- DK3302551T3 DK3302551T3 DK16730123.3T DK16730123T DK3302551T3 DK 3302551 T3 DK3302551 T3 DK 3302551T3 DK 16730123 T DK16730123 T DK 16730123T DK 3302551 T3 DK3302551 T3 DK 3302551T3
- Authority
- DK
- Denmark
- Prior art keywords
- her2
- approaches
- treatment
- breast cancer
- metastatic breast
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
- A61K47/6851—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell
- A61K47/6855—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell the tumour determinant being from breast cancer cell
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
- A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
- A61K47/68033—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a maytansine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/32—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- A61K2039/507—Comprising a combination of two or more separate antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Organic Chemistry (AREA)
- Cell Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562168809P | 2015-05-30 | 2015-05-30 | |
| PCT/US2016/034835 WO2016196373A2 (en) | 2015-05-30 | 2016-05-27 | Methods of treating her2-positive metastatic breast cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3302551T3 true DK3302551T3 (da) | 2024-08-26 |
Family
ID=56134616
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK16730123.3T DK3302551T3 (da) | 2015-05-30 | 2016-05-27 | Fremgangsmåder til behandling af HER2-positiv tidligere ubehandlet metastatisk brystkræft |
Country Status (15)
| Country | Link |
|---|---|
| US (3) | US11406715B2 (enExample) |
| EP (1) | EP3302551B1 (enExample) |
| JP (4) | JP6822980B2 (enExample) |
| CN (2) | CN121971642A (enExample) |
| DK (1) | DK3302551T3 (enExample) |
| ES (1) | ES2984592T3 (enExample) |
| FI (1) | FI3302551T3 (enExample) |
| HR (1) | HRP20241134T1 (enExample) |
| HU (1) | HUE068105T2 (enExample) |
| LT (1) | LT3302551T (enExample) |
| PL (1) | PL3302551T3 (enExample) |
| PT (1) | PT3302551T (enExample) |
| RS (1) | RS65871B1 (enExample) |
| SI (1) | SI3302551T1 (enExample) |
| WO (1) | WO2016196373A2 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20210330801A1 (en) * | 2017-03-02 | 2021-10-28 | Cadila Healthcare Limited | Novel protein drug conjugate formulation |
| US20200114018A1 (en) * | 2018-10-15 | 2020-04-16 | Genentech, Inc. | Methods of treating residual breast cancer with trastuzumab emtansine |
| MA53933A (fr) | 2018-10-21 | 2021-08-25 | Slsg Ltd Llc | Poly-immunothérapie pour le traitement du cancer du sein triple-négatif |
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-
2016
- 2016-05-27 JP JP2017561971A patent/JP6822980B2/ja active Active
- 2016-05-27 LT LTEPPCT/US2016/034835T patent/LT3302551T/lt unknown
- 2016-05-27 CN CN202511623386.6A patent/CN121971642A/zh active Pending
- 2016-05-27 FI FIEP16730123.3T patent/FI3302551T3/fi active
- 2016-05-27 RS RS20240909A patent/RS65871B1/sr unknown
- 2016-05-27 US US15/576,593 patent/US11406715B2/en active Active
- 2016-05-27 SI SI201631844T patent/SI3302551T1/sl unknown
- 2016-05-27 WO PCT/US2016/034835 patent/WO2016196373A2/en not_active Ceased
- 2016-05-27 HR HRP20241134TT patent/HRP20241134T1/hr unknown
- 2016-05-27 PT PT167301233T patent/PT3302551T/pt unknown
- 2016-05-27 ES ES16730123T patent/ES2984592T3/es active Active
- 2016-05-27 EP EP16730123.3A patent/EP3302551B1/en active Active
- 2016-05-27 PL PL16730123.3T patent/PL3302551T3/pl unknown
- 2016-05-27 DK DK16730123.3T patent/DK3302551T3/da active
- 2016-05-27 HU HUE16730123A patent/HUE068105T2/hu unknown
- 2016-05-27 CN CN201680031816.8A patent/CN107614015A/zh active Pending
-
2021
- 2021-01-07 JP JP2021001246A patent/JP7330217B2/ja active Active
-
2022
- 2022-07-19 US US17/813,466 patent/US20220354961A1/en not_active Abandoned
-
2023
- 2023-04-11 JP JP2023064033A patent/JP2023100635A/ja not_active Withdrawn
-
2025
- 2025-06-23 JP JP2025105921A patent/JP2025157247A/ja active Pending
- 2025-08-01 US US19/288,035 patent/US20260199508A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP3302551B1 (en) | 2024-06-26 |
| LT3302551T (lt) | 2024-09-10 |
| HUE068105T2 (hu) | 2024-12-28 |
| WO2016196373A2 (en) | 2016-12-08 |
| JP2025157247A (ja) | 2025-10-15 |
| JP2023100635A (ja) | 2023-07-19 |
| PT3302551T (pt) | 2024-08-21 |
| US20220354961A1 (en) | 2022-11-10 |
| HRP20241134T1 (hr) | 2024-11-22 |
| RS65871B1 (sr) | 2024-09-30 |
| PL3302551T3 (pl) | 2024-09-30 |
| JP6822980B2 (ja) | 2021-01-27 |
| FI3302551T3 (fi) | 2024-08-27 |
| JP7330217B2 (ja) | 2023-08-21 |
| ES2984592T3 (es) | 2024-10-30 |
| SI3302551T1 (sl) | 2024-10-30 |
| JP2021073203A (ja) | 2021-05-13 |
| US20190030181A1 (en) | 2019-01-31 |
| CN121971642A (zh) | 2026-05-05 |
| CN107614015A (zh) | 2018-01-19 |
| JP2018516920A (ja) | 2018-06-28 |
| US20260199508A1 (en) | 2026-07-16 |
| WO2016196373A3 (en) | 2017-02-02 |
| WO2016196373A8 (en) | 2017-11-30 |
| US11406715B2 (en) | 2022-08-09 |
| EP3302551A2 (en) | 2018-04-11 |
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