DK3297750T3 - Fremgangsmåder og apparat til dannelse af åbninger i en faststofmembran under anvendelse af dielektrisk gennemslag - Google Patents

Fremgangsmåder og apparat til dannelse af åbninger i en faststofmembran under anvendelse af dielektrisk gennemslag Download PDF

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Publication number
DK3297750T3
DK3297750T3 DK16727070.1T DK16727070T DK3297750T3 DK 3297750 T3 DK3297750 T3 DK 3297750T3 DK 16727070 T DK16727070 T DK 16727070T DK 3297750 T3 DK3297750 T3 DK 3297750T3
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methods
forming openings
solid membrane
dielectric
impact
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DK16727070.1T
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English (en)
Inventor
Ping Xie
Ken Healy
Justin Millis
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Oxford Nanopore Tech Ltd
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D67/00Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
    • B01D67/0039Inorganic membrane manufacture
    • B01D67/0053Inorganic membrane manufacture by inducing porosity into non porous precursor membranes
    • B01D67/006Inorganic membrane manufacture by inducing porosity into non porous precursor membranes by elimination of segments of the precursor, e.g. nucleation-track membranes, lithography or laser methods
    • B01D67/0062Inorganic membrane manufacture by inducing porosity into non porous precursor membranes by elimination of segments of the precursor, e.g. nucleation-track membranes, lithography or laser methods by micromachining techniques, e.g. using masking and etching steps, photolithography
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D69/00Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
    • B01D69/02Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor characterised by their properties
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D69/00Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
    • B01D69/12Composite membranes; Ultra-thin membranes
    • B01D69/1214Chemically bonded layers, e.g. cross-linking
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869Methods for sequencing
    • CCHEMISTRY; METALLURGY
    • C25ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25FPROCESSES FOR THE ELECTROLYTIC REMOVAL OF MATERIALS FROM OBJECTS; APPARATUS THEREFOR
    • C25F3/00Electrolytic etching or polishing
    • C25F3/02Etching
    • CCHEMISTRY; METALLURGY
    • C25ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25FPROCESSES FOR THE ELECTROLYTIC REMOVAL OF MATERIALS FROM OBJECTS; APPARATUS THEREFOR
    • C25F3/00Electrolytic etching or polishing
    • C25F3/02Etching
    • C25F3/14Etching locally
    • CCHEMISTRY; METALLURGY
    • C25ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25FPROCESSES FOR THE ELECTROLYTIC REMOVAL OF MATERIALS FROM OBJECTS; APPARATUS THEREFOR
    • C25F7/00Constructional parts, or assemblies thereof, of cells for electrolytic removal of material from objects; Servicing or operating
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/48707Physical analysis of biological material of liquid biological material by electrical means
    • G01N33/48721Investigating individual macromolecules, e.g. by translocation through nanopores
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D2323/00Details relating to membrane preparation
    • B01D2323/42Details of membrane preparation apparatus
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D2325/00Details relating to properties of membranes
    • B01D2325/02Details relating to pores or porosity of the membranes
    • B01D2325/021Pore shapes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D2325/00Details relating to properties of membranes
    • B01D2325/06Surface irregularities
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y40/00Manufacture or treatment of nanostructures

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  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Electrochemistry (AREA)
  • Materials Engineering (AREA)
  • Metallurgy (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Manufacturing & Machinery (AREA)
  • Inorganic Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Pathology (AREA)
  • Nanotechnology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Micromachines (AREA)
  • Semiconductor Integrated Circuits (AREA)
DK16727070.1T 2015-05-20 2016-05-20 Fremgangsmåder og apparat til dannelse af åbninger i en faststofmembran under anvendelse af dielektrisk gennemslag DK3297750T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1508669.7A GB201508669D0 (en) 2015-05-20 2015-05-20 Methods and apparatus for forming apertures in a solid state membrane using dielectric breakdown
PCT/US2016/033487 WO2016187519A1 (en) 2015-05-20 2016-05-20 Methods and apparatus for forming apertures in a solid state membrane using dielectric breakdown

Publications (1)

Publication Number Publication Date
DK3297750T3 true DK3297750T3 (da) 2021-06-14

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Family Applications (1)

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DK16727070.1T DK3297750T3 (da) 2015-05-20 2016-05-20 Fremgangsmåder og apparat til dannelse af åbninger i en faststofmembran under anvendelse af dielektrisk gennemslag

Country Status (7)

Country Link
US (3) US10596523B2 (da)
EP (2) EP3297750B1 (da)
JP (1) JP6937986B2 (da)
CN (2) CN107810048B (da)
DK (1) DK3297750T3 (da)
GB (1) GB201508669D0 (da)
WO (1) WO2016187519A1 (da)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201202519D0 (en) 2012-02-13 2012-03-28 Oxford Nanopore Tech Ltd Apparatus for supporting an array of layers of amphiphilic molecules and method of forming an array of layers of amphiphilic molecules
EP4293349A3 (en) 2015-02-05 2024-02-21 President and Fellows of Harvard College Nanopore sensor including fluidic passage
GB201508669D0 (en) 2015-05-20 2015-07-01 Oxford Nanopore Tech Ltd Methods and apparatus for forming apertures in a solid state membrane using dielectric breakdown
GB201611770D0 (en) 2016-07-06 2016-08-17 Oxford Nanopore Tech Microfluidic device
GB201612458D0 (en) 2016-07-14 2016-08-31 Howorka Stefan And Pugh Genevieve Membrane spanning DNA nanopores for molecular transport
GB201707138D0 (en) 2017-05-04 2017-06-21 Oxford Nanopore Tech Ltd Machine learning analysis of nanopore measurements
US10752496B2 (en) * 2017-09-22 2020-08-25 Applied Materials, Inc. Pore formation in a substrate
GB2574048B (en) 2018-05-24 2021-06-16 Oxford Nanopore Tech Ltd Nanopore sensor component with electrostatic discharge protection
GB201812615D0 (en) 2018-08-02 2018-09-19 Ucl Business Plc Membrane bound nucleic acid nanopores
GB201814369D0 (en) 2018-09-04 2018-10-17 Oxford Nanopore Tech Ltd Method for determining a polymersequence
US11454624B2 (en) 2018-09-28 2022-09-27 Ofer Wilner Nanopore technologies
GB201819378D0 (en) 2018-11-28 2019-01-09 Oxford Nanopore Tech Ltd Analysis of nanopore signal using a machine-learning technique
WO2020183172A1 (en) 2019-03-12 2020-09-17 Oxford Nanopore Technologies Inc. Nanopore sensing device and methods of operation and of forming it
GB201907243D0 (en) 2019-05-22 2019-07-03 Oxford Nanopore Tech Ltd Sensing interactions between molecular entities and nanapores
JP2023530965A (ja) * 2020-06-17 2023-07-20 ナノペック, インコーポレイテッド 高密度バイオアッセイ多重化アレイのためのナノ多孔質セラミックフィルム
US20220054986A1 (en) * 2020-07-17 2022-02-24 Microcontinuum, Inc. Filtration Films Having Dense Packing of Pores of Uniform Size and Distribution, and Tools and Methods for Their Formation
WO2022020461A1 (en) 2020-07-22 2022-01-27 Oxford Nanopore Technologies Inc. Solid state nanopore formation
WO2022211951A1 (en) * 2021-03-31 2022-10-06 Illumina, Inc. Nanopore sensor devices
CN113363140B (zh) * 2021-06-02 2023-03-28 南方科技大学 生物掩膜版以及在衬底上图案化的方法
GB202108820D0 (en) 2021-06-18 2021-08-04 Ucl Business Ltd Nucleic acid nanopore with enhanced sensing functionality
GB202108821D0 (en) 2021-06-18 2021-08-04 Ucl Business Ltd Nanomechanically actuated nucleic acid nanopore
US20240272138A1 (en) 2021-06-18 2024-08-15 Ucl Business Ltd Nucleic acid nanopore with enhanced sensing functionality
JPWO2023021627A1 (da) * 2021-08-18 2023-02-23
WO2023094806A1 (en) 2021-11-29 2023-06-01 Oxford Nanopore Technologies Plc Nanopore measurement signal analysis
GB202118908D0 (en) 2021-12-23 2022-02-09 Oxford Nanopore Tech Ltd Method
GB202118906D0 (en) 2021-12-23 2022-02-09 Oxford Nanopore Tech Ltd Method
CN114950589B (zh) * 2022-05-27 2024-02-09 复旦大学 一种mct/aao异质超薄膜在光控双向可调控离子传输的应用
GB202216162D0 (en) 2022-10-31 2022-12-14 Oxford Nanopore Tech Plc Method
WO2024094966A1 (en) 2022-11-01 2024-05-10 Oxford Nanopore Technologies Plc Biochemical analysis system and method of controlling a biochemical analysis system
GB202307486D0 (en) 2023-05-18 2023-07-05 Oxford Nanopore Tech Plc Method
GB202401864D0 (en) 2024-02-12 2024-03-27 Fund Centre De Regulacio Genòmica A method of detecting non-canonical bases in sequencing data

Family Cites Families (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6267872B1 (en) 1998-11-06 2001-07-31 The Regents Of The University Of California Miniature support for thin films containing single channels or nanopores and methods for using same
US6627067B1 (en) 1999-06-22 2003-09-30 President And Fellows Of Harvard College Molecular and atomic scale evaluation of biopolymers
EP1402570B1 (en) 2001-06-27 2014-02-12 President and Fellows of Harvard College Control of solid state dimensional features
WO2005124888A1 (en) 2004-06-08 2005-12-29 President And Fellows Of Harvard College Suspended carbon nanotube field effect transistor
US20080020499A1 (en) * 2004-09-10 2008-01-24 Dong-Wook Kim Nanotube assembly including protective layer and method for making the same
CA2606440A1 (en) * 2005-04-29 2006-11-09 University Of Rochester Ultrathin porous nanoscale membranes, methods of making, and uses thereof
WO2007041621A2 (en) 2005-10-03 2007-04-12 Xingsheng Sean Ling Hybridization assisted nanopore sequencing
US20080113833A1 (en) 2006-11-15 2008-05-15 Francisco Fernandez Methods of playing soccer games
US20110121840A1 (en) 2007-02-20 2011-05-26 Gurdial Singh Sanghera Lipid Bilayer Sensor System
CA2684801C (en) 2007-04-04 2017-10-10 The Regents Of The University Of California Compositions, devices, systems, and methods for using a nanopore
EP3543357A1 (en) 2007-05-08 2019-09-25 Trustees of Boston University Chemical functionalization of solid-state nanopores and nanopore arrays and applications thereof
GB0713402D0 (en) 2007-07-11 2007-08-22 Cardiff & Vale Nhs Trust A method of diagnosing a condition using a neural network
EP2195648B1 (en) 2007-09-12 2019-05-08 President and Fellows of Harvard College High-resolution molecular graphene sensor comprising an aperture in the graphene layer
GB0724736D0 (en) 2007-12-19 2008-01-30 Oxford Nanolabs Ltd Formation of layers of amphiphilic molecules
AU2010240670B2 (en) 2009-04-20 2015-08-20 Oxford Nanopore Technologies Limited Lipid bilayer sensor array
CA2772789C (en) 2009-09-18 2018-10-30 President And Fellows Of Harvard College Bare single-layer graphene membrane having a nanopore enabling high-sensitivity molecular detection and analysis
WO2011040996A1 (en) 2009-09-30 2011-04-07 Quantapore, Inc. Ultrafast sequencing of biological polymers using a labeled nanopore
US9127313B2 (en) 2009-12-01 2015-09-08 Oxford Nanopore Technologies Limited Biochemical analysis instrument
US8828138B2 (en) 2010-05-17 2014-09-09 International Business Machines Corporation FET nanopore sensor
EP2580588B1 (en) 2010-06-08 2014-09-24 President and Fellows of Harvard College Nanopore device with graphene supported artificial lipid membrane
KR101267789B1 (ko) * 2010-06-25 2013-06-04 서울대학교산학협력단 나노 포어 구조를 이용한 dna 분석용 장치, 분석 방법 및 pcr 정량 검출 장치
AU2012229925B2 (en) 2011-03-15 2015-12-03 President And Fellows Of Harvard College Controlled fabrication of nanopores in nanometric solid state materials
US8981995B2 (en) * 2011-06-03 2015-03-17 Microsoft Technology Licensing, Llc. Low accuracy positional data by detecting improbable samples
US10761043B2 (en) 2011-07-22 2020-09-01 The Trustees Of The University Of Pennsylvania Graphene-based nanopore and nanostructure devices and methods for macromolecular analysis
US10175195B2 (en) 2011-07-27 2019-01-08 The Board Of Trustees Of The University Of Illinois Nanopore sensors for biomolecular characterization
EP2758545B1 (en) 2011-09-23 2017-07-26 Oxford Nanopore Technologies Limited Analysis of a polymer comprising polymer units
KR20140090633A (ko) 2011-10-21 2014-07-17 옥스포드 나노포어 테크놀로지즈 리미티드 포어 및 hel308 헬리카제를 사용하여 표적 폴리뉴클레오티드를 특성화하는 방법
AU2012360244B2 (en) 2011-12-29 2018-08-23 Oxford Nanopore Technologies Limited Enzyme method
US9617591B2 (en) 2011-12-29 2017-04-11 Oxford Nanopore Technologies Ltd. Method for characterising a polynucleotide by using a XPD helicase
JP6312607B2 (ja) 2012-02-16 2018-04-18 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 酵素仲介タンパク質トランスロケーションのためのナノポアセンサー
JP6226888B2 (ja) 2012-02-16 2017-11-08 オックスフォード ナノポール テクノロジーズ リミテッド ポリマーの測定の解析
CA2869753A1 (en) * 2012-04-09 2013-10-17 Jingyue Ju Method of preparation of nanopore and uses thereof
JP6271505B2 (ja) 2012-04-10 2018-01-31 オックスフォード ナノポール テクノロジーズ リミテッド 変異体ライセニンポア
BR112014027829B1 (pt) * 2012-05-07 2021-03-23 The University Of Ottawa Fabricação de nanoporos usando campos elétricos altos
US20140006308A1 (en) 2012-06-28 2014-01-02 Google Inc. Portion-by-portion feedback for electronic books
WO2014105246A2 (en) * 2012-10-05 2014-07-03 Massachusetts Institute Of Technology Nanofluidic sorting system for gene synthesis and pcr reaction products
GB201313121D0 (en) 2013-07-23 2013-09-04 Oxford Nanopore Tech Ltd Array of volumes of polar medium
US9656293B2 (en) * 2013-03-15 2017-05-23 President And Fellows Of Harvard College Fabrication of nanopores in atomically-thin membranes by ultra-short electrical pulsing
JP6209122B2 (ja) * 2014-04-02 2017-10-04 株式会社日立ハイテクノロジーズ 孔形成方法及び測定装置
CN114605507A (zh) 2014-09-01 2022-06-10 弗拉芒区生物技术研究所 突变csgg孔
US20170219523A1 (en) * 2014-10-01 2017-08-03 University Of Tasmania Extraction and concentration device
WO2016094131A2 (en) 2014-12-01 2016-06-16 Cornell University Nanopore-containing substrates with aligned nanoscale electronic elements and methods of making and using same
GB201508669D0 (en) 2015-05-20 2015-07-01 Oxford Nanopore Tech Ltd Methods and apparatus for forming apertures in a solid state membrane using dielectric breakdown

Also Published As

Publication number Publication date
GB201508669D0 (en) 2015-07-01
CN107810048A (zh) 2018-03-16
EP3741452A1 (en) 2020-11-25
US11986775B2 (en) 2024-05-21
US10596523B2 (en) 2020-03-24
EP3297750A1 (en) 2018-03-28
CN113274888A (zh) 2021-08-20
JP6937986B2 (ja) 2021-09-22
WO2016187519A1 (en) 2016-11-24
EP3297750B1 (en) 2021-04-07
US20180141007A1 (en) 2018-05-24
US20200179880A1 (en) 2020-06-11
JP2018527176A (ja) 2018-09-20
CN113274888B (zh) 2023-05-16
US20240299884A1 (en) 2024-09-12
CN107810048B (zh) 2020-11-10

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