DK3294856T3 - Proceskontrolsystem til regulering og styring af et modulært opbygget anlæg til produktion af biofarmaceutiske og biologiske makromolekylære produkter - Google Patents

Proceskontrolsystem til regulering og styring af et modulært opbygget anlæg til produktion af biofarmaceutiske og biologiske makromolekylære produkter Download PDF

Info

Publication number
DK3294856T3
DK3294856T3 DK16722163T DK16722163T DK3294856T3 DK 3294856 T3 DK3294856 T3 DK 3294856T3 DK 16722163 T DK16722163 T DK 16722163T DK 16722163 T DK16722163 T DK 16722163T DK 3294856 T3 DK3294856 T3 DK 3294856T3
Authority
DK
Denmark
Prior art keywords
regulation
plant
control system
biological macromolecular
process control
Prior art date
Application number
DK16722163T
Other languages
Danish (da)
English (en)
Inventor
Peter Schwan
Martin Lobedann
Jens Bernshausen
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=53177195&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK3294856(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Ag filed Critical Bayer Ag
Application granted granted Critical
Publication of DK3294856T3 publication Critical patent/DK3294856T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/44—Multiple separable units; Modules
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/58—Reaction vessels connected in series or in parallel
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/10—Perfusion
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/44—Means for regulation, monitoring, measurement or control, e.g. flow regulation of volume or liquid level
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/48—Automatic or computerized control
    • G—PHYSICS
    • G05—CONTROLLING; REGULATING
    • G05D—SYSTEMS FOR CONTROLLING OR REGULATING NON-ELECTRIC VARIABLES
    • G05D7/00—Control of flow
    • G05D7/06—Control of flow characterised by the use of electric means
    • G—PHYSICS
    • G05—CONTROLLING; REGULATING
    • G05B—CONTROL OR REGULATING SYSTEMS IN GENERAL; FUNCTIONAL ELEMENTS OF SUCH SYSTEMS; MONITORING OR TESTING ARRANGEMENTS FOR SUCH SYSTEMS OR ELEMENTS
    • G05B11/00—Automatic controllers
    • G05B11/01—Automatic controllers electric
    • G05B11/36—Automatic controllers electric with provision for obtaining particular characteristics, e.g. proportional, integral, differential
    • G05B11/42—Automatic controllers electric with provision for obtaining particular characteristics, e.g. proportional, integral, differential for obtaining a characteristic which is both proportional and time-dependent, e.g. P. I., P. I. D.
    • G—PHYSICS
    • G05—CONTROLLING; REGULATING
    • G05B—CONTROL OR REGULATING SYSTEMS IN GENERAL; FUNCTIONAL ELEMENTS OF SUCH SYSTEMS; MONITORING OR TESTING ARRANGEMENTS FOR SUCH SYSTEMS OR ELEMENTS
    • G05B13/00—Adaptive control systems, i.e. systems automatically adjusting themselves to have a performance which is optimum according to some preassigned criterion
    • G05B13/02—Adaptive control systems, i.e. systems automatically adjusting themselves to have a performance which is optimum according to some preassigned criterion electric
    • G05B13/0265—Adaptive control systems, i.e. systems automatically adjusting themselves to have a performance which is optimum according to some preassigned criterion electric the criterion being a learning criterion
    • G05B13/0275—Adaptive control systems, i.e. systems automatically adjusting themselves to have a performance which is optimum according to some preassigned criterion electric the criterion being a learning criterion using fuzzy logic only

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Computer Hardware Design (AREA)
  • General Physics & Mathematics (AREA)
  • Automation & Control Theory (AREA)
  • Artificial Intelligence (AREA)
  • Software Systems (AREA)
  • Medical Informatics (AREA)
  • Mathematical Physics (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Evolutionary Computation (AREA)
  • Fuzzy Systems (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Feedback Control In General (AREA)
  • Testing And Monitoring For Control Systems (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Flow Control (AREA)
DK16722163T 2015-05-13 2016-05-10 Proceskontrolsystem til regulering og styring af et modulært opbygget anlæg til produktion af biofarmaceutiske og biologiske makromolekylære produkter DK3294856T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15167538.6A EP3093335A1 (de) 2015-05-13 2015-05-13 Prozessleitsystem zur regelung und steuerung einer modular aufgebauten anlage zur produktion von biopharmazeutischen und biologischen makromolekularen produkten
PCT/EP2016/060369 WO2016180798A1 (de) 2015-05-13 2016-05-10 Prozessleitsystem zur regelung und steuerung einer modular aufgebauten anlage zur produktion von biopharmazeutischen und biologischen makromolekularen produkten

Publications (1)

Publication Number Publication Date
DK3294856T3 true DK3294856T3 (da) 2019-12-09

Family

ID=53177195

Family Applications (1)

Application Number Title Priority Date Filing Date
DK16722163T DK3294856T3 (da) 2015-05-13 2016-05-10 Proceskontrolsystem til regulering og styring af et modulært opbygget anlæg til produktion af biofarmaceutiske og biologiske makromolekylære produkter

Country Status (21)

Country Link
US (2) US20180127461A1 (enExample)
EP (2) EP3093335A1 (enExample)
JP (1) JP6833721B2 (enExample)
KR (1) KR20180005225A (enExample)
CN (1) CN107849506B (enExample)
AR (1) AR104554A1 (enExample)
AU (1) AU2016259746B2 (enExample)
BR (1) BR112017024373B1 (enExample)
CA (1) CA2985678A1 (enExample)
DK (1) DK3294856T3 (enExample)
ES (1) ES2760468T3 (enExample)
IL (1) IL255556B (enExample)
MX (1) MX380681B (enExample)
PL (1) PL3294856T3 (enExample)
PT (1) PT3294856T (enExample)
RU (1) RU2724495C2 (enExample)
SA (1) SA517390330B1 (enExample)
SG (1) SG11201709329YA (enExample)
TW (1) TWI689303B (enExample)
WO (1) WO2016180798A1 (enExample)
ZA (1) ZA201708418B (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3431173A1 (en) 2017-07-19 2019-01-23 Bayer Pharma Aktiengesellschaft Continuous manufacture of guidance molecule drug conjugates
CN112639850A (zh) * 2018-09-05 2021-04-09 联邦科学和工业研究组织 用于多参数制造过程的监视器
EP3699697A1 (en) 2019-02-25 2020-08-26 Bayer Aktiengesellschaft Automated simultaneous process control
CN115698881A (zh) * 2020-05-29 2023-02-03 株式会社大赛璐 异常调制原因确定装置、异常调制原因确定方法以及异常调制原因确定程序
DE102022208467A1 (de) 2022-06-24 2024-01-04 Bilfinger Life Science Gmbh Modulare Vorrichtung und Verfahren zur kontinuierlichen Herstellung von biotechnologischen Produkten
WO2023247798A1 (de) 2022-06-24 2023-12-28 Bilfinger Life Science Gmbh Modulare vorrichtung und verfahren zur kontinuierlichen herstellung von biotechnologischen produkten

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994011838A1 (en) * 1992-11-06 1994-05-26 Abbott Laboratories Process control system for biological fluid testing
JP2004198123A (ja) * 2002-12-16 2004-07-15 Shimadzu Corp 分取液体クロマトグラフ質量分析装置
JP3823092B2 (ja) * 2003-03-11 2006-09-20 株式会社日立ハイテクノロジーズ 分離分析装置
JP2006018711A (ja) * 2004-07-05 2006-01-19 Earekkusu:Kk 液体除染剤供給システム
KR101238798B1 (ko) 2004-09-30 2013-03-04 바이엘 헬스케어, 엘엘씨 생물학적 분자의 통합된 연속 제조를 위한 장치 및 방법
EP1882030B1 (en) * 2005-05-09 2014-08-06 ALPHA PLAN GmbH Apparatus for providing media to cell culture modules
JP2009530615A (ja) * 2006-03-17 2009-08-27 ウオーターズ・インベストメンツ・リミテツド 流体完全性を維持し、グラジエントを予備成形する液体クロマトグラフィ用溶媒送液システム
JP4831480B2 (ja) * 2006-06-21 2011-12-07 三浦工業株式会社 膜濾過システム
CN103392124B (zh) * 2010-12-03 2016-04-20 塞普莱有限公司 细胞功能的微分析
JP2013544524A (ja) * 2010-12-06 2013-12-19 ターポン バイオシステムズ，インコーポレイテッド 生物学的生成物の連続プロセス法
CN103243026B (zh) * 2012-02-14 2014-09-03 常州医凌生命科技有限公司 多功能全自动细胞及溶液处理仪
EP2682168A1 (en) * 2012-07-02 2014-01-08 Millipore Corporation Purification of biological molecules
JP5930075B2 (ja) * 2013-01-18 2016-06-08 株式会社島津製作所 サンプル濃縮装置
HK1219964A1 (zh) 2013-03-08 2017-04-21 Genzyme Corporation 治疗性蛋白药物物质的整合连续制造
DE102013212540A1 (de) * 2013-06-27 2014-12-31 Agilent Technologies Inc. Konditionieren eines nachfolgenden Probenpakets in einer Probentrennstufe während Prozessierens eines vorangehenden Probenpakets in einer Probenweiterverarbeitungsstufe
EP3186355A4 (en) * 2014-07-31 2018-03-21 Govind Rao Microscale bioprocessing system and method for protein manufacturing from human blood

Also Published As

Publication number Publication date
EP3294856B1 (de) 2019-09-18
CN107849506A (zh) 2018-03-27
AU2016259746B2 (en) 2020-12-24
SA517390330B1 (ar) 2021-09-22
IL255556B (en) 2022-04-01
PL3294856T3 (pl) 2020-04-30
JP2018524668A (ja) 2018-08-30
RU2017143437A3 (enExample) 2019-08-29
US20180127461A1 (en) 2018-05-10
WO2016180798A1 (de) 2016-11-17
IL255556A (en) 2018-01-31
AU2016259746A8 (en) 2018-04-05
ZA201708418B (en) 2022-08-31
TW201717886A (zh) 2017-06-01
PT3294856T (pt) 2019-12-16
MX380681B (es) 2025-03-12
US20210221842A1 (en) 2021-07-22
BR112017024373A2 (pt) 2018-07-31
RU2017143437A (ru) 2019-06-13
CA2985678A1 (en) 2016-11-17
BR112017024373B1 (pt) 2022-08-09
JP6833721B2 (ja) 2021-02-24
RU2724495C2 (ru) 2020-06-23
KR20180005225A (ko) 2018-01-15
ES2760468T3 (es) 2020-05-14
SG11201709329YA (en) 2017-12-28
HK1252939A1 (zh) 2019-06-06
EP3294856A1 (de) 2018-03-21
CN107849506B (zh) 2020-11-03
AU2016259746A1 (en) 2017-12-07
AR104554A1 (es) 2017-07-26
TWI689303B (zh) 2020-04-01
EP3093335A1 (de) 2016-11-16
MX2017014527A (es) 2018-03-12

Similar Documents

Publication Publication Date Title
DK3294856T3 (da) Proceskontrolsystem til regulering og styring af et modulært opbygget anlæg til produktion af biofarmaceutiske og biologiske makromolekylære produkter
IL290749A (en) Assembly system for modular industrial plants
GB2601081B (en) Systems and methods for merging modular control systems into a process plant
DK3359348T3 (da) Robotsystem og fremgangsmåde til styring af et robotsystem
DK3291038T3 (da) Kontrol og overvågning af en proces til fremstilling af et kemisk, farmaceutisk eller bioteknologisk produkt
DK3131589T3 (da) Fremgangsmåde og anvendelse til fortløbende inaktivering af en virus under tilvejebringelse af et biologisk produkt
DK3400321T3 (da) System til produktion af dihydrogen og tilhørende fremgangsmåde
DK3247196T3 (da) Apparat og metode til plantning af plantestiklinger
EP3730254A4 (en) METHOD AND SYSTEM FOR CONTROLLING A MODULAR ROBOT
DK3369258T3 (da) System og fremgangsmåde til håndtering af en tilpasselig konfiguration i et høreapparat
DK3303659T3 (da) System til produktion af dihydrogen og tilhørende fremgangsmåde
DK3095296T3 (da) Fremgangsmåde og anordning til fremstilling af et produkt eller færdiggørelse af et produkt
DK3334693T3 (da) Kontinuerlig fremgangsmåde og system til behandlingen af spildevand
EP3355312A4 (en) INSTALLATION MAINTENANCE ASSISTANCE SYSTEM
DK3294549T3 (da) Et kompositprodukt og en fremgangsmåde til fremstilling af nævnte produkt
PT3359342T (pt) Sistema e método para controladores de fabrico modular autónomos
EP3260942A4 (en) Plant operation assistance system and plant operation assistance method
DK3331638T3 (da) System og fremgangsmåde til modtagelse af en engangsbeholder
EP3372929A4 (en) SHELVING SYSTEM AND CONTROL PROCESS THEREFOR
DK3481192T3 (da) Modulært blodproduktopbevaringssystem til temperatur-reguleret opbevaring af blodprodukter
DK3319667T3 (da) Sprøjte og fremgangsmåde til samling deraf
DK3562297T3 (da) System og metode til bestemmelse af planters status
DK3231788T3 (da) Fremgangsmåde til fremstilling af et muliefunktionelt produkt og indretning til anvendelse af nævnte fremgangsmåde
PL3494147T3 (pl) Sposób i układ sterowania instalacją do ciągłego wytwarzania polimeru
DK3078584T3 (da) Fremgangsmåde og system til ændring af et fartøjs fremdrift