DK3288946T3 - 5-ht2c-receptoragonister og sammensætninger og anvendelsesfremgangsmåder - Google Patents

5-ht2c-receptoragonister og sammensætninger og anvendelsesfremgangsmåder Download PDF

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Publication number
DK3288946T3
DK3288946T3 DK16721320T DK16721320T DK3288946T3 DK 3288946 T3 DK3288946 T3 DK 3288946T3 DK 16721320 T DK16721320 T DK 16721320T DK 16721320 T DK16721320 T DK 16721320T DK 3288946 T3 DK3288946 T3 DK 3288946T3
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DK
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Prior art keywords
compositions
methods
application
receptor agonists
ht2c receptor
Prior art date
Application number
DK16721320T
Other languages
English (en)
Inventor
Albert S Ren
Xiuwen Zhu
Carleton R Sage
Graeme Semple
Original Assignee
Arena Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Arena Pharm Inc filed Critical Arena Pharm Inc
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Publication of DK3288946T3 publication Critical patent/DK3288946T3/da

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/55131,4-Benzodiazepines, e.g. diazepam or clozapine
    • A61K31/55171,4-Benzodiazepines, e.g. diazepam or clozapine condensed with five-membered rings having nitrogen as a ring hetero atom, e.g. imidazobenzodiazepines, triazolam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/06Peri-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Child & Adolescent Psychology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK16721320T 2015-04-27 2016-04-26 5-ht2c-receptoragonister og sammensætninger og anvendelsesfremgangsmåder DK3288946T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562153082P 2015-04-27 2015-04-27
PCT/US2016/029308 WO2016176177A1 (en) 2015-04-27 2016-04-26 5-ht2c receptor agonists and compositions and methods of use

Publications (1)

Publication Number Publication Date
DK3288946T3 true DK3288946T3 (da) 2019-11-25

Family

ID=55949111

Family Applications (1)

Application Number Title Priority Date Filing Date
DK16721320T DK3288946T3 (da) 2015-04-27 2016-04-26 5-ht2c-receptoragonister og sammensætninger og anvendelsesfremgangsmåder

Country Status (18)

Country Link
US (1) US10392390B2 (da)
EP (1) EP3288946B1 (da)
JP (1) JP6675688B2 (da)
KR (1) KR102275505B1 (da)
CN (1) CN107873030B (da)
AU (1) AU2016255009B2 (da)
BR (1) BR112017023088B1 (da)
CA (1) CA3002544C (da)
DK (1) DK3288946T3 (da)
EA (1) EA034446B1 (da)
ES (1) ES2757922T3 (da)
HK (1) HK1244005B (da)
HR (1) HRP20192044T1 (da)
HU (1) HUE047169T2 (da)
IL (1) IL255171A0 (da)
MX (2) MX2017013902A (da)
PT (1) PT3288946T (da)
WO (1) WO2016176177A1 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2571696B (en) 2017-10-09 2020-05-27 Compass Pathways Ltd Large scale method for the preparation of Psilocybin and formulations of Psilocybin so produced
EP3733204A4 (en) 2017-12-27 2021-09-15 Takeda Pharmaceutical Company Limited THERAPEUTIC FOR EXERCISE INCONTINENCE AND STAIR INCONTINENCE
MX2020008086A (es) 2018-01-30 2021-02-15 Apnimed Inc Delaware Metodos y composiciones para tratar la apnea del sue?o.
WO2020163785A1 (en) * 2019-02-08 2020-08-13 The Brigham And Women's Hospital, Inc. Methods and compositions for treating sleep apnea
WO2020212948A1 (en) 2019-04-17 2020-10-22 Compass Pathfinder Limited Methods of treating neurocognitive disorders, chronic pain and reducing inflammation
WO2023076533A1 (en) * 2021-10-29 2023-05-04 Sensorium Therapeutics, Inc. Solid forms of mesembrine and therapeutic uses thereof
WO2023108165A2 (en) * 2021-12-10 2023-06-15 GATC Health Corp Methods of treating addiction and neurological disorders
WO2023172685A1 (en) 2022-03-10 2023-09-14 Arena Pharmaceuticals, Inc. Methods of treatment
WO2023225773A1 (en) * 2022-05-23 2023-11-30 Sensorium Therapeutics, Inc. Solid forms of mesembrine and therapeutic uses thereof

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4597961A (en) 1985-01-23 1986-07-01 Etscorn Frank T Transcutaneous application of nicotine
US4920989A (en) 1985-04-25 1990-05-01 Regents Of The University Of California Method and apparatus for aiding in the reduction of incidence of tobacco smoking
IL86170A (en) 1987-05-01 1992-12-01 Elan Transdermal Ltd Preparations and compositions comprising nicotine for percutaneous administration
US5004610A (en) 1988-06-14 1991-04-02 Alza Corporation Subsaturated nicotine transdermal therapeutic system
WO1992018005A1 (en) 1991-04-16 1992-10-29 National Institutes Of Health Method of treating trichotillomania and onychophagia
AU2002227170A1 (en) * 2000-11-03 2002-05-15 Wyeth Cycloalkyl(b)(1,4)diazepino(6,7,1-hi)indoles and derivatives
ES2230382T3 (es) * 2000-11-03 2005-05-01 Wyeth Ciclopental(b)(1,4)diazpino(6,7,1-hi)indoles como antagonistas de 5ht2c.
CA2482195A1 (en) 2002-04-12 2003-10-23 The University Of Chicago Farnesoid x-activated receptor agonists
EA016558B1 (ru) * 2003-06-17 2012-05-30 Арена Фармасьютикалз, Инк. Производные бензазепина, используемые для лечения заболеваний, ассоциированных с 5-ht-рецептором
WO2015066344A1 (en) * 2013-11-01 2015-05-07 Arena Pharmaceuticals, Inc. 5-ht2c receptor agonists and compositions and methods of use

Also Published As

Publication number Publication date
HRP20192044T1 (hr) 2020-02-07
IL255171A0 (en) 2017-12-31
AU2016255009B2 (en) 2020-10-08
NZ737412A (en) 2021-06-25
ES2757922T3 (es) 2020-04-30
MX2020005898A (es) 2020-08-13
CA3002544C (en) 2024-03-05
US10392390B2 (en) 2019-08-27
PT3288946T (pt) 2019-11-27
EP3288946A1 (en) 2018-03-07
CN107873030A (zh) 2018-04-03
JP6675688B2 (ja) 2020-04-01
BR112017023088B1 (pt) 2023-10-03
US20180186797A1 (en) 2018-07-05
WO2016176177A1 (en) 2016-11-03
KR102275505B1 (ko) 2021-07-08
AU2016255009A1 (en) 2017-12-14
KR20170140317A (ko) 2017-12-20
EA034446B1 (ru) 2020-02-10
JP2018519251A (ja) 2018-07-19
CN107873030B (zh) 2021-03-19
MX2017013902A (es) 2018-03-16
HK1244005B (zh) 2020-04-17
EA201792356A1 (ru) 2018-05-31
BR112017023088A2 (pt) 2018-07-10
HUE047169T2 (hu) 2020-04-28
CA3002544A1 (en) 2016-11-03
EP3288946B1 (en) 2019-08-21

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