DK3271357T3 - Fusionerede bicykliske heteroarylderivater med aktivitet som phd-inhibitorer - Google Patents
Fusionerede bicykliske heteroarylderivater med aktivitet som phd-inhibitorer Download PDFInfo
- Publication number
- DK3271357T3 DK3271357T3 DK16715122.4T DK16715122T DK3271357T3 DK 3271357 T3 DK3271357 T3 DK 3271357T3 DK 16715122 T DK16715122 T DK 16715122T DK 3271357 T3 DK3271357 T3 DK 3271357T3
- Authority
- DK
- Denmark
- Prior art keywords
- heteroeer
- bicycle
- merged
- derivatives
- phd inhibitors
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Epidemiology (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1504565.1A GB201504565D0 (en) | 2015-03-18 | 2015-03-18 | Novel compounds |
| PCT/JP2016/059782 WO2016148306A1 (en) | 2015-03-18 | 2016-03-17 | Fused bicyclic heteroaryl derivatives having activity as phd inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3271357T3 true DK3271357T3 (da) | 2020-02-17 |
Family
ID=53051992
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK16715122.4T DK3271357T3 (da) | 2015-03-18 | 2016-03-17 | Fusionerede bicykliske heteroarylderivater med aktivitet som phd-inhibitorer |
Country Status (32)
| Country | Link |
|---|---|
| US (1) | US10287286B2 (da) |
| EP (1) | EP3271357B1 (da) |
| JP (1) | JP6726681B2 (da) |
| KR (1) | KR102609431B1 (da) |
| CN (1) | CN107531698A (da) |
| AU (1) | AU2016234209B2 (da) |
| BR (1) | BR112017019653B1 (da) |
| CA (1) | CA2979024C (da) |
| CL (1) | CL2017002354A1 (da) |
| CO (1) | CO2017009353A2 (da) |
| CR (1) | CR20170468A (da) |
| DK (1) | DK3271357T3 (da) |
| DO (1) | DOP2017000209A (da) |
| EA (1) | EA035739B1 (da) |
| EC (1) | ECSP17069696A (da) |
| ES (1) | ES2774052T3 (da) |
| GB (1) | GB201504565D0 (da) |
| GE (1) | GEP20207095B (da) |
| HK (1) | HK1249512A1 (da) |
| HU (1) | HUE047918T2 (da) |
| IL (1) | IL254277B (da) |
| MX (1) | MX2017011902A (da) |
| MY (1) | MY194873A (da) |
| NZ (1) | NZ735631A (da) |
| PE (1) | PE20180656A1 (da) |
| PH (1) | PH12017501699A1 (da) |
| PT (1) | PT3271357T (da) |
| SG (1) | SG11201707280VA (da) |
| TN (1) | TN2017000384A1 (da) |
| UA (1) | UA123668C2 (da) |
| WO (1) | WO2016148306A1 (da) |
| ZA (1) | ZA201706612B (da) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK3419978T3 (da) | 2016-02-24 | 2020-06-02 | Pfizer | Pyrazolo[1,5-A]pyrazin-4-yl-derivater som JAK-hæmmere |
| WO2019034973A1 (en) | 2017-08-14 | 2019-02-21 | Pfizer Inc. | PYRAZOLO [1,5-A] PYRAZIN-4-YL AND RELATED DERIVATIVES |
| CA3106385A1 (en) * | 2018-09-13 | 2020-03-19 | Kissei Pharmaceutical Co., Ltd. | Imidazopyridinone compound |
| CN110950806A (zh) * | 2019-11-14 | 2020-04-03 | 安庆博曼生物技术有限公司 | 四乙基氯化铵催化嘧啶环羟基氯代制备方法 |
| JP7504822B2 (ja) | 2020-03-12 | 2024-06-24 | キッセイ薬品工業株式会社 | イミダゾピリジノン化合物を含む医薬組成物 |
| US11718622B2 (en) | 2020-03-16 | 2023-08-08 | Exelixis Inc. | Heterocyclic adenosine receptor antagonists |
| TW202233629A (zh) * | 2020-10-20 | 2022-09-01 | 美商安進公司 | 雜環螺環化合物及使用方法 |
| TW202334158A (zh) | 2021-10-28 | 2023-09-01 | 香港商英矽智能科技知識產權有限公司 | 含脯胺醯羥化酶結構域之蛋白質(phd)抑制劑及其用途 |
| WO2023111990A1 (en) * | 2021-12-17 | 2023-06-22 | Akebia Therapeutics, Inc. | Selective phd1 inhibitor compounds, compositions, and methods of use |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4209621A (en) | 1979-04-27 | 1980-06-24 | American Cyanamid Company | (Substituted-phenyl)-1,2,4-triazolo[4,3-a]-pyrimidines and (substituted-phenyl)-1,2,4-triazolo[1,5-a]pyrimidines |
| DK135184A (da) * | 1983-03-03 | 1984-10-10 | Riker Laboratories Inc | Triazol(4,3-c)- og triazol(1,5-c)pyrimidiner |
| US4572910A (en) * | 1983-03-03 | 1986-02-25 | Riker Laboratories, Inc. | Triazolo[1,5-c]pyrimidines substituted by nitrogen-containing heterocyclic rings |
| SK18412002A3 (sk) | 2000-06-30 | 2003-06-03 | Wyeth | Použitie substituovaných triazolopyrimidínových derivátov a farmaceutický prostriedok s ich obsahom |
| JP2010065026A (ja) | 2008-08-13 | 2010-03-25 | Ishihara Sangyo Kaisha Ltd | ピリジル−トリアゾロピリミジン誘導体又はその塩、並びにそれらを含有する有害生物防除剤 |
| JP2010065024A (ja) | 2008-08-14 | 2010-03-25 | Ishihara Sangyo Kaisha Ltd | トリアゾロピリミジン誘導体又はその塩を含有する有害生物防除剤 |
| US8283465B2 (en) * | 2009-07-17 | 2012-10-09 | Japan Tobacco Inc. | Triazolopyridine compound, and action thereof as prolyl hydroxylase inhibitor or erythropoietin production-inducing agent |
| JP2011168582A (ja) * | 2010-01-21 | 2011-09-01 | Ishihara Sangyo Kaisha Ltd | トリアゾロピリジン誘導体又はその塩、それらの製造方法及びそれらを含有する有害生物防除剤 |
| US20150239889A1 (en) | 2012-08-23 | 2015-08-27 | Mitsubishi Tanabe Pharma Corporation | Pyrazolopyrimidine compound |
-
2015
- 2015-03-18 GB GBGB1504565.1A patent/GB201504565D0/en not_active Ceased
-
2016
- 2016-03-17 GE GEAP201614608A patent/GEP20207095B/en unknown
- 2016-03-17 PT PT167151224T patent/PT3271357T/pt unknown
- 2016-03-17 NZ NZ735631A patent/NZ735631A/en unknown
- 2016-03-17 MX MX2017011902A patent/MX2017011902A/es active IP Right Grant
- 2016-03-17 BR BR112017019653-0A patent/BR112017019653B1/pt active IP Right Grant
- 2016-03-17 UA UAA201708877A patent/UA123668C2/uk unknown
- 2016-03-17 US US15/558,824 patent/US10287286B2/en active Active
- 2016-03-17 ES ES16715122T patent/ES2774052T3/es active Active
- 2016-03-17 PE PE2018000126A patent/PE20180656A1/es unknown
- 2016-03-17 MY MYPI2017703420A patent/MY194873A/en unknown
- 2016-03-17 CN CN201680022416.0A patent/CN107531698A/zh active Pending
- 2016-03-17 TN TNP/2017/000384A patent/TN2017000384A1/en unknown
- 2016-03-17 HU HUE16715122A patent/HUE047918T2/hu unknown
- 2016-03-17 EP EP16715122.4A patent/EP3271357B1/en active Active
- 2016-03-17 KR KR1020177030091A patent/KR102609431B1/ko active IP Right Grant
- 2016-03-17 CA CA2979024A patent/CA2979024C/en active Active
- 2016-03-17 JP JP2017549107A patent/JP6726681B2/ja active Active
- 2016-03-17 SG SG11201707280VA patent/SG11201707280VA/en unknown
- 2016-03-17 CR CR20170468A patent/CR20170468A/es unknown
- 2016-03-17 DK DK16715122.4T patent/DK3271357T3/da active
- 2016-03-17 WO PCT/JP2016/059782 patent/WO2016148306A1/en active Application Filing
- 2016-03-17 EA EA201792057A patent/EA035739B1/ru unknown
- 2016-03-17 AU AU2016234209A patent/AU2016234209B2/en active Active
-
2017
- 2017-09-03 IL IL254277A patent/IL254277B/en active IP Right Grant
- 2017-09-14 CO CONC2017/0009353A patent/CO2017009353A2/es unknown
- 2017-09-15 CL CL2017002354A patent/CL2017002354A1/es unknown
- 2017-09-15 PH PH12017501699A patent/PH12017501699A1/en unknown
- 2017-09-18 DO DO2017000209A patent/DOP2017000209A/es unknown
- 2017-10-02 ZA ZA2017/06612A patent/ZA201706612B/en unknown
- 2017-10-18 EC ECIEPI201769696A patent/ECSP17069696A/es unknown
-
2018
- 2018-07-13 HK HK18109089.3A patent/HK1249512A1/zh unknown
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