DK324182A - Fremgangsmaade til fremstilling af ergolinderivater - Google Patents

Fremgangsmaade til fremstilling af ergolinderivater Download PDF

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Publication number
DK324182A
DK324182A DK324182A DK324182A DK324182A DK 324182 A DK324182 A DK 324182A DK 324182 A DK324182 A DK 324182A DK 324182 A DK324182 A DK 324182A DK 324182 A DK324182 A DK 324182A
Authority
DK
Denmark
Prior art keywords
procedure
preparation
ergoline derivatives
ergoline
derivatives
Prior art date
Application number
DK324182A
Other languages
Danish (da)
English (en)
Inventor
L Bernardi
A Temperilli
G Bosisio
G Traquandi
A Rossi
P Salvati
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Publication of DK324182A publication Critical patent/DK324182A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
    • C07D457/06—Lysergic acid amides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK324182A 1981-07-21 1982-07-19 Fremgangsmaade til fremstilling af ergolinderivater DK324182A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8122356 1981-07-21
GB8209544 1982-03-31

Publications (1)

Publication Number Publication Date
DK324182A true DK324182A (da) 1983-01-22

Family

ID=26280189

Family Applications (1)

Application Number Title Priority Date Filing Date
DK324182A DK324182A (da) 1981-07-21 1982-07-19 Fremgangsmaade til fremstilling af ergolinderivater

Country Status (10)

Country Link
US (1) US4675404A (it)
EP (1) EP0070562B1 (it)
AU (1) AU553809B2 (it)
CA (1) CA1191840A (it)
CH (1) CH652407A5 (it)
DE (1) DE3264121D1 (it)
DK (1) DK324182A (it)
FI (1) FI76085C (it)
FR (1) FR2510115B1 (it)
IT (1) IT1210480B (it)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH653333A5 (de) * 1981-11-04 1985-12-31 Sandoz Ag N-substituierte ergolin- und 9,10-didehydroergolinderivate, ihre herstellung und sie enthaltende arzneimittel.
DE91652T1 (de) * 1982-04-13 1984-03-29 Farmitalia Carlo Erba S.p.A., 20159 Milano Ergolinderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen.
GB8515528D0 (en) * 1985-06-19 1985-07-24 Erba Farmitalia Ergoline derivatives
ATE204278T1 (de) * 1992-12-24 2001-09-15 Pharmacia & Upjohn Spa Serotoninergische ergolin derivate
GB9603226D0 (en) * 1996-02-15 1996-04-17 Pharmacia Spa Heterocyclyl-ergoline derivatives
AU2010601A (en) * 1999-12-16 2001-07-03 Novartis Ag Organic compounds
GB0409785D0 (en) * 2004-04-30 2004-06-09 Resolution Chemicals Ltd Preparation of cabergoline
GB0505965D0 (en) * 2005-03-23 2005-04-27 Resolution Chemicals Ltd Preparation of cabergoline
US7339060B2 (en) 2005-03-23 2008-03-04 Resolution Chemicals, Ltd. Preparation of cabergoline
US20070197576A1 (en) * 2006-02-08 2007-08-23 Resolution Chemicals Limited Production of Cabergoline and Novel Polymorphic Form Thereof
WO2011079313A1 (en) * 2009-12-23 2011-06-30 Map Pharmaceuticals, Inc. Novel ergoline analogs
KR20140042868A (ko) 2011-06-23 2014-04-07 맵 파마슈티컬스, 인코포레이티드 신규한 플루오로에르골린 유사체
EP2793580A4 (en) 2011-12-19 2015-05-20 Map Pharmaceuticals Inc NEW DERIVATIVES OF ISO-ERGOLINE
US8946420B2 (en) 2011-12-21 2015-02-03 Map Pharmaceuticals, Inc. Neuromodulatory compounds
US9012640B2 (en) 2012-06-22 2015-04-21 Map Pharmaceuticals, Inc. Cabergoline derivatives
US9657020B2 (en) 2015-01-20 2017-05-23 Xoc Pharmaceuticals, Inc. Ergoline compounds and uses thereof
BR112017015510A2 (pt) 2015-01-20 2018-01-30 Xoc Pharmaceuticals Inc composto de fórmula estrutural (i), método de tratamento e/ou prevenção, método de agonização do receptor d2 em um indivíduo, método de antagonização do receptor d3 em um indivíduo, método de agonização do receptor 5-ht1d em um indivíduo, método de agonização do receptor 5-ht1a em um indivíduo, método de agonização seletiva do receptor 5-ht1d em vez do receptor 5-ht1b em um indivíduo, método de agonização seletiva do re-ceptor 5-ht2c em vez do receptor 5-ht2a ou 5-ht2b em um indivíduo, método de agonização do receptor 5-ht2c em um indivíduo, método de fornecimento de atividade antagonista funcional no receptor 5-ht2b ou receptor 5-ht7, e, método de fornecimento de atividade antagonista funcional nos receptores adrenérgicos em um indivíduo
CA3064274A1 (en) 2017-06-01 2018-12-06 Xoc Pharmaceuticals, Inc. Ergoline derivatives for use in medicine

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA790063A (en) * 1968-07-16 Sandoz Patents Limited .delta.8,9-ergolene-8-carboxylic acid amide derivatives
US3238211A (en) * 1966-03-01 Derhvatives of g-methyl and i,g-dimethyl ergolhne
US3228939A (en) * 1966-01-11 Methyl and i,g-dimethyl-ergoline ii derivatives
CH347197A (de) * 1956-05-18 1960-06-30 Sandoz Ag Verfahren zur Herstellung von neuen am Indolstickstoff alkylierten Derivaten der Lysergsäure-Reihe
CH392532A (de) * 1960-10-07 1965-05-31 Sandoz Ag Verfahren zur Herstellung von heterocyclischen Amiden
US4035501A (en) * 1971-12-10 1977-07-12 Sandoz Ltd. N-lysergyl-amino-pyridines
FR2189046B1 (it) * 1972-06-22 1978-07-28 Farmaceutici Italia
US3920664A (en) * 1972-07-21 1975-11-18 Lilly Co Eli D-2-halo-6-alkyl-8-substituted ergolines and related compounds
US3880856A (en) * 1973-06-29 1975-04-29 Lilly Co Eli Ergoline dimers
HU172649B (hu) * 1975-04-24 1978-11-28 Gyogyszerkutato Intezet Sposob poluchenija novykh biologicheski aktivnykh lizergamidov
CS195905B1 (en) * 1976-12-06 1980-02-29 Milos Beran 6-substituted derivatives of d-8-ergolin-i-ylacetic acid amide and process for preparing thereof
GB1555751A (en) * 1977-02-02 1979-11-14 Farmaceutici Italia Ergoline deritatives
GB2056437A (en) * 1979-08-07 1981-03-18 Erba Farmitalia Secoergoline derivatives
NL8002812A (nl) * 1979-09-20 1981-03-24 Erba Farmitalia 6,7-secoergolinen.
GB2058746A (en) * 1979-09-20 1981-04-15 Erba Farmitalia 6,7-Secoergolines
US4526892A (en) * 1981-03-03 1985-07-02 Farmitalia Carlo Erba, S.P.A. Dimethylaminoalkyl-3-(ergoline-8'βcarbonyl)-ureas

Also Published As

Publication number Publication date
FI822528L (fi) 1983-01-22
FI76085C (fi) 1988-09-09
FI822528A0 (fi) 1982-07-16
CH652407A5 (it) 1985-11-15
AU553809B2 (en) 1986-07-31
FR2510115A1 (fr) 1983-01-28
IT1210480B (it) 1989-09-14
EP0070562B1 (en) 1985-06-12
IT8222459A0 (it) 1982-07-19
AU8610582A (en) 1983-01-27
DE3264121D1 (en) 1985-07-18
US4675404A (en) 1987-06-23
FR2510115B1 (fr) 1985-07-05
CA1191840A (en) 1985-08-13
FI76085B (fi) 1988-05-31
EP0070562A1 (en) 1983-01-26

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Legal Events

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AHB Application shelved due to non-payment