DK3207372T3 - Bestemmelse af bindingskonstanter ved ligevægtsforskydning - Google Patents

Bestemmelse af bindingskonstanter ved ligevægtsforskydning Download PDF

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Publication number
DK3207372T3
DK3207372T3 DK15780895.7T DK15780895T DK3207372T3 DK 3207372 T3 DK3207372 T3 DK 3207372T3 DK 15780895 T DK15780895 T DK 15780895T DK 3207372 T3 DK3207372 T3 DK 3207372T3
Authority
DK
Denmark
Prior art keywords
determination
equilibrium displacement
constants
bonding
bonding constants
Prior art date
Application number
DK15780895.7T
Other languages
English (en)
Inventor
Hinnerk Boriss
Original Assignee
3B Pharmaceuticals Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 3B Pharmaceuticals Gmbh filed Critical 3B Pharmaceuticals Gmbh
Application granted granted Critical
Publication of DK3207372T3 publication Critical patent/DK3207372T3/da

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306Solid-phase reaction mechanisms
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/92Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DK15780895.7T 2014-10-16 2015-10-15 Bestemmelse af bindingskonstanter ved ligevægtsforskydning DK3207372T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102014115088.0A DE102014115088A1 (de) 2014-10-16 2014-10-16 Bestimmung von Bindungskonstanten mittels Gleichgewichtsverlagerung
PCT/EP2015/073902 WO2016059164A1 (de) 2014-10-16 2015-10-15 Bestimmung von bindungskonstanten mittels gleichgewichtsverlagerung

Publications (1)

Publication Number Publication Date
DK3207372T3 true DK3207372T3 (da) 2019-05-06

Family

ID=54324995

Family Applications (1)

Application Number Title Priority Date Filing Date
DK15780895.7T DK3207372T3 (da) 2014-10-16 2015-10-15 Bestemmelse af bindingskonstanter ved ligevægtsforskydning

Country Status (9)

Country Link
US (1) US10634663B2 (da)
EP (1) EP3207372B1 (da)
JP (1) JP6557816B2 (da)
CN (1) CN107110856B (da)
CA (1) CA2964429C (da)
DE (1) DE102014115088A1 (da)
DK (1) DK3207372T3 (da)
ES (1) ES2728118T3 (da)
WO (1) WO2016059164A1 (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102014115088A1 (de) 2014-10-16 2016-04-21 Sovicell Gmbh Bestimmung von Bindungskonstanten mittels Gleichgewichtsverlagerung
EP4122499A1 (en) 2021-07-23 2023-01-25 3B Pharmaceuticals GmbH Fibroblast activation protein inhibitors and use thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0203548D0 (sv) 2002-12-02 2002-12-02 Biacore Ab Method of determining site-specificity and kit therefor
DE602004009318T2 (de) 2003-08-16 2008-07-10 Bayer Healthcare Ag Bestimmung freier fraktionen
DE10350525A1 (de) 2003-10-29 2005-06-09 Bayer Technology Services Gmbh Verfahren zur Visualisierung der ADME-Eigenschaften chemischer Substanzen
SE0401633D0 (sv) 2004-06-24 2004-06-24 Biacore Ab Method for detecting molecular surface interactions
DE102010018965A1 (de) 2010-04-27 2011-10-27 Sovicell Gmbh Bestimmung von Wechselwirkungen zwischen einer Substanz oder einem Substanzgemisch und einem Target
DE102014115088A1 (de) 2014-10-16 2016-04-21 Sovicell Gmbh Bestimmung von Bindungskonstanten mittels Gleichgewichtsverlagerung

Also Published As

Publication number Publication date
US20170227524A1 (en) 2017-08-10
EP3207372A1 (de) 2017-08-23
EP3207372B1 (de) 2019-01-23
CA2964429C (en) 2021-02-16
DE102014115088A1 (de) 2016-04-21
WO2016059164A1 (de) 2016-04-21
US10634663B2 (en) 2020-04-28
ES2728118T3 (es) 2019-10-22
JP2017534867A (ja) 2017-11-24
CA2964429A1 (en) 2016-04-21
CN107110856A (zh) 2017-08-29
JP6557816B2 (ja) 2019-08-14
CN107110856B (zh) 2020-06-30

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