DK319277A - Hydroxysuccinimidestere fremgangsmade til fremstilling heraf og anvendelse heraf - Google Patents

Hydroxysuccinimidestere fremgangsmade til fremstilling heraf og anvendelse heraf

Info

Publication number
DK319277A
DK319277A DK319277A DK319277A DK319277A DK 319277 A DK319277 A DK 319277A DK 319277 A DK319277 A DK 319277A DK 319277 A DK319277 A DK 319277A DK 319277 A DK319277 A DK 319277A
Authority
DK
Denmark
Prior art keywords
hydroxysuccinimidester
manufacture
methods
hydroxysuccinimidester methods
Prior art date
Application number
DK319277A
Other languages
English (en)
Inventor
H G Batz
J Horn
K Stellner
J Maier
M Nelboeck
G Weimann
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of DK319277A publication Critical patent/DK319277A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F20/00—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride, ester, amide, imide or nitrile thereof
    • C08F20/02—Monocarboxylic acids having less than ten carbon atoms, Derivatives thereof
    • C08F20/10—Esters
    • C08F20/34—Esters containing nitrogen, e.g. N,N-dimethylaminoethyl (meth)acrylate
    • C08F20/36—Esters containing nitrogen, e.g. N,N-dimethylaminoethyl (meth)acrylate containing oxygen in addition to the carboxy oxygen, e.g. 2-N-morpholinoethyl (meth)acrylate or 2-isocyanatoethyl (meth)acrylate
DK319277A 1976-07-14 1977-07-13 Hydroxysuccinimidestere fremgangsmade til fremstilling heraf og anvendelse heraf DK319277A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2631656A DE2631656C2 (de) 1976-07-14 1976-07-14 Verwendung eines Hydroxysuccinimidoester-Derivats zur Bindung von biologisch aktiven Proteinen aneinander und/oder an flüssige oder feste Trägerstoffe

Publications (1)

Publication Number Publication Date
DK319277A true DK319277A (da) 1978-01-15

Family

ID=5983006

Family Applications (1)

Application Number Title Priority Date Filing Date
DK319277A DK319277A (da) 1976-07-14 1977-07-13 Hydroxysuccinimidestere fremgangsmade til fremstilling heraf og anvendelse heraf

Country Status (11)

Country Link
US (2) US4155914A (da)
JP (1) JPS6014028B2 (da)
AT (1) AT360981B (da)
DE (1) DE2631656C2 (da)
DK (1) DK319277A (da)
FR (1) FR2358394A1 (da)
GB (1) GB1523711A (da)
HU (1) HU175883B (da)
IT (1) IT1080882B (da)
NL (1) NL168220C (da)
SE (1) SE424319B (da)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55145665A (en) * 1979-05-02 1980-11-13 Haruo Ogura Agent for forming active ester of amino acid
US4487715A (en) * 1982-07-09 1984-12-11 The Regents Of The University Of California Method of conjugating oligopeptides
JPS6169759A (ja) * 1984-09-14 1986-04-10 Agency Of Ind Science & Technol タンパク質の架橋反応用修飾剤及びそれを用いる方法
FR2574075B1 (fr) * 1984-12-04 1987-09-18 Poudres & Explosifs Ste Nale Procede de synthese d'esters actifs d'acides carboxyliques, nouveaux carbonates alpha-halogenes utiles pour cette synthese et leur mode d'obtention
US4643991A (en) * 1984-12-18 1987-02-17 The University Of Kentucky Research Foundation Peptide elastase inhibitors and methods
JPH0527613Y2 (da) * 1988-04-25 1993-07-14
HUT64022A (en) * 1989-04-19 1993-11-29 Enzon Inc Process for producing active polyalkileneoxide carbonates for the modification of polypeptides
US5122614A (en) * 1989-04-19 1992-06-16 Enzon, Inc. Active carbonates of polyalkylene oxides for modification of polypeptides
US5324844A (en) * 1989-04-19 1994-06-28 Enzon, Inc. Active carbonates of polyalkylene oxides for modification of polypeptides
DE3924705A1 (de) * 1989-07-26 1991-01-31 Boehringer Mannheim Gmbh Heterobifunktionelle verbindungen
US5672662A (en) * 1995-07-07 1997-09-30 Shearwater Polymers, Inc. Poly(ethylene glycol) and related polymers monosubstituted with propionic or butanoic acids and functional derivatives thereof for biotechnical applications
US6284246B1 (en) 1997-07-30 2001-09-04 The Procter & Gamble Co. Modified polypeptides with high activity and reduced allergenicity
US6495136B1 (en) 1998-03-26 2002-12-17 The Procter & Gamble Company Proteases having modified amino acid sequences conjugated to addition moieties
CN1301305A (zh) 1998-03-26 2001-06-27 宝洁公司 具有氨基酸取代的丝氨酸蛋白酶变体
US6908757B1 (en) 1998-03-26 2005-06-21 The Procter & Gamble Company Serine protease variants having amino acid deletions and substitutions
CZ2002212A3 (cs) 1999-07-22 2002-07-17 The Procter & Gamble Company Varianty subtilisinové proteasy mající aminokyselinové substituce v definovaných epitopových oblastech
US6946128B1 (en) 1999-07-22 2005-09-20 The Procter & Gamble Company Protease conjugates having sterically protected epitope regions
CZ2002220A3 (cs) 1999-07-22 2002-05-15 The Procter & Gamble Company Varianty subtilisinové proteasy s delecemi a substitucemi aminokyselin v definovaných epitopových regionech
MXPA02000842A (es) 1999-07-22 2002-07-30 Procter & Gamble Conjugados de proteasa que tienen sitios de corte protegidos estericamente.
WO2001018080A1 (en) * 1999-09-08 2001-03-15 School Of Pharmacy, University Of London Uniform molecular weight polymers
ES2315526T3 (es) 2002-09-09 2009-04-01 Nektar Therapeutics Al, Corporation Metodo para preparar derivados polimericos solubles en agua que llevan un acido carboxilico terminal.
US7361767B2 (en) * 2003-11-14 2008-04-22 3M Innovative Properties Company N-sulfonyldicarboximide containing tethering compounds
US7423155B2 (en) * 2003-11-14 2008-09-09 3M Innovative Properties Company N-sulfonyldicarboximide containing tethering compounds
JP5015608B2 (ja) * 2004-01-21 2012-08-29 ネクター セラピューティクス プロピオン酸末端ポリマーの調製方法
WO2007022780A1 (en) * 2005-08-26 2007-03-01 Novo Nordisk A/S A method of modifying a macromolecular system
US7544756B2 (en) * 2005-09-30 2009-06-09 3M Innovative Properties Company Crosslinked polymers with amine binding groups
US7544755B2 (en) * 2005-09-30 2009-06-09 3M Innovative Properties Company Crosslinked polymers with amine binding groups
EP2271602A4 (en) 2008-04-01 2013-03-06 Univ Georgia State Res Found SURFACE-ACTIVE MONOLITHIC COLUMNS, METHODS OF MAKING SAME, AND METHODS OF USE THEREOF

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2260185C3 (de) * 1971-06-09 1979-06-13 Boehringer Mannheim Gmbh, 6800 Mannheim Trägergebundenes Protein und Verfahren zu seiner Herstellung
US3978079A (en) * 1972-02-04 1976-08-31 American Cyanamid Company Chemiluminescence
DE2346937A1 (de) * 1973-09-18 1975-04-03 Bayer Ag N'-(aminoacylaminophenyl)-acetamidine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
US3940420A (en) * 1974-07-15 1976-02-24 Pierce Chemical Company Compound, dithiobis-(succinimidyl propionate)
US3996268A (en) * 1974-09-03 1976-12-07 The Regents Of The University Of California Cross-linking reagent for insulin synthesis

Also Published As

Publication number Publication date
SE424319B (sv) 1982-07-12
US4248786A (en) 1981-02-03
JPS6014028B2 (ja) 1985-04-11
ATA376577A (de) 1980-07-15
DE2631656A1 (de) 1978-01-19
JPS539762A (en) 1978-01-28
NL168220C (nl) 1982-03-16
NL168220B (nl) 1981-10-16
FR2358394B1 (da) 1980-02-15
DE2631656C2 (de) 1983-02-10
SE7707734L (sv) 1978-01-15
IT1080882B (it) 1985-05-16
GB1523711A (en) 1978-09-06
NL7706944A (nl) 1978-01-17
US4155914A (en) 1979-05-22
FR2358394A1 (fr) 1978-02-10
HU175883B (en) 1980-11-28
AT360981B (de) 1981-02-10

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment