DK3189839T3 - N-piperidinylacetamidderivater som calciumkanalblokkere - Google Patents

N-piperidinylacetamidderivater som calciumkanalblokkere Download PDF

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Publication number
DK3189839T3
DK3189839T3 DK17155716.8T DK17155716T DK3189839T3 DK 3189839 T3 DK3189839 T3 DK 3189839T3 DK 17155716 T DK17155716 T DK 17155716T DK 3189839 T3 DK3189839 T3 DK 3189839T3
Authority
DK
Denmark
Prior art keywords
piperidinylacetamide
derivatives
calcium channel
channel blockers
blockers
Prior art date
Application number
DK17155716.8T
Other languages
Danish (da)
English (en)
Inventor
Hassan Pajouhesh
Ramesh Kaul
Yanbing Ding
Yongbao Zhu
Lingyun Zhang
Nagasree Chakka
Mike Grimwood
Jason Tan
Yuanxi Zhou
Original Assignee
Praxis Prec Medicines Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US12/420,793 external-priority patent/US8377968B2/en
Application filed by Praxis Prec Medicines Inc filed Critical Praxis Prec Medicines Inc
Application granted granted Critical
Publication of DK3189839T3 publication Critical patent/DK3189839T3/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/26Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK17155716.8T 2008-06-02 2009-06-02 N-piperidinylacetamidderivater som calciumkanalblokkere DK3189839T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5817908P 2008-06-02 2008-06-02
US12/420,793 US8377968B2 (en) 2008-06-02 2009-04-08 N-piperidinyl acetamide derivatives as calcium channel blockers
EP09757002.2A EP2300007B1 (en) 2008-06-02 2009-06-02 N-piperidinyl acetamide derivatives as calcium channel blockers

Publications (1)

Publication Number Publication Date
DK3189839T3 true DK3189839T3 (da) 2020-08-17

Family

ID=66624650

Family Applications (1)

Application Number Title Priority Date Filing Date
DK17155716.8T DK3189839T3 (da) 2008-06-02 2009-06-02 N-piperidinylacetamidderivater som calciumkanalblokkere

Country Status (7)

Country Link
DK (1) DK3189839T3 (es)
ES (1) ES2812244T3 (es)
HU (1) HUE051677T2 (es)
IL (1) IL262216B (es)
LT (1) LT3189839T (es)
PT (1) PT3189839T (es)
SI (1) SI3189839T1 (es)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1896414A4 (en) * 2005-06-23 2009-09-09 Merck & Co Inc 3-FLUOR-PIPERIDINE T-TYPE CALCIUM CHANNEL ANTAGONISTS
CA2611639A1 (en) * 2005-06-29 2007-01-04 Merck & Co., Inc. 4-fluoro-piperidine t-type calcium channel antagonists

Also Published As

Publication number Publication date
LT3189839T (lt) 2020-11-10
IL262216A (en) 2018-11-29
IL262216B (en) 2022-02-01
ES2812244T3 (es) 2021-03-16
PT3189839T (pt) 2020-08-28
SI3189839T1 (sl) 2021-04-30
HUE051677T2 (hu) 2021-03-29

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