SI3189839T1 - Derivati N-piperidinil acetamida kot blokatorji kalcijevih kanalčkov - Google Patents

Derivati N-piperidinil acetamida kot blokatorji kalcijevih kanalčkov

Info

Publication number
SI3189839T1
SI3189839T1 SI200932084T SI200932084T SI3189839T1 SI 3189839 T1 SI3189839 T1 SI 3189839T1 SI 200932084 T SI200932084 T SI 200932084T SI 200932084 T SI200932084 T SI 200932084T SI 3189839 T1 SI3189839 T1 SI 3189839T1
Authority
SI
Slovenia
Prior art keywords
calcium channel
channel blockers
acetamide derivatives
piperidinyl acetamide
piperidinyl
Prior art date
Application number
SI200932084T
Other languages
English (en)
Slovenian (sl)
Inventor
Hassan Pajouhesh
Ramesh Kaul
Yanbing Ding
Yongbao Zhu
Lingyun Zhang
Nagasree Chakka
Mike Grimwood
Jason Tan
Yuanxi Zhou
Original Assignee
Praxis Precision Medicines, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US12/420,793 external-priority patent/US8377968B2/en
Application filed by Praxis Precision Medicines, Inc. filed Critical Praxis Precision Medicines, Inc.
Publication of SI3189839T1 publication Critical patent/SI3189839T1/sl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/26Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
SI200932084T 2008-06-02 2009-06-02 Derivati N-piperidinil acetamida kot blokatorji kalcijevih kanalčkov SI3189839T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5817908P 2008-06-02 2008-06-02
US12/420,793 US8377968B2 (en) 2008-06-02 2009-04-08 N-piperidinyl acetamide derivatives as calcium channel blockers
EP17155716.8A EP3189839B1 (en) 2008-06-02 2009-06-02 N-piperidinyl acetamide derivatives as calcium channel blockers

Publications (1)

Publication Number Publication Date
SI3189839T1 true SI3189839T1 (sl) 2021-04-30

Family

ID=66624650

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200932084T SI3189839T1 (sl) 2008-06-02 2009-06-02 Derivati N-piperidinil acetamida kot blokatorji kalcijevih kanalčkov

Country Status (7)

Country Link
DK (1) DK3189839T3 (es)
ES (1) ES2812244T3 (es)
HU (1) HUE051677T2 (es)
IL (1) IL262216B (es)
LT (1) LT3189839T (es)
PT (1) PT3189839T (es)
SI (1) SI3189839T1 (es)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100222387A1 (en) * 2005-06-23 2010-09-02 Barrow James C 3-Fluoro-Piperidine T-Type Calcium Channel Antagonists
EP1901746B1 (en) * 2005-06-29 2013-02-20 Merck Sharp & Dohme Corp. 4-fluoro-piperidine t-type calcium channel antagonists

Also Published As

Publication number Publication date
HUE051677T2 (hu) 2021-03-29
ES2812244T3 (es) 2021-03-16
DK3189839T3 (da) 2020-08-17
PT3189839T (pt) 2020-08-28
IL262216B (en) 2022-02-01
IL262216A (en) 2018-11-29
LT3189839T (lt) 2020-11-10

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