LT3189839T - N-piperidinil acetamido dariniai kaip kalcio kanalų blokatoriai - Google Patents

N-piperidinil acetamido dariniai kaip kalcio kanalų blokatoriai

Info

Publication number
LT3189839T
LT3189839T LTEP17155716.8T LT17155716T LT3189839T LT 3189839 T LT3189839 T LT 3189839T LT 17155716 T LT17155716 T LT 17155716T LT 3189839 T LT3189839 T LT 3189839T
Authority
LT
Lithuania
Prior art keywords
calcium channel
channel blockers
acetamide derivatives
piperidinyl acetamide
piperidinyl
Prior art date
Application number
LTEP17155716.8T
Other languages
English (en)
Lithuanian (lt)
Inventor
Hassan Pajouhesh
Ramesh Kaul
Yanbing Ding
Yongbao Zhu
Lingyun Zhang
Nagasree Chakka
Mike Grimwood
Jason Tan
Yuanxi Zhou
Original Assignee
Praxis Precision Medicines, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US12/420,793 external-priority patent/US8377968B2/en
Application filed by Praxis Precision Medicines, Inc. filed Critical Praxis Precision Medicines, Inc.
Publication of LT3189839T publication Critical patent/LT3189839T/lt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
LTEP17155716.8T 2008-06-02 2009-06-02 N-piperidinil acetamido dariniai kaip kalcio kanalų blokatoriai LT3189839T (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5817908P 2008-06-02 2008-06-02
US12/420,793 US8377968B2 (en) 2008-06-02 2009-04-08 N-piperidinyl acetamide derivatives as calcium channel blockers

Publications (1)

Publication Number Publication Date
LT3189839T true LT3189839T (lt) 2020-11-10

Family

ID=66624650

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEP17155716.8T LT3189839T (lt) 2008-06-02 2009-06-02 N-piperidinil acetamido dariniai kaip kalcio kanalų blokatoriai

Country Status (7)

Country Link
DK (1) DK3189839T3 (es)
ES (1) ES2812244T3 (es)
HU (1) HUE051677T2 (es)
IL (1) IL262216B (es)
LT (1) LT3189839T (es)
PT (1) PT3189839T (es)
SI (1) SI3189839T1 (es)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100222387A1 (en) * 2005-06-23 2010-09-02 Barrow James C 3-Fluoro-Piperidine T-Type Calcium Channel Antagonists
EP1901746B1 (en) * 2005-06-29 2013-02-20 Merck Sharp & Dohme Corp. 4-fluoro-piperidine t-type calcium channel antagonists

Also Published As

Publication number Publication date
HUE051677T2 (hu) 2021-03-29
ES2812244T3 (es) 2021-03-16
DK3189839T3 (da) 2020-08-17
PT3189839T (pt) 2020-08-28
IL262216B (en) 2022-02-01
IL262216A (en) 2018-11-29
SI3189839T1 (sl) 2021-04-30

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