PT3189839T - Derivados de acetamida n-piperidinilo como bloqueadores de canais de cálcio - Google Patents

Derivados de acetamida n-piperidinilo como bloqueadores de canais de cálcio

Info

Publication number
PT3189839T
PT3189839T PT171557168T PT17155716T PT3189839T PT 3189839 T PT3189839 T PT 3189839T PT 171557168 T PT171557168 T PT 171557168T PT 17155716 T PT17155716 T PT 17155716T PT 3189839 T PT3189839 T PT 3189839T
Authority
PT
Portugal
Prior art keywords
calcium channel
channel blockers
acetamide derivatives
piperidinyl acetamide
piperidinyl
Prior art date
Application number
PT171557168T
Other languages
English (en)
Original Assignee
Praxis Prec Medicines Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US12/420,793 external-priority patent/US8377968B2/en
Application filed by Praxis Prec Medicines Inc filed Critical Praxis Prec Medicines Inc
Publication of PT3189839T publication Critical patent/PT3189839T/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/26Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT171557168T 2008-06-02 2009-06-02 Derivados de acetamida n-piperidinilo como bloqueadores de canais de cálcio PT3189839T (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5817908P 2008-06-02 2008-06-02
US12/420,793 US8377968B2 (en) 2008-06-02 2009-04-08 N-piperidinyl acetamide derivatives as calcium channel blockers

Publications (1)

Publication Number Publication Date
PT3189839T true PT3189839T (pt) 2020-08-28

Family

ID=66624650

Family Applications (1)

Application Number Title Priority Date Filing Date
PT171557168T PT3189839T (pt) 2008-06-02 2009-06-02 Derivados de acetamida n-piperidinilo como bloqueadores de canais de cálcio

Country Status (7)

Country Link
DK (1) DK3189839T3 (pt)
ES (1) ES2812244T3 (pt)
HU (1) HUE051677T2 (pt)
IL (1) IL262216B (pt)
LT (1) LT3189839T (pt)
PT (1) PT3189839T (pt)
SI (1) SI3189839T1 (pt)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100222387A1 (en) * 2005-06-23 2010-09-02 Barrow James C 3-Fluoro-Piperidine T-Type Calcium Channel Antagonists
WO2007002884A2 (en) * 2005-06-29 2007-01-04 Merck & Co., Inc. 4-fluoro-piperidine t-type calcium channel antagonists

Also Published As

Publication number Publication date
LT3189839T (lt) 2020-11-10
DK3189839T3 (da) 2020-08-17
SI3189839T1 (sl) 2021-04-30
ES2812244T3 (es) 2021-03-16
HUE051677T2 (hu) 2021-03-29
IL262216A (en) 2018-11-29
IL262216B (en) 2022-02-01

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