DK3183337T3 - Use of Jagged 1 / Frizzled 4 as cell surface marker for isolation of human cardiac ventricular progenitor cells - Google Patents

Use of Jagged 1 / Frizzled 4 as cell surface marker for isolation of human cardiac ventricular progenitor cells Download PDF

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Publication number
DK3183337T3
DK3183337T3 DK15759585.1T DK15759585T DK3183337T3 DK 3183337 T3 DK3183337 T3 DK 3183337T3 DK 15759585 T DK15759585 T DK 15759585T DK 3183337 T3 DK3183337 T3 DK 3183337T3
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cells
human
cardiac
jagged
cell
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DK15759585.1T
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Kenneth R Chien
Xiaojun Lian
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Procella Therapeutics Ab
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0657Cardiomyocytes; Heart cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/34Muscles; Smooth muscle cells; Heart; Cardiac stem cells; Myoblasts; Myocytes; Cardiomyocytes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/40Regulators of development
    • C12N2501/415Wnt; Frizzeled
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    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/40Regulators of development
    • C12N2501/42Notch; Delta; Jagged; Serrate
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2503/00Use of cells in diagnostics
    • C12N2503/02Drug screening
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    • C12N2506/00Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
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    • C12N2506/00Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
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    • C12N2506/00Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
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DK15759585.1T 2014-08-22 2015-08-21 Use of Jagged 1 / Frizzled 4 as cell surface marker for isolation of human cardiac ventricular progenitor cells DK3183337T3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462040892P 2014-08-22 2014-08-22
US201562194016P 2015-07-17 2015-07-17
PCT/US2015/046309 WO2016029122A1 (en) 2014-08-22 2015-08-21 Use of jagged 1/frizzled 4 as a cell surface marker for isolating human cardiac ventricular progenitor cells

Publications (1)

Publication Number Publication Date
DK3183337T3 true DK3183337T3 (en) 2019-04-01

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DK15759585.1T DK3183337T3 (en) 2014-08-22 2015-08-21 Use of Jagged 1 / Frizzled 4 as cell surface marker for isolation of human cardiac ventricular progenitor cells

Country Status (6)

Country Link
US (1) US10597637B2 (enExample)
EP (2) EP3183337B1 (enExample)
JP (2) JP6738808B2 (enExample)
DK (1) DK3183337T3 (enExample)
MA (1) MA40589A (enExample)
WO (1) WO2016029122A1 (enExample)

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US10596200B2 (en) 2014-08-22 2020-03-24 Procella Therapeutics Ab Use of LIFR or FGFR3 as a cell surface marker for isolating human cardiac ventricular progenitor cells
DK3183337T3 (en) 2014-08-22 2019-04-01 Procella Therapeutics Ab Use of Jagged 1 / Frizzled 4 as cell surface marker for isolation of human cardiac ventricular progenitor cells
WO2017172086A1 (en) * 2016-02-19 2017-10-05 Leung Chuen Yan Genetic markers for engraftment of human cardiac ventricular progenitor cells
WO2017192606A1 (en) * 2016-05-02 2017-11-09 Emory University Methods of producing specialized cardio-like cells from stem cell
US11352604B2 (en) * 2016-09-30 2022-06-07 Wisconsin Alumni Research Foundation Method of making cardiomyocytes from human pluripotent cells
US10508263B2 (en) * 2016-11-29 2019-12-17 Procella Therapeutics Ab Methods for isolating human cardiac ventricular progenitor cells
US10767164B2 (en) 2017-03-30 2020-09-08 The Research Foundation For The State University Of New York Microenvironments for self-assembly of islet organoids from stem cells differentiation
WO2019038587A1 (en) 2017-08-23 2019-02-28 Procella Therapeutics Ab USE OF NEUROPILIN-1 (NRP1) AS A CELL SURFACE MARKER FOR ISOLATING HUMAN CARDIAC VENTRICULAR PROGENITOR CELLS
CN109189051A (zh) * 2018-10-29 2019-01-11 江苏罗思韦尔电气有限公司 一种基于T-Box的故障存储及处理方法
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US20230330264A1 (en) 2022-04-15 2023-10-19 Smartcella Solutions Ab COMPOSITIONS AND METHODS FOR EXOSOME-MEDIATED DELIVERY OF mRNA AGENTS
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US10508263B2 (en) 2016-11-29 2019-12-17 Procella Therapeutics Ab Methods for isolating human cardiac ventricular progenitor cells

Also Published As

Publication number Publication date
JP2020120677A (ja) 2020-08-13
EP3183337A1 (en) 2017-06-28
MA40589A (fr) 2017-06-28
EP3183337B1 (en) 2019-02-06
US10597637B2 (en) 2020-03-24
JP6738808B2 (ja) 2020-08-12
US20160053229A1 (en) 2016-02-25
WO2016029122A1 (en) 2016-02-25
EP3524673A1 (en) 2019-08-14
JP2017525393A (ja) 2017-09-07

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