DK3134526T3 - LNC RNAs for therapy and diagnosis of cardiac hypertrophy - Google Patents
LNC RNAs for therapy and diagnosis of cardiac hypertrophy Download PDFInfo
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- DK3134526T3 DK3134526T3 DK15717502.7T DK15717502T DK3134526T3 DK 3134526 T3 DK3134526 T3 DK 3134526T3 DK 15717502 T DK15717502 T DK 15717502T DK 3134526 T3 DK3134526 T3 DK 3134526T3
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- A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
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- C12N2320/30—Special therapeutic applications
- C12N2320/32—Special delivery means, e.g. tissue-specific
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
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| EP14165504 | 2014-04-22 | ||
| PCT/EP2015/058684 WO2015162161A1 (en) | 2014-04-22 | 2015-04-22 | Lncrnas for therapy and diagnosis of cardiac hypertrophy |
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| GB201608907D0 (en) * | 2016-05-20 | 2016-07-06 | Ucl Business Plc | Means for modulating gene expression |
| WO2018229046A1 (en) * | 2017-06-12 | 2018-12-20 | Firalis Sa | DIAGNOSTIC, PROGNOSTIC AND THERAPEUTIC USES OF LONG NONCODING RNAs FOR PATHOLOGIES AND TOXICITIES INDUCING HEART DISORDERS |
| CN111032093A (zh) * | 2017-06-19 | 2020-04-17 | 洛桑大学 | 控制心肌纤维化和重塑的方法和组合物 |
| CN107326072A (zh) * | 2017-06-23 | 2017-11-07 | 陈梦麟 | Linc00702及其在调控心血管系统中的应用 |
| WO2019014656A1 (en) | 2017-07-14 | 2019-01-17 | Han Si Ping | METALLIC OLIGONUCLEOTIDE JONCTIONS FOR THE ADMINISTRATION OF THERAPEUTIC AGENTS |
| WO2019033079A1 (en) * | 2017-08-10 | 2019-02-14 | City Of Hope | CONDITIONAL RNAIDS AND THEIR USES IN THE TREATMENT OF CARDIAC HYPERTROPHY |
| CN113166750B (zh) | 2018-08-10 | 2025-02-18 | 希望之城 | 可编程的条件性sirna及其用途 |
| KR20210148232A (ko) | 2019-04-01 | 2021-12-07 | 테나야 테라퓨틱스, 인코포레이티드 | 조작된 캡시드를 갖는 아데노-연관 바이러스 |
| CN110229879B (zh) * | 2019-07-01 | 2022-11-18 | 青岛大学 | 一种piRNA-500核苷酸类似物及其反义核苷酸的应用和应用其的产品 |
| CN110878348B (zh) * | 2019-11-19 | 2023-03-28 | 南京启医科技有限公司 | 一种具有较高特异性的心衰lnc RNA生物标志物及其检测方法和应用 |
| CN111690673A (zh) * | 2020-06-22 | 2020-09-22 | 扬州大学 | 一种lncRNA通过编码小肽促进PGCs形成的验证方法 |
| CN112494651A (zh) * | 2020-09-30 | 2021-03-16 | 吉林大学 | lncRNA H19作为分子靶点在动脉粥样硬化治疗中的应用 |
| US11781156B2 (en) | 2020-10-09 | 2023-10-10 | Tenaya Therapeutics, Inc. | Plakophillin-2 gene therapy methods and compositions |
| MX2023003984A (es) * | 2020-10-09 | 2023-04-24 | Tenaya Therapeutics Inc | Metodos y composiciones para terapia genica con placofilina-2. |
| CN114959008B (zh) * | 2022-04-20 | 2024-11-26 | 华中科技大学同济医学院附属协和医院 | 长链非编码RNA-lnc-TSI的用途 |
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| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| US6080560A (en) | 1994-07-25 | 2000-06-27 | Monsanto Company | Method for producing antibodies in plant cells |
| US6451594B1 (en) | 1998-09-11 | 2002-09-17 | The Regents Of The University Of California | Recombinant adenovirus for tissue specific expression in heart |
| GB0112343D0 (en) | 2001-05-21 | 2001-07-11 | Norske Stats Oljeselskap | Well treatment |
| WO2004031359A2 (en) * | 2002-10-03 | 2004-04-15 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Method for regulating expression genes |
| WO2008104290A1 (en) * | 2007-02-27 | 2008-09-04 | Bayer Schering Pharma Aktiengesellschaft | H19 as a biomarker for ppara modulators |
| US8383346B2 (en) | 2008-06-13 | 2013-02-26 | Codexis, Inc. | Combined automated parallel synthesis of polynucleotide variants |
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| TR201818825T4 (tr) | 2019-01-21 |
| JP2020007332A (ja) | 2020-01-16 |
| US20200165604A1 (en) | 2020-05-28 |
| EP3467111B1 (en) | 2021-12-15 |
| PL3134526T3 (pl) | 2019-04-30 |
| CN117224687A (zh) | 2023-12-15 |
| HUE057484T2 (hu) | 2022-05-28 |
| JP6805304B2 (ja) | 2020-12-23 |
| DK3467111T3 (da) | 2022-03-14 |
| EP3134526B1 (en) | 2018-10-31 |
| WO2015162161A1 (en) | 2015-10-29 |
| PL3467111T3 (pl) | 2022-04-11 |
| US11371043B2 (en) | 2022-06-28 |
| JP2017514813A (ja) | 2017-06-08 |
| ES2706878T3 (es) | 2019-04-01 |
| EP3467111A1 (en) | 2019-04-10 |
| CA2945559A1 (en) | 2015-10-29 |
| US20170183652A1 (en) | 2017-06-29 |
| US20220315924A1 (en) | 2022-10-06 |
| CN106488777A (zh) | 2017-03-08 |
| JP6577960B2 (ja) | 2019-09-18 |
| HUE041700T2 (hu) | 2019-05-28 |
| US20220348920A1 (en) | 2022-11-03 |
| EP3134526A1 (en) | 2017-03-01 |
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