DK3133396T3 - METHODS OF TREATMENT WHEN USING AMMONIA-CLEANING MEDICINES - Google Patents

METHODS OF TREATMENT WHEN USING AMMONIA-CLEANING MEDICINES Download PDF

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Publication number
DK3133396T3
DK3133396T3 DK16176456.8T DK16176456T DK3133396T3 DK 3133396 T3 DK3133396 T3 DK 3133396T3 DK 16176456 T DK16176456 T DK 16176456T DK 3133396 T3 DK3133396 T3 DK 3133396T3
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DK
Denmark
Prior art keywords
hpn
pba
patient
pagn
ammonia
Prior art date
Application number
DK16176456.8T
Other languages
Danish (da)
English (en)
Inventor
Bruce Scharschmidt
Original Assignee
Horizon Therapeutics Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Horizon Therapeutics Llc filed Critical Horizon Therapeutics Llc
Priority claimed from EP09739263.3A external-priority patent/EP2330892B1/en
Application granted granted Critical
Publication of DK3133396T3 publication Critical patent/DK3133396T3/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6806Determination of free amino acids
    • G01N33/6812Assays for specific amino acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/08Hepato-biliairy disorders other than hepatitis
    • G01N2800/085Liver diseases, e.g. portal hypertension, fibrosis, cirrhosis, bilirubin
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/34Genitourinary disorders
    • G01N2800/347Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Emergency Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biophysics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DK16176456.8T 2008-08-29 2009-01-07 METHODS OF TREATMENT WHEN USING AMMONIA-CLEANING MEDICINES DK3133396T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9323408P 2008-08-29 2008-08-29
EP09739263.3A EP2330892B1 (en) 2008-04-29 2009-01-07 Methods of treatment using ammonia-scavenging drugs

Publications (1)

Publication Number Publication Date
DK3133396T3 true DK3133396T3 (en) 2018-12-03

Family

ID=45604478

Family Applications (1)

Application Number Title Priority Date Filing Date
DK16176456.8T DK3133396T3 (en) 2008-08-29 2009-01-07 METHODS OF TREATMENT WHEN USING AMMONIA-CLEANING MEDICINES

Country Status (10)

Country Link
JP (3) JP5577341B2 (es)
DK (1) DK3133396T3 (es)
ES (2) ES2593378T3 (es)
HR (2) HRP20161222T1 (es)
HU (2) HUE040503T2 (es)
LT (2) LT3133396T (es)
PL (1) PL2330892T3 (es)
PT (2) PT2330892T (es)
SI (1) SI3133396T1 (es)
TR (1) TR201816616T4 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2760479T3 (pl) 2011-09-30 2017-09-29 Horizon Therapeutics, Llc Lek wychwytujący azot do zastosowania w sposobie leczenia zaburzenia retencji azotu
PT2846791T (pt) * 2012-04-20 2017-05-25 Horizon Therapeutics Llc Métodos de monitorização terapêutica de profármacos de ácido fenilacético
SI2922576T1 (en) * 2012-11-21 2018-04-30 Horizon Therapeutics, Llc Procedures for the administration and evaluation of medicines for the elimination of nitrogen for the treatment of hepatitis encephalopathy
US9914692B2 (en) 2016-05-25 2018-03-13 Horizon Therapeutics, Llc Procedure for the preparation of 4-phenyl butyrate and uses thereof
US10668040B2 (en) 2017-09-11 2020-06-02 Horizon Therapeutics, Llc Treatment of urea cycle disorders in neonates and infants
US20220044801A1 (en) * 2018-10-04 2022-02-10 Atonarp Inc. Living body information acquisition system, health management server, and system

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4284647A (en) * 1980-03-31 1981-08-18 The Johns Hopkins University Process for waste nitrogen removal
DE69612755T2 (de) * 1995-02-07 2001-08-23 Brusilow Enterprises, Llc Triglyceride und ethylester von phenylalkansäuren und phenylalkensäuren zur behandlung verschiedener erkrankungen
US20070004805A1 (en) * 2005-07-01 2007-01-04 Navinta Llc Process for preparation of liquid dosage form containing sodium 4-phenylbutyrate

Also Published As

Publication number Publication date
JP2014102255A (ja) 2014-06-05
LT3133396T (lt) 2018-11-26
PL2330892T3 (pl) 2017-05-31
HRP20181877T1 (hr) 2019-01-11
JP5577341B2 (ja) 2014-08-20
JP2012501329A (ja) 2012-01-19
HUE040503T2 (hu) 2019-03-28
JP2012501451A (ja) 2012-01-19
HUE029912T2 (en) 2017-03-28
ES2695534T3 (es) 2019-01-08
PT2330892T (pt) 2016-09-05
SI3133396T1 (sl) 2018-12-31
LT2330892T (lt) 2016-11-25
PT3133396T (pt) 2018-12-07
ES2593378T3 (es) 2016-12-09
HRP20161222T1 (hr) 2017-02-10
TR201816616T4 (tr) 2018-11-21

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