DK3079A - Fremgangsmaade til fremstilling af antiatherosclerotisk virksomme forbindelser - Google Patents

Fremgangsmaade til fremstilling af antiatherosclerotisk virksomme forbindelser

Info

Publication number
DK3079A
DK3079A DK3079A DK3079A DK3079A DK 3079 A DK3079 A DK 3079A DK 3079 A DK3079 A DK 3079A DK 3079 A DK3079 A DK 3079A DK 3079 A DK3079 A DK 3079A
Authority
DK
Denmark
Prior art keywords
antiatherosclerotic
procedure
making
active compounds
compounds
Prior art date
Application number
DK3079A
Other languages
Danish (da)
English (en)
Inventor
F G Kathawala
J G Heider
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/881,780 external-priority patent/US4229463A/en
Priority claimed from US05/891,298 external-priority patent/US4194002A/en
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of DK3079A publication Critical patent/DK3079A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C243/00Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C04CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04BLIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B22/00Use of inorganic materials as active ingredients for mortars, concrete or artificial stone, e.g. accelerators, shrinkage compensating agents
    • C04B22/0013Boron compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C243/00Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
    • C07C243/24Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids
    • C07C243/26Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C243/28Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms to hydrogen atoms or to carbon atoms of a saturated carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/08Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16Tryptamines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/20Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/02Systems containing only non-condensed rings with a three-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Ceramic Engineering (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Materials Engineering (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Structural Engineering (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK3079A 1978-01-09 1979-01-03 Fremgangsmaade til fremstilling af antiatherosclerotisk virksomme forbindelser DK3079A (da)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US86782478A 1978-01-09 1978-01-09
US86781378A 1978-01-09 1978-01-09
US87283678A 1978-01-27 1978-01-27
US88178178A 1978-02-27 1978-02-27
US05/881,780 US4229463A (en) 1978-02-27 1978-02-27 Unsaturated fatty acid hydrazides
US05/891,298 US4194002A (en) 1978-03-29 1978-03-29 Cholesterol ester-reducing amides of hexahydroindolinols

Publications (1)

Publication Number Publication Date
DK3079A true DK3079A (da) 1979-07-10

Family

ID=27560330

Family Applications (1)

Application Number Title Priority Date Filing Date
DK3079A DK3079A (da) 1978-01-09 1979-01-03 Fremgangsmaade til fremstilling af antiatherosclerotisk virksomme forbindelser

Country Status (20)

Country Link
JP (1) JPS54109930A (de)
AU (1) AU529328B2 (de)
CA (1) CA1101871A (de)
CH (1) CH644842A5 (de)
CY (1) CY1294A (de)
DE (1) DE2856856A1 (de)
DK (1) DK3079A (de)
FI (1) FI790025A (de)
FR (1) FR2416885A1 (de)
GB (1) GB2012261B (de)
HK (1) HK80985A (de)
IE (1) IE48077B1 (de)
IL (1) IL56393A (de)
IT (1) IT1110603B (de)
KE (1) KE3546A (de)
MY (1) MY8500133A (de)
NZ (1) NZ189331A (de)
PT (1) PT69052A (de)
SE (1) SE446093B (de)
SG (1) SG42985G (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2937175A1 (de) * 1978-09-18 1980-03-27 Sandoz Ag Sekundaere amide von 2-alkynoylsaeuren, deren herstellung und deren pharmazeutischen zusammensetzungen
US4297349A (en) 1980-04-15 1981-10-27 Sandoz, Inc. Silicon-bearing carboxylic acids and amides
US4722927A (en) * 1986-04-28 1988-02-02 Warner-Lambert Company Pyrimidine amides of oleic or linoleic acid, composition containing them and their use as inhibitors of acyl-CoA cholesterol acyltransferase
FR2633617B1 (fr) * 1988-07-04 1991-02-08 Adir Nouveaux derives du benzocycloheptene, leur procede de preparation et les compositions pharmaceutiques les renfermant
US5290814A (en) * 1988-11-21 1994-03-01 Burroughs Wellcome Co. Anti-atherosclerotic diaryl compounds
EP2282735B1 (de) * 2008-04-21 2019-01-16 Signum Biosciences, Inc. Pp2a modulatoren zur behandlung von alzheimer, parkinson, diabetes

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1814334B2 (de) * 1967-12-21 1973-04-19 Sumitomo Chemical Co Ltd , Osaka (Japan) Fettsaeureamide und diese verbindungen enthaltende arzneimittel
FR2000945A1 (de) * 1968-01-30 1969-09-19 Sumitomo Chemical Co
JPS5835505B2 (ja) * 1976-01-09 1983-08-03 エーザイ株式会社 N−(α−メチル−ベンジル)−脂肪酸アミド

Also Published As

Publication number Publication date
JPS6323987B2 (de) 1988-05-18
JPS54109930A (en) 1979-08-29
IL56393A (en) 1982-08-31
AU4323379A (en) 1979-07-19
SG42985G (en) 1985-12-13
FR2416885B1 (de) 1983-04-22
GB2012261B (en) 1982-12-22
FI790025A (fi) 1979-07-10
IL56393A0 (en) 1979-03-12
AU529328B2 (en) 1983-06-02
SE446093B (sv) 1986-08-11
DE2856856A1 (de) 1979-07-12
PT69052A (fr) 1979-02-01
CH644842A5 (de) 1984-08-31
HK80985A (en) 1985-10-25
MY8500133A (en) 1985-12-31
SE7900142L (sv) 1979-07-10
IT7919059A0 (it) 1979-01-04
IT1110603B (it) 1985-12-23
IE48077B1 (en) 1984-09-19
KE3546A (en) 1985-07-19
CY1294A (en) 1985-10-18
GB2012261A (en) 1979-07-25
CA1101871A (en) 1981-05-26
NZ189331A (en) 1981-07-13
IE790031L (en) 1979-07-09
FR2416885A1 (fr) 1979-09-07

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment