DK3062607T3 - Fremgangsmåder til anvendelse af o-methyltransferase til biosyntetisk fremstilling af pterostilben - Google Patents
Fremgangsmåder til anvendelse af o-methyltransferase til biosyntetisk fremstilling af pterostilben Download PDFInfo
- Publication number
- DK3062607T3 DK3062607T3 DK14858679.5T DK14858679T DK3062607T3 DK 3062607 T3 DK3062607 T3 DK 3062607T3 DK 14858679 T DK14858679 T DK 14858679T DK 3062607 T3 DK3062607 T3 DK 3062607T3
- Authority
- DK
- Denmark
- Prior art keywords
- transpherase
- pterostilben
- methyl
- methods
- biosynthetic preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/22—Preparation of oxygen-containing organic compounds containing a hydroxy group aromatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1003—Transferases (2.) transferring one-carbon groups (2.1)
- C12N9/1007—Methyltransferases (general) (2.1.1.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1025—Acyltransferases (2.3)
- C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/93—Ligases (6)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y203/00—Acyltransferases (2.3)
- C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
- C12Y203/01095—Trihydroxystilbene synthase (2.3.1.95)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y602/00—Ligases forming carbon-sulfur bonds (6.2)
- C12Y602/01—Acid-Thiol Ligases (6.2.1)
- C12Y602/01012—4-Coumarate-CoA ligase (6.2.1.12)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361898899P | 2013-11-01 | 2013-11-01 | |
| PCT/US2014/063682 WO2015066609A1 (en) | 2013-11-01 | 2014-11-03 | Methods of using o-methyltransferase for biosynthetic production of pterostilbene |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3062607T3 true DK3062607T3 (da) | 2019-09-23 |
Family
ID=53005254
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK14858679.5T DK3062607T3 (da) | 2013-11-01 | 2014-11-03 | Fremgangsmåder til anvendelse af o-methyltransferase til biosyntetisk fremstilling af pterostilben |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US10370683B2 (da) |
| EP (1) | EP3062607B1 (da) |
| JP (1) | JP6522640B2 (da) |
| KR (1) | KR102350425B1 (da) |
| CN (1) | CN106102454B (da) |
| BR (1) | BR112016009734A2 (da) |
| CA (1) | CA2963219C (da) |
| DK (1) | DK3062607T3 (da) |
| ES (1) | ES2745092T3 (da) |
| HU (1) | HUE045463T2 (da) |
| MX (1) | MX369206B (da) |
| WO (1) | WO2015066609A1 (da) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102018422B1 (ko) * | 2017-05-31 | 2019-09-04 | 이화여자대학교 산학협력단 | 재조합 벡터, 형질전환체 및 이를 이용한 테로스틸벤의 생산 방법 |
| WO2020152579A1 (en) * | 2019-01-21 | 2020-07-30 | BOGONI, Sebastiano Stefano Giuseppe | Methylation process |
| CN110804618B (zh) * | 2019-11-25 | 2022-11-11 | 东北电力大学 | 定向进化构建高效转化白藜芦醇生产松芪的romt突变体 |
| CN112410356B (zh) * | 2020-11-10 | 2023-07-18 | 杭州鑫旺途科技有限公司 | 来源于三叶青的白藜芦醇合酶基因rs及其应用 |
| CN114807183B (zh) * | 2021-12-06 | 2023-06-02 | 西藏自治区农牧科学院农业研究所 | 一种青稞矢车菊素氧甲基转移酶基因的新用途 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5689046A (en) | 1987-09-30 | 1997-11-18 | Bayer Aktiengesellschaft | Stilbene synthase gene |
| GB0503657D0 (en) | 2005-02-22 | 2005-03-30 | Fluxome Sciences As | Metabolically engineered cells for the production of resveratrol or an oligomeric or glycosidically-bound derivative thereof |
| GB0614442D0 (en) | 2006-07-20 | 2006-08-30 | Fluxome Sciences As | Metabolically engineered cells for the production of pinosylvin |
| GB0806592D0 (en) * | 2008-04-11 | 2008-05-14 | Fluxome Sciences As | Conversion of stilbenoids |
| CN102120996A (zh) * | 2010-12-03 | 2011-07-13 | 西北农林科技大学 | 葡萄白藜芦醇-氧-甲基转移酶催化白藜芦醇生成紫檀芪的方法 |
| KR101520912B1 (ko) * | 2012-09-26 | 2015-05-18 | 한국생명공학연구원 | Ｒｏｍｔ 및 ｓｔｓ 유전자를 이용한 식물의 스틸벤 함량을 증가시키고 화색을 변화시키는 방법 |
| WO2015028324A2 (en) * | 2013-08-30 | 2015-03-05 | Evolva Sa | A method for producing modified resveratrol |
| CN103773704B (zh) * | 2013-12-25 | 2015-10-28 | 无锡新和源发酵技术研究院有限公司 | 一种利用o-甲基转移酶生物合成紫檀芹的方法 |
-
2014
- 2014-11-03 KR KR1020167014617A patent/KR102350425B1/ko active IP Right Grant
- 2014-11-03 HU HUE14858679A patent/HUE045463T2/hu unknown
- 2014-11-03 EP EP14858679.5A patent/EP3062607B1/en active Active
- 2014-11-03 CN CN201480072144.6A patent/CN106102454B/zh active Active
- 2014-11-03 DK DK14858679.5T patent/DK3062607T3/da active
- 2014-11-03 CA CA2963219A patent/CA2963219C/en active Active
- 2014-11-03 MX MX2016005717A patent/MX369206B/es active IP Right Grant
- 2014-11-03 WO PCT/US2014/063682 patent/WO2015066609A1/en active Application Filing
- 2014-11-03 ES ES14858679T patent/ES2745092T3/es active Active
- 2014-11-03 JP JP2016552436A patent/JP6522640B2/ja active Active
- 2014-11-03 US US15/033,705 patent/US10370683B2/en active Active
- 2014-11-03 BR BR112016009734A patent/BR112016009734A2/pt not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| HUE045463T2 (hu) | 2019-12-30 |
| JP2017502685A (ja) | 2017-01-26 |
| EP3062607A4 (en) | 2017-03-22 |
| BR112016009734A2 (pt) | 2017-09-12 |
| US10370683B2 (en) | 2019-08-06 |
| KR102350425B1 (ko) | 2022-01-11 |
| US20160273006A1 (en) | 2016-09-22 |
| CN106102454A (zh) | 2016-11-09 |
| MX369206B (es) | 2019-10-31 |
| MX2016005717A (es) | 2017-02-08 |
| EP3062607A1 (en) | 2016-09-07 |
| JP6522640B2 (ja) | 2019-05-29 |
| EP3062607B1 (en) | 2019-06-26 |
| CA2963219A1 (en) | 2015-05-07 |
| CA2963219C (en) | 2022-11-15 |
| KR20160079865A (ko) | 2016-07-06 |
| WO2015066609A1 (en) | 2015-05-07 |
| ES2745092T3 (es) | 2020-02-27 |
| CN106102454B (zh) | 2020-07-31 |
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