DK3034512T3 - A process for the preparation of iron (III)-casein-N-acetyl-aspartylated complexes and their use in pharmaceutical compositions - Google Patents

A process for the preparation of iron (III)-casein-N-acetyl-aspartylated complexes and their use in pharmaceutical compositions Download PDF

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Publication number
DK3034512T3
DK3034512T3 DK14386034.4T DK14386034T DK3034512T3 DK 3034512 T3 DK3034512 T3 DK 3034512T3 DK 14386034 T DK14386034 T DK 14386034T DK 3034512 T3 DK3034512 T3 DK 3034512T3
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DK
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Prior art keywords
acetyl
casein
iron
aspartylated
solution
Prior art date
Application number
DK14386034.4T
Other languages
Danish (da)
English (en)
Inventor
Ioulia Tseti
Original Assignee
Ioulia Tseti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ioulia Tseti filed Critical Ioulia Tseti
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Publication of DK3034512T3 publication Critical patent/DK3034512T3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4732—Casein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/26—Iron; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Inorganic Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK14386034.4T 2014-12-19 2014-12-19 A process for the preparation of iron (III)-casein-N-acetyl-aspartylated complexes and their use in pharmaceutical compositions DK3034512T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP14386034.4A EP3034512B1 (en) 2014-12-19 2014-12-19 A process for producing iron (III) casein N-acetyl-aspartylated complexes and use thereof in pharmaceutical compositions

Publications (1)

Publication Number Publication Date
DK3034512T3 true DK3034512T3 (en) 2018-01-15

Family

ID=52354737

Family Applications (1)

Application Number Title Priority Date Filing Date
DK14386034.4T DK3034512T3 (en) 2014-12-19 2014-12-19 A process for the preparation of iron (III)-casein-N-acetyl-aspartylated complexes and their use in pharmaceutical compositions

Country Status (30)

Country Link
US (1) US20170340747A1 (enExample)
EP (1) EP3034512B1 (enExample)
AP (1) AP2017009801A0 (enExample)
AU (1) AU2015365885B2 (enExample)
BR (1) BR112017006621B1 (enExample)
CA (1) CA2959226C (enExample)
CL (1) CL2017001611A1 (enExample)
CO (1) CO2017003313A2 (enExample)
CY (1) CY1120037T1 (enExample)
DK (1) DK3034512T3 (enExample)
EA (1) EA031968B1 (enExample)
ES (1) ES2655238T3 (enExample)
GE (2) GEAP201914514A (enExample)
HR (1) HRP20171965T1 (enExample)
HU (1) HUE035302T2 (enExample)
IL (1) IL251449B (enExample)
LT (1) LT3034512T (enExample)
MX (1) MX374777B (enExample)
MY (1) MY185391A (enExample)
NO (1) NO3034512T3 (enExample)
PE (1) PE20180660A1 (enExample)
PH (1) PH12017500391B1 (enExample)
PL (1) PL3034512T3 (enExample)
PT (1) PT3034512T (enExample)
RS (1) RS56714B1 (enExample)
SA (1) SA517381261B1 (enExample)
SG (1) SG11201702593TA (enExample)
SI (1) SI3034512T1 (enExample)
SM (1) SMT201800008T1 (enExample)
WO (1) WO2016096203A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR1009589B (el) 2018-04-05 2019-09-11 Ιουλια Κλεωνος Τσετη Φαρμακευτικο σκευασμα για την αντιμετωπιση της αναιμιας, σε καταλληλο περιεκτη, που διατηρει στεγανα διαχωρισμενα μεταξυ τους τα δραστικα συστατικα: συμπλοκο του τρισθενους σιδηρου με ν-ακετυλο-l-ασπαρτικη καζεϊνη και πενταϋδρικο φυλλινικο ασβεστιο
CN116655512A (zh) * 2023-05-31 2023-08-29 江苏阿尔法药业股份有限公司 一种卡托普利的制备工艺

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB910321A (en) 1960-02-25 1962-11-14 Olivier Paul Gaudin Improvements in and relating to a process for preparing ferrous salts of aspartic acid and medicines containing these salts
IT1150213B (it) 1982-03-02 1986-12-10 Italfarmaco Spa Derivati di ferro biodisponibile esenti da gastrolesivita',procentimento di preparazione e relative composizioni farmaceutiche
IT1207996B (it) 1986-03-18 1989-06-01 Magis Farmaceutici Composti contenenti ferro biodisponibile, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono.
GB9621273D0 (en) 1996-10-11 1996-11-27 Cortecs Ltd Therapeutic method
IT1297022B1 (it) 1997-12-24 1999-08-03 Chemi Spa Complesso di ferro-succinilcaseina, processo per la sua preparazione e composizioni farmaceutiche che lo contengono
ITMO20040200A1 (it) 2004-07-29 2004-10-29 Biofer Spa Processo per la produzione di complessi ferro succinilcaseina e ferro casein acetil aspartilato e loro utilizzato nelle relative composizioni farmaceutiche.

Also Published As

Publication number Publication date
CA2959226C (en) 2018-10-09
EA031968B1 (ru) 2019-03-29
NO3034512T3 (enExample) 2018-05-05
RS56714B1 (sr) 2018-03-30
PT3034512T (pt) 2018-01-11
EP3034512A1 (en) 2016-06-22
SMT201800008T1 (it) 2018-03-08
HRP20171965T1 (hr) 2018-02-23
PE20180660A1 (es) 2018-04-17
CY1120037T1 (el) 2018-12-12
CL2017001611A1 (es) 2018-01-26
AU2015365885A1 (en) 2017-03-16
MY185391A (en) 2021-05-17
GEAP201914514A (en) 2019-10-25
IL251449A0 (en) 2017-05-29
PH12017500391A1 (en) 2017-07-17
EP3034512B1 (en) 2017-12-06
HUE035302T2 (en) 2018-05-02
MX374777B (es) 2025-03-06
EA201790902A1 (ru) 2017-10-31
SG11201702593TA (en) 2017-04-27
PH12017500391B1 (en) 2021-12-15
SI3034512T1 (en) 2018-04-30
SA517381261B1 (ar) 2017-12-20
WO2016096203A1 (en) 2016-06-23
ES2655238T3 (es) 2018-02-19
MX2017008100A (es) 2017-10-31
CA2959226A1 (en) 2016-06-23
IL251449B (en) 2019-02-28
PL3034512T3 (pl) 2018-03-30
US20170340747A1 (en) 2017-11-30
CO2017003313A2 (es) 2017-07-28
AU2015365885B2 (en) 2018-11-15
BR112017006621B1 (pt) 2023-11-07
BR112017006621A2 (pt) 2017-12-19
LT3034512T (lt) 2018-01-25
GEP20207081B (en) 2020-03-25
AP2017009801A0 (en) 2017-03-31

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