DK301789A - Neplanocin-derivater - Google Patents

Neplanocin-derivater Download PDF

Info

Publication number
DK301789A
DK301789A DK301789A DK301789A DK301789A DK 301789 A DK301789 A DK 301789A DK 301789 A DK301789 A DK 301789A DK 301789 A DK301789 A DK 301789A DK 301789 A DK301789 A DK 301789A
Authority
DK
Denmark
Prior art keywords
neplanocin derivatives
neplanocin
derivatives
Prior art date
Application number
DK301789A
Other languages
Danish (da)
English (en)
Other versions
DK301789D0 (da
Inventor
Esa T Jarvi
James R Mccarthy
Nellikunja J Prakash
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of DK301789D0 publication Critical patent/DK301789D0/da
Publication of DK301789A publication Critical patent/DK301789A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK301789A 1988-06-20 1989-06-19 Neplanocin-derivater DK301789A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US20924588A 1988-06-20 1988-06-20

Publications (2)

Publication Number Publication Date
DK301789D0 DK301789D0 (da) 1989-06-19
DK301789A true DK301789A (da) 1989-12-21

Family

ID=22777970

Family Applications (1)

Application Number Title Priority Date Filing Date
DK301789A DK301789A (da) 1988-06-20 1989-06-19 Neplanocin-derivater

Country Status (20)

Country Link
EP (1) EP0347852B1 (ja)
JP (1) JP2967998B2 (ja)
KR (1) KR0139808B1 (ja)
CN (1) CN1040031A (ja)
AR (1) AR244688A1 (ja)
AT (1) ATE126800T1 (ja)
AU (1) AU612854B2 (ja)
CA (1) CA1339646C (ja)
DE (1) DE68923913T2 (ja)
DK (1) DK301789A (ja)
ES (1) ES2078904T3 (ja)
FI (1) FI91156C (ja)
GR (1) GR3017794T3 (ja)
HU (1) HUT50194A (ja)
IE (1) IE66980B1 (ja)
IL (1) IL90639A (ja)
NO (1) NO168108C (ja)
NZ (1) NZ229596A (ja)
PT (1) PT90903B (ja)
ZA (1) ZA894534B (ja)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5521162A (en) * 1987-08-26 1996-05-28 Merrell Pharmaceuticals Inc. Aristeromycin analogues of 4',5'-didehydro-5'-fluoro-adenosine and methods of treating neoplastic and viral disease conditions
GB8815265D0 (en) * 1988-06-27 1988-08-03 Wellcome Found Therapeutic nucleosides
HU204843B (en) * 1988-09-27 1992-02-28 Merrell Dow Pharma Process for producing 2'-halogen-methylidene adenosine derivatives and pharmaceutical compositions comprising same
JPH0421682A (ja) * 1990-05-11 1992-01-24 Asahi Chem Ind Co Ltd 2―フルオロネプラノシンaおよびその製造法
GB9205071D0 (en) * 1992-03-09 1992-04-22 Wellcome Found Therapeutic nucleosides
US5399580A (en) * 1993-03-08 1995-03-21 Burroughs Wellcome Co. Therapeutic nucleosides-uses
GB9600142D0 (en) * 1996-01-05 1996-03-06 Wellcome Found Chemical compounds
CA2375383C (en) * 1999-06-09 2008-07-29 Anticancer, Inc. Modulators of methylation for control of bacterial virulence
ATE490788T1 (de) 2003-04-25 2010-12-15 Gilead Sciences Inc Antivirale phosphonate analoge
EP1778251B1 (en) * 2004-07-27 2011-04-13 Gilead Sciences, Inc. Nucleoside phosphonate conjugates as anti hiv agents
AU2009268681B2 (en) 2008-07-08 2014-10-02 Gilead Sciences, Inc. Salts of HIV inhibitor compounds
JP2012503651A (ja) * 2008-09-26 2012-02-09 エージェンシー フォー サイエンス,テクノロジー アンド リサーチ 3−デアザネプラノシン誘導体
EP3960740B1 (en) 2017-08-01 2023-11-15 Gilead Sciences, Inc. Crystalline forms of ethyl ((s)-((((2r,5r)-5-(6-amino-9h-purin-9-yl)-4-fluoro-2,5-dihydrofuran-2-yl)oxy)methyl)(phenoxy)phosphoryl)-l-alaninate (gs-9131) vanillate for treating viral infections

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU192741B (en) * 1978-05-25 1987-07-28 Toyo Jozo Kk Process for producing new neplanocin antibiotics
DE3148363A1 (de) * 1980-12-12 1982-09-16 Toyo Jozo K.K., Shizuoka Neplanocin a-derivate
IT1188654B (it) * 1985-04-15 1988-01-20 Toyo Jozo Kk Coniugato nucleo side-fosfolipide
DE3778626D1 (de) * 1986-09-27 1992-06-04 Toyo Jozo Kk Nukleosid-phospholipid-konjugat.

Also Published As

Publication number Publication date
AU612854B2 (en) 1991-07-18
IE891986L (en) 1989-12-20
FI893003A (fi) 1989-12-21
DE68923913D1 (de) 1995-09-28
EP0347852A3 (en) 1991-09-11
PT90903B (pt) 1994-12-30
IE66980B1 (en) 1996-02-21
NZ229596A (en) 1990-12-21
KR910000734A (ko) 1991-01-30
IL90639A (en) 1992-12-01
NO168108B (no) 1991-10-07
CN1040031A (zh) 1990-02-28
HUT50194A (en) 1989-12-28
EP0347852A2 (en) 1989-12-27
NO892543D0 (no) 1989-06-19
DE68923913T2 (de) 1996-01-11
FI91156B (fi) 1994-02-15
NO892543L (no) 1989-12-21
DK301789D0 (da) 1989-06-19
JPH0240369A (ja) 1990-02-09
AU3651789A (en) 1989-12-21
FI893003A0 (fi) 1989-06-19
PT90903A (pt) 1989-12-29
IL90639A0 (en) 1990-01-18
ES2078904T3 (es) 1996-01-01
ATE126800T1 (de) 1995-09-15
AR244688A1 (es) 1993-11-30
EP0347852B1 (en) 1995-08-23
KR0139808B1 (ko) 1998-06-01
ZA894534B (en) 1990-03-28
GR3017794T3 (en) 1996-01-31
FI91156C (fi) 1994-05-25
JP2967998B2 (ja) 1999-10-25
CA1339646C (en) 1998-01-27
NO168108C (no) 1992-01-15

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Legal Events

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AHS Application shelved for other reasons than non-payment