DK300181A - Fremgangsmaade til fremstilling af 2(3h)-indoloner - Google Patents
Fremgangsmaade til fremstilling af 2(3h)-indolonerInfo
- Publication number
- DK300181A DK300181A DK300181A DK300181A DK300181A DK 300181 A DK300181 A DK 300181A DK 300181 A DK300181 A DK 300181A DK 300181 A DK300181 A DK 300181A DK 300181 A DK300181 A DK 300181A
- Authority
- DK
- Denmark
- Prior art keywords
- indolons
- procedure
- group
- preparation
- indolone
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/10—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/34—Oxygen atoms in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/38—Oxygen atoms in positions 2 and 3, e.g. isatin
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/180,551 US4314944A (en) | 1980-08-22 | 1980-08-22 | 4-Aminoalkyl-7-hydroxy-2(3H)-indolones |
US18055180 | 1980-08-22 |
Publications (3)
Publication Number | Publication Date |
---|---|
DK300181A true DK300181A (da) | 1982-02-23 |
DK154293B DK154293B (da) | 1988-10-31 |
DK154293C DK154293C (da) | 1989-03-28 |
Family
ID=22660875
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK300181A DK154293C (da) | 1980-08-22 | 1981-07-07 | Analogifremgangsmaade til fremstilling af 2(3h)-indoloner |
Country Status (11)
Country | Link |
---|---|
US (1) | US4314944A (da) |
EP (1) | EP0046666B1 (da) |
JP (1) | JPS5770866A (da) |
AT (1) | ATE19395T1 (da) |
AU (1) | AU542492B2 (da) |
CA (1) | CA1161047A (da) |
DE (1) | DE3174461D1 (da) |
DK (1) | DK154293C (da) |
GR (1) | GR75312B (da) |
IE (1) | IE51676B1 (da) |
MY (1) | MY8700935A (da) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4442111A (en) * | 1981-07-25 | 1984-04-10 | Dr. Karl Thomae Gesellschaft Mit Beschrankter Haftung | Antithrombotic sulfimino and sulfoximino indolinones-2 |
US4588740A (en) * | 1982-12-07 | 1986-05-13 | Smithkline Beckman Corporation | Pharmaceutical methods using 4-aminoalkyl-2(3H)-indolones |
US4452808A (en) * | 1982-12-07 | 1984-06-05 | Smithkline Beckman Corporation | 4-Aminoalkyl-2(3H)-indolones |
EP0163607B1 (de) * | 1984-05-28 | 1989-11-08 | Ciba-Geigy Ag | Mittel zum Schützen von Kulturpflanzen vor der phytotoxischen Wirkung von herbizid wirksamen Chloracetaniliden |
US4593106A (en) * | 1984-06-04 | 1986-06-03 | Smithkline Beckman Corporation | 4-[2-(dialkylamino)ethyl]-7-hydroxyisatins |
DE3430310A1 (de) * | 1984-08-15 | 1986-02-27 | Schering AG, Berlin und Bergkamen, 1000 Berlin | Neue dopamin-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
US4958026A (en) * | 1984-08-15 | 1990-09-18 | Schering Aktiengesllschaft | Novel dopamine derivatives, processes for their preparation, and their use as medicinal agents |
US4554284A (en) * | 1984-09-12 | 1985-11-19 | Smithkline Beckman Corporation | 7-(2-Aminoethyl)-1,3-benzthia- or oxa-zol-2(3H)-ones |
US4554287A (en) * | 1984-09-12 | 1985-11-19 | Smithkline Beckman Corporation | Antihypertensive 7-[2-(dialkylamino)ethyl]-4-hydroxy-1,3-benzimidazol-2-ones |
GB9210632D0 (en) * | 1992-05-19 | 1992-07-01 | Fisons Plc | Compounds |
IE914003A1 (en) * | 1990-11-20 | 1992-05-20 | Astra Pharma Prod | Biologically Active Amines |
GB9300309D0 (en) * | 1993-01-08 | 1993-03-03 | Smithkline Beecham Plc | Process |
US5611815A (en) * | 1994-12-08 | 1997-03-18 | Heartstream, Inc. | Defibrillator with training features |
TW356468B (en) * | 1995-09-15 | 1999-04-21 | Astra Pharma Prod | Benzothiazolone compounds useful as beta2-adrenoreceptor and dopamine DA2 receptor agonists process for preparing same and pharmaceutical compositions containing same |
AR004523A1 (es) | 1995-11-06 | 1998-12-16 | American Home Prod | 2-(AMINOMETIL)-3,4,7,9-TETRAHIDRO-2H-PIRANO-[2,3e] INDOL-8-ONAS Y COMPOSICIONES FARMACEUTICAS QUE LAS COMPRENDEN |
GB9526511D0 (en) * | 1995-12-23 | 1996-02-28 | Astra Pharma Prod | Pharmaceutically active compounds |
FR2752071B1 (fr) | 1996-07-30 | 1998-12-18 | Thomson Csf | Lecteur pour cartes a puce a interface homme-machine amelioree |
US5817690A (en) * | 1996-08-27 | 1998-10-06 | American Home Products Corporation | 4-aminoethoxy indolone derivatives |
ES2179362T3 (es) * | 1996-08-27 | 2003-01-16 | Wyeth Corp | Derivados de 4-aminoetoxi indolona. |
US5750556A (en) * | 1996-10-30 | 1998-05-12 | American Home Products Corporation | 2-(aminomethyl)-3,4,7,9-tetrahydro-2H-pyrano- 2,3-E!indol-8-ones and derivatives |
TW200811182A (en) * | 2006-05-25 | 2008-03-01 | Wyeth Corp | Oxindoledioxans, synthesis thereof, and intermediates thereto |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH421107A (de) * | 1963-06-04 | 1966-09-30 | Sandoz Ag | Verfahren zur Herstellung neuer heterocyclischer Verbindungen |
GB1237008A (en) * | 1968-12-18 | 1971-06-30 | Pfizer Ltd | Novel indoline derivatives |
JPS539227B2 (da) | 1973-12-26 | 1978-04-04 | ||
US4053613A (en) * | 1975-09-17 | 1977-10-11 | E. R. Squibb & Sons, Inc. | 1,3,thiazolinyl and 1,3 thiazinyl substituted indolinones |
JPS5825673B2 (ja) * | 1976-03-31 | 1983-05-28 | 大塚製薬株式会社 | オキシインド−ル誘導体 |
JPS5840539B2 (ja) * | 1976-03-31 | 1983-09-06 | 大塚製薬株式会社 | α−置換アミノアルカノイルオキシインド−ル誘導体 |
JPS5919537B2 (ja) * | 1976-08-02 | 1984-05-07 | 大塚製薬株式会社 | オキシインド−ル誘導体 |
-
1980
- 1980-08-22 US US06/180,551 patent/US4314944A/en not_active Expired - Lifetime
-
1981
- 1981-07-07 DK DK300181A patent/DK154293C/da not_active IP Right Cessation
- 1981-08-18 JP JP56130034A patent/JPS5770866A/ja active Pending
- 1981-08-19 GR GR65816A patent/GR75312B/el unknown
- 1981-08-21 IE IE1922/81A patent/IE51676B1/en unknown
- 1981-08-21 AT AT81303814T patent/ATE19395T1/de not_active IP Right Cessation
- 1981-08-21 DE DE8181303814T patent/DE3174461D1/de not_active Expired
- 1981-08-21 EP EP81303814A patent/EP0046666B1/en not_active Expired
- 1981-12-22 CA CA000393012A patent/CA1161047A/en not_active Expired
- 1981-12-30 AU AU79094/81A patent/AU542492B2/en not_active Ceased
-
1987
- 1987-12-30 MY MY935/87A patent/MY8700935A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
EP0046666A1 (en) | 1982-03-03 |
GR75312B (da) | 1984-07-13 |
EP0046666B1 (en) | 1986-04-23 |
CA1161047A (en) | 1984-01-24 |
JPS5770866A (en) | 1982-05-01 |
IE811922L (en) | 1982-02-22 |
AU542492B2 (en) | 1985-02-21 |
AU7909481A (en) | 1983-07-07 |
ATE19395T1 (de) | 1986-05-15 |
MY8700935A (en) | 1987-12-31 |
IE51676B1 (en) | 1987-02-04 |
DK154293C (da) | 1989-03-28 |
DE3174461D1 (en) | 1986-05-28 |
US4314944A (en) | 1982-02-09 |
DK154293B (da) | 1988-10-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PBP | Patent lapsed |