DK29789D0 - 5-substituerede 1-(4-(1-pyrrolidinyl)-2-butynyl)-2-pyrrolidoner og beslaegtede forbindelser, deres fremstilling og anvendelse som laegemidler - Google Patents
5-substituerede 1-(4-(1-pyrrolidinyl)-2-butynyl)-2-pyrrolidoner og beslaegtede forbindelser, deres fremstilling og anvendelse som laegemidlerInfo
- Publication number
- DK29789D0 DK29789D0 DK029789A DK29789A DK29789D0 DK 29789 D0 DK29789 D0 DK 29789D0 DK 029789 A DK029789 A DK 029789A DK 29789 A DK29789 A DK 29789A DK 29789 D0 DK29789 D0 DK 29789D0
- Authority
- DK
- Denmark
- Prior art keywords
- pyrrolidones
- butynyl
- pyrrolidinyl
- medicines
- substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
- C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D207/28—2-Pyrrolidone-5- carboxylic acids; Functional derivatives thereof, e.g. esters, nitriles
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hospice & Palliative Care (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Psychiatry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/148,268 US4772601A (en) | 1988-01-25 | 1988-01-25 | 5-Substituted 1-(4-(1-pyrrolidinyl)-2-butynyl)-2-pyrrolidinones, pharmaceutical compositions and use |
Publications (2)
Publication Number | Publication Date |
---|---|
DK29789D0 true DK29789D0 (da) | 1989-01-24 |
DK29789A DK29789A (da) | 1989-07-26 |
Family
ID=22525034
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK029789A DK29789A (da) | 1988-01-25 | 1989-01-24 | 5-substituerede 1-(4-(1-pyrrolidinyl)-2-butynyl)-2-pyrrolidoner og beslaegtede forbindelser, deres fremstilling og anvendelse som laegemidler |
Country Status (6)
Country | Link |
---|---|
US (1) | US4772601A (da) |
EP (1) | EP0325984A3 (da) |
JP (1) | JPH02138252A (da) |
DK (1) | DK29789A (da) |
IE (1) | IE890201L (da) |
PT (1) | PT89522A (da) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2603888B1 (fr) * | 1986-09-16 | 1990-12-21 | Panmedica Sa | Esters d'amino acides du trimethyl cyclohexanol, procede de preparation et utilisation comme medicaments |
US5236946A (en) * | 1986-09-16 | 1993-08-17 | Panmedica S.A. | Amino acid esters of cycloaliphatic alcohols and their use in treating lipemic disorders |
IT1215587B (it) * | 1987-06-26 | 1990-02-14 | Roussel Maestretti Spa | Derivati della 1-benzoil2-oxo 5-alcossi pirrolidina, loro procedimento di preparazione e loro impiego come sostanza medicinale. |
GB8811410D0 (en) * | 1988-05-13 | 1988-06-15 | Unilever Plc | Treatment of skin disorders |
EP0367393A3 (en) * | 1988-10-31 | 1991-03-27 | Takeda Chemical Industries, Ltd. | New heterocyclic compounds, production and use thereof |
IT1244507B (it) * | 1991-04-11 | 1994-07-15 | Sigma Tau Ind Farmaceuti | Derivati dell'acido piroglutammico quali attivatori dei processi di apprendimento e della memoria e composizioni farmaceutiche comprendenti tali composti |
AU2007271182B2 (en) * | 2006-07-06 | 2012-03-15 | Glaxo Group Limited | Substituted N-phenylmethyl -5-oxo-proline-2-amides as P2X7-receptor antagonists and their methods of use |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB833820A (en) * | 1957-10-17 | 1960-04-27 | Beecham Res Lab | Improvements in or relating to the preparation of pyrrolidyl esters and quaternary compounds thereof |
FR3637M (fr) * | 1964-05-26 | 1965-10-25 | Ile Auguil Soc Civ | Médicament hyptonseur, analgésique et sédatif a base d'(oxo-2 pyrrolidino-1)-1 pyrrolidino-1)-4 butyne-2. |
FR1517697A (fr) * | 1966-03-15 | 1968-03-22 | Leanord | Nouveaux composés esters et amides de l'acide pyroglutamique, procédé pour leur fabrication, solvants à base de tels composés, et procédé d'extraction avec de tels solvants |
FR2273533A1 (fr) * | 1974-06-04 | 1976-01-02 | Ferlux Sa | Nouveaux derives n-substitues d'acides pyrrolidones-2 carboxyliques-5 |
DE2556326A1 (de) * | 1975-12-13 | 1977-06-23 | Hoechst Ag | Neue pyrrolidone und verfahren zu ihrer herstellung |
DE2528664A1 (de) * | 1975-06-27 | 1977-01-13 | Hoechst Ag | Pyrrolidone und verfahren zu ihrer herstellung |
JPS5283368A (en) * | 1975-12-27 | 1977-07-12 | Tanabe Seiyaku Co Ltd | Synthesis of 2-pyprolidone derivatives |
JPS5283367A (en) * | 1975-12-27 | 1977-07-12 | Tanabe Seiyaku Co Ltd | Synthesis of 2-pyrrolidone derivatives |
DE3336024A1 (de) * | 1983-10-04 | 1985-04-18 | Boehringer Ingelheim KG, 6507 Ingelheim | 4-amino-l-benzyl-pyrrolidinone und ihre saeureadditionssalze, verfahren zu ihrer herstellung und arzneimittel |
JPS6330466A (ja) * | 1986-07-24 | 1988-02-09 | Hisamitsu Pharmaceut Co Inc | アザシクロアルカン化合物 |
-
1988
- 1988-01-25 US US07/148,268 patent/US4772601A/en not_active Expired - Lifetime
-
1989
- 1989-01-17 EP EP19890100673 patent/EP0325984A3/en not_active Withdrawn
- 1989-01-24 PT PT89522A patent/PT89522A/pt not_active Application Discontinuation
- 1989-01-24 DK DK029789A patent/DK29789A/da not_active Application Discontinuation
- 1989-01-24 JP JP1013318A patent/JPH02138252A/ja active Pending
- 1989-01-24 IE IE890201A patent/IE890201L/xx unknown
Also Published As
Publication number | Publication date |
---|---|
PT89522A (pt) | 1989-10-04 |
EP0325984A2 (en) | 1989-08-02 |
US4772601A (en) | 1988-09-20 |
DK29789A (da) | 1989-07-26 |
EP0325984A3 (en) | 1991-01-02 |
IE890201L (en) | 1989-07-25 |
JPH02138252A (ja) | 1990-05-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ATS | Application withdrawn |