FR2273533A1 - Nouveaux derives n-substitues d'acides pyrrolidones-2 carboxyliques-5 - Google Patents

Nouveaux derives n-substitues d'acides pyrrolidones-2 carboxyliques-5

Info

Publication number
FR2273533A1
FR2273533A1 FR7419152A FR7419152A FR2273533A1 FR 2273533 A1 FR2273533 A1 FR 2273533A1 FR 7419152 A FR7419152 A FR 7419152A FR 7419152 A FR7419152 A FR 7419152A FR 2273533 A1 FR2273533 A1 FR 2273533A1
Authority
FR
France
Prior art keywords
normolipemics
substd
carboxylic acid
analgesics
pyrrolidone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7419152A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ferlux SA
Original Assignee
Ferlux SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferlux SA filed Critical Ferlux SA
Priority to FR7419152A priority Critical patent/FR2273533A1/fr
Publication of FR2273533A1 publication Critical patent/FR2273533A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D207/28—2-Pyrrolidone-5- carboxylic acids; Functional derivatives thereof, e.g. esters, nitriles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
FR7419152A 1974-06-04 1974-06-04 Nouveaux derives n-substitues d'acides pyrrolidones-2 carboxyliques-5 Withdrawn FR2273533A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7419152A FR2273533A1 (fr) 1974-06-04 1974-06-04 Nouveaux derives n-substitues d'acides pyrrolidones-2 carboxyliques-5

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7419152A FR2273533A1 (fr) 1974-06-04 1974-06-04 Nouveaux derives n-substitues d'acides pyrrolidones-2 carboxyliques-5

Publications (1)

Publication Number Publication Date
FR2273533A1 true FR2273533A1 (fr) 1976-01-02

Family

ID=9139572

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7419152A Withdrawn FR2273533A1 (fr) 1974-06-04 1974-06-04 Nouveaux derives n-substitues d'acides pyrrolidones-2 carboxyliques-5

Country Status (1)

Country Link
FR (1) FR2273533A1 (fr)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4652567A (en) * 1985-03-13 1987-03-24 Hoechst-Roussel Pharmaceuticals Inc. Benzo(c)-1,5-naphthyridines useful for treating a patient having drug induced memory impairment in need of memory enhancement
US4742061A (en) * 1985-03-13 1988-05-03 Hoechst-Roussel Pharmaceuticals Inc. Benzoc[c]-1,5-naphthyridines and related compounds as memory enhancing agents
EP0325984A2 (fr) * 1988-01-25 1989-08-02 Hoechst-Roussel Pharmaceuticals Incorporated 1-/4-(1-pyrolidinyl)-2-butynyl/-2-pyrrolidones 5-substituées et ses dérivés, procédé pour leur préparation et leur utilisation comme médicaments
WO2008003697A1 (fr) * 2006-07-06 2008-01-10 Glaxo Group Limited N-phenylmethyl -5-oxo-proline-2-amides substitués tenant lieu d'antagonistes du récepteur p2x7 et procédés d'utilisation
WO2019185868A1 (fr) * 2018-03-29 2019-10-03 Centre National De La Recherche Scientifique Modulateurs p2rx7 utilisés en thérapie

Cited By (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4652567A (en) * 1985-03-13 1987-03-24 Hoechst-Roussel Pharmaceuticals Inc. Benzo(c)-1,5-naphthyridines useful for treating a patient having drug induced memory impairment in need of memory enhancement
US4742061A (en) * 1985-03-13 1988-05-03 Hoechst-Roussel Pharmaceuticals Inc. Benzoc[c]-1,5-naphthyridines and related compounds as memory enhancing agents
EP0325984A2 (fr) * 1988-01-25 1989-08-02 Hoechst-Roussel Pharmaceuticals Incorporated 1-/4-(1-pyrolidinyl)-2-butynyl/-2-pyrrolidones 5-substituées et ses dérivés, procédé pour leur préparation et leur utilisation comme médicaments
EP0325984A3 (fr) * 1988-01-25 1991-01-02 Hoechst-Roussel Pharmaceuticals Incorporated 1-/4-(1-pyrolidinyl)-2-butynyl/-2-pyrrolidones 5-substituées et ses dérivés, procédé pour leur préparation et leur utilisation comme médicaments
WO2008003697A1 (fr) * 2006-07-06 2008-01-10 Glaxo Group Limited N-phenylmethyl -5-oxo-proline-2-amides substitués tenant lieu d'antagonistes du récepteur p2x7 et procédés d'utilisation
JP2009542595A (ja) * 2006-07-06 2009-12-03 グラクソ グループ リミテッド Ｐ２ｘ７受容体アンタゴニストとしての置換ｎ−フェニルメチル−５−オキソ−プロリン−２−アミドおよびそれらの使用方法
US7718693B2 (en) 2006-07-06 2010-05-18 Glaxo Group Limited Receptor antagonists and their methods of use
US8048907B2 (en) 2006-07-06 2011-11-01 Glaxo Group Limited Receptor antagonists and their methods of use
EA016076B1 (ru) * 2006-07-06 2012-01-30 Глэксо Груп Лимитед Замещенные n-фенилметил-5-оксопролин-2-амиды в качестве антагонистов р2х7-рецептора и способы их применения
AU2007271182B2 (en) * 2006-07-06 2012-03-15 Glaxo Group Limited Substituted N-phenylmethyl -5-oxo-proline-2-amides as P2X7-receptor antagonists and their methods of use
WO2019185868A1 (fr) * 2018-03-29 2019-10-03 Centre National De La Recherche Scientifique Modulateurs p2rx7 utilisés en thérapie
CN112512520A (zh) * 2018-03-29 2021-03-16 国家科学研究中心 治疗中的p2rx7调节剂
JP2021520405A (ja) * 2018-03-29 2021-08-19 サントル ナショナル ドゥ ラ ルシェルシュ シアンティフィック 療法におけるｐ２ｒｘ７モジュレーター
CN112512520B (zh) * 2018-03-29 2023-10-24 国家科学研究中心 治疗中的p2rx7调节剂
IL277602B1 (en) * 2018-03-29 2024-02-01 Centre Nat Rech Scient P2RX7 modulators in therapy
US11919854B2 (en) 2018-03-29 2024-03-05 Centre National De La Recherche Scientifique P2RX7 modulators in therapy
IL277602B2 (en) * 2018-03-29 2024-06-01 Centre Nat Rech Scient P2RX7 modulators in therapy

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