DK296682A - Oploeselig lever-uricase fremgangsmaade til dens fremstilling og anvendelse - Google Patents

Oploeselig lever-uricase fremgangsmaade til dens fremstilling og anvendelse Download PDF

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Publication number
DK296682A
DK296682A DK296682A DK296682A DK296682A DK 296682 A DK296682 A DK 296682A DK 296682 A DK296682 A DK 296682A DK 296682 A DK296682 A DK 296682A DK 296682 A DK296682 A DK 296682A
Authority
DK
Denmark
Prior art keywords
soluble
uricase
supplier
procedure
manufacturing
Prior art date
Application number
DK296682A
Other languages
English (en)
Other versions
DK159688B (da
DK159688C (da
Inventor
M Gloger
J Heinle
H Schlumberger
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of DK296682A publication Critical patent/DK296682A/da
Publication of DK159688B publication Critical patent/DK159688B/da
Application granted granted Critical
Publication of DK159688C publication Critical patent/DK159688C/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/10—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a carbohydrate
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/082—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/62—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving uric acid

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Bakery Products And Manufacturing Methods Therefor (AREA)
  • Medicinal Preparation (AREA)
DK296682A 1981-07-07 1982-07-01 Oploeselig baerer-bundet lever-uricase, fremgangsmaade til dens fremstilling og anvendelse DK159688C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19813126759 DE3126759A1 (de) 1981-07-07 1981-07-07 Loesliche leber-uricase, verfahren zu ihrer herstellung und verwendung
DE3126759 1981-07-07

Publications (3)

Publication Number Publication Date
DK296682A true DK296682A (da) 1983-01-08
DK159688B DK159688B (da) 1990-11-19
DK159688C DK159688C (da) 1991-04-15

Family

ID=6136304

Family Applications (1)

Application Number Title Priority Date Filing Date
DK296682A DK159688C (da) 1981-07-07 1982-07-01 Oploeselig baerer-bundet lever-uricase, fremgangsmaade til dens fremstilling og anvendelse

Country Status (7)

Country Link
US (1) US4460683A (da)
EP (1) EP0069379B1 (da)
JP (1) JPS5841836B2 (da)
AT (1) ATE27967T1 (da)
DE (2) DE3126759A1 (da)
DK (1) DK159688C (da)
IE (1) IE53578B1 (da)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3515586A1 (de) * 1985-04-30 1986-11-06 Boehringer Mannheim Gmbh, 6800 Mannheim Stabilisiertes sarcosinoxidase-praeparat
DE3541186A1 (de) * 1985-11-21 1987-05-27 Boehringer Mannheim Gmbh Wasserloesliche, stabilisierte peroxidasederivate, verfahren zu ihrer herstellung und verwendung zur bestimmung von wasserstoffperoxid
JPH0648982B2 (ja) * 1986-10-06 1994-06-29 株式会社日立製作所 アミラーゼの分離精製方法およびそれに用いる吸着剤およびその分離精製装置
JPS6467186A (en) * 1987-09-04 1989-03-13 Kanebo Ltd Modified superoxide dismutase
EP0320483B1 (en) * 1987-12-11 1994-04-06 Monsanto Company Encapsulation method
JPH0269180A (ja) * 1988-09-02 1990-03-08 Daicel Chem Ind Ltd 高分子化酵素及びその製造方法
DE4011084A1 (de) * 1990-04-05 1991-10-10 Boehringer Mannheim Gmbh Saccharid-modifizierte, wasserloesliche proteine
FR2733914B1 (fr) * 1995-05-11 1997-08-01 Sanofi Sa Composition de liquide stable contenant de l'urate oxydase et composition lyophilisee pour sa preparation
US6541606B2 (en) 1997-12-31 2003-04-01 Altus Biologics Inc. Stabilized protein crystals formulations containing them and methods of making them
US6451572B1 (en) 1998-06-25 2002-09-17 Cornell Research Foundation, Inc. Overexpression of phytase genes in yeast systems
EP1100880B1 (en) 1998-08-06 2010-10-06 Duke University Urate oxidase
ES2404074T3 (es) 1998-08-06 2013-05-23 Mountain View Pharmaceuticals, Inc. Conjugados de peg-oxidasa de urato y su uso
US20060188971A1 (en) * 1998-08-06 2006-08-24 Duke University Urate oxidase
US6783965B1 (en) 2000-02-10 2004-08-31 Mountain View Pharmaceuticals, Inc. Aggregate-free urate oxidase for preparation of non-immunogenic polymer conjugates
AU4056700A (en) 1999-03-31 2000-10-16 Cornell Research Foundation Inc. Phosphatases with improved phytase activity
US6841370B1 (en) 1999-11-18 2005-01-11 Cornell Research Foundation, Inc. Site-directed mutagenesis of Escherichia coli phytase
US6913915B2 (en) * 2001-08-02 2005-07-05 Phoenix Pharmacologics, Inc. PEG-modified uricase
CA2465202C (en) * 2001-10-31 2014-01-21 Phytex, Llc Phytase-containing animal food and method
ATE492631T1 (de) * 2002-09-13 2011-01-15 Cornell Res Foundation Inc Verwendung von mutationen zur verbesserung von aspergillus-phytasen
PL3321359T3 (pl) 2005-04-11 2021-06-28 Horizon Pharma Rheumatology Llc Wariantowe postacie oksydazy moczanowej i ich zastosowanie
US20080159976A1 (en) * 2005-04-11 2008-07-03 Jacob Hartman Methods for lowering elevated uric acid levels using intravenous injections of PEG-uricase
US8148123B2 (en) * 2005-04-11 2012-04-03 Savient Pharmaceuticals, Inc. Methods for lowering elevated uric acid levels using intravenous injections of PEG-uricase
MX2007012548A (es) * 2005-04-11 2008-03-11 Savient Pharmaceuticals Inc Formas variantes de urato oxidasa y uso de las mismas.
EP1883425A1 (en) * 2005-05-23 2008-02-06 Universite De Geneve Injectable superparamagnetic nanoparticles for treatment by hyperthermia and use for forming an hyperthermic implant
US7919297B2 (en) 2006-02-21 2011-04-05 Cornell Research Foundation, Inc. Mutants of Aspergillus niger PhyA phytase and Aspergillus fumigatus phytase
HU230758B1 (hu) * 2006-04-12 2018-03-28 Crealta Pharmaceuticals LLC 100% Fehérjék tisztítása kationos felületaktív anyaggal
WO2008017066A2 (en) * 2006-08-03 2008-02-07 Cornell Research Foundation, Inc. Phytases with improved thermal stability
US8192734B2 (en) 2007-07-09 2012-06-05 Cornell University Compositions and methods for bone strengthening
US20110171268A1 (en) * 2008-03-24 2011-07-14 Althea Technologies, Inc. Uricase compositions and methods of use
EP3482768A1 (en) 2009-06-25 2019-05-15 Horizon Pharma Rheumatology LLC Methods and kits for predicting infusion reaction risk and antibody-mediated loss of response by monitoring serum uric acid during pegylated uricase therapy
CN115011586B (zh) * 2022-07-22 2024-07-23 江苏恰瑞生物科技有限公司 一种提高固定化尿酸酶酶活力的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3625827A (en) * 1968-09-27 1971-12-07 Monsanto Co Water-soluble polymer-enzyme products
JPS6031472B2 (ja) * 1978-12-14 1985-07-22 協和醗酵工業株式会社 酸性ウリカ−ゼ
JPS55135590A (en) * 1979-04-05 1980-10-22 Mihama Hisaharu Modified asparaginase and uricase and their preparation

Also Published As

Publication number Publication date
US4460683A (en) 1984-07-17
JPS5841836B2 (ja) 1983-09-14
DK159688B (da) 1990-11-19
DE3126759A1 (de) 1983-01-27
EP0069379A3 (en) 1984-10-17
DE3276637D1 (en) 1987-07-30
EP0069379A2 (de) 1983-01-12
JPS5816680A (ja) 1983-01-31
DK159688C (da) 1991-04-15
EP0069379B1 (de) 1987-06-24
ATE27967T1 (de) 1987-07-15
IE821510L (en) 1983-01-07
IE53578B1 (en) 1988-12-21

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