DK294589A - Nukleinsyremultimerer og forstaerkede nukleinsyrehybridiseringsanalyser omfattende samme - Google Patents

Nukleinsyremultimerer og forstaerkede nukleinsyrehybridiseringsanalyser omfattende samme Download PDF

Info

Publication number
DK294589A
DK294589A DK294589A DK294589A DK294589A DK 294589 A DK294589 A DK 294589A DK 294589 A DK294589 A DK 294589A DK 294589 A DK294589 A DK 294589A DK 294589 A DK294589 A DK 294589A
Authority
DK
Denmark
Prior art keywords
nucleic acid
multimates
hybridization analysis
oligonucleotide
acid hybridization
Prior art date
Application number
DK294589A
Other languages
English (en)
Other versions
DK294589D0 (da
DK175932B1 (da
Inventor
Michael S Urdea
Brian Warner
Joyce A Running
Janice A Kolberg
Jennifer M Clyne
Ray Sanchez-Pescador
Thomas Horn
Original Assignee
Chiron Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiron Corp filed Critical Chiron Corp
Publication of DK294589D0 publication Critical patent/DK294589D0/da
Publication of DK294589A publication Critical patent/DK294589A/da
Application granted granted Critical
Publication of DK175932B1 publication Critical patent/DK175932B1/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06Pyrimidine radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
    • C12Q1/682Signal amplification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701Specific hybridization probes
    • C12Q1/706Specific hybridization probes for hepatitis
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531Production of immunochemical test materials
    • G01N33/532Production of labelled immunochemicals
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/01DNA viruses
    • G01N2333/03Herpetoviridae, e.g. pseudorabies virus
    • G01N2333/04Varicella-zoster virus
    • G01N2333/045Cytomegalovirus
DK198902945A 1987-10-15 1989-06-15 Syntetiske forgrenede nukleinsyremultimerer og fremgangsmåder til at udföre nukleinsyrehybridiseringsanalyser omfattende samme, anvendelse af samme som komponent i en sådan analyse og en fremgangsmåde til art udföre en immunanalyse DK175932B1 (da)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US10928287A 1987-10-15 1987-10-15
US10928287 1987-10-15
US18520188A 1988-04-22 1988-04-22
US18520188 1988-04-22
US25263888A 1988-09-30 1988-09-30
US25263888 1988-09-30
US8803644 1988-10-14
PCT/US1988/003644 WO1989003891A1 (en) 1987-10-15 1988-10-14 Nucleic acid multimers and amplified nucleic acid hybridization assays using same

Publications (3)

Publication Number Publication Date
DK294589D0 DK294589D0 (da) 1989-06-15
DK294589A true DK294589A (da) 1989-08-15
DK175932B1 DK175932B1 (da) 2005-07-18

Family

ID=27380635

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198902945A DK175932B1 (da) 1987-10-15 1989-06-15 Syntetiske forgrenede nukleinsyremultimerer og fremgangsmåder til at udföre nukleinsyrehybridiseringsanalyser omfattende samme, anvendelse af samme som komponent i en sådan analyse og en fremgangsmåde til art udföre en immunanalyse

Country Status (9)

Country Link
EP (1) EP0317077B1 (da)
AT (1) ATE133713T1 (da)
CA (1) CA1339351C (da)
DE (1) DE3854956T2 (da)
DK (1) DK175932B1 (da)
ES (1) ES2083363T3 (da)
GR (1) GR3019046T3 (da)
IE (1) IE75211B1 (da)
WO (1) WO1989003891A1 (da)

Families Citing this family (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5118605A (en) * 1984-10-16 1992-06-02 Chiron Corporation Polynucleotide determination with selectable cleavage sites
US5430136A (en) * 1984-10-16 1995-07-04 Chiron Corporation Oligonucleotides having selectably cleavable and/or abasic sites
US5175270A (en) * 1986-09-10 1992-12-29 Polyprobe, Inc. Reagents for detecting and assaying nucleic acid sequences
US5124246A (en) * 1987-10-15 1992-06-23 Chiron Corporation Nucleic acid multimers and amplified nucleic acid hybridization assays using same
US5359100A (en) * 1987-10-15 1994-10-25 Chiron Corporation Bifunctional blocked phosphoramidites useful in making nucleic acid mutimers
US5656731A (en) * 1987-10-15 1997-08-12 Chiron Corporation Nucleic acid-amplified immunoassay probes
US5350671A (en) * 1987-11-18 1994-09-27 Chiron Corporation HCV immunoassays employing C domain antigens
US5047523A (en) * 1988-08-02 1991-09-10 Ortho Diagnostic Systems Inc. Nucleic acid probe for detection of neisseria gonorrhoea
EP0447464B1 (en) * 1988-12-09 1998-08-05 Amrad Corporation Limited Amplified dna assay
DE3925613A1 (de) * 1989-06-22 1991-01-03 Boehringer Mannheim Gmbh Neisseria-spezifische dna-sonde
JP3156200B2 (ja) 1989-09-15 2001-04-16 国立予防衛生研究所長 新規のhcv分離株
US5232829A (en) * 1989-09-29 1993-08-03 Hoffmann-La Roche Inc. Detection of chlamydia trachomatis by polymerase chain reaction using biotin labelled lina primers and capture probes
CA2025179A1 (en) * 1989-10-12 1991-04-13 William G. Weisburg Nucleic acid probes and methods for detecting cryptococcus neoformans
CA2025180A1 (en) * 1989-10-12 1991-04-13 William G. Weisburg Nucleic acid probes and methods for detecting pathogenic candida yeasts
GB8924989D0 (en) * 1989-11-06 1989-12-28 Scotgen Ltd Method and device for the detection of antibiotic resistance
US5629153A (en) * 1990-01-10 1997-05-13 Chiron Corporation Use of DNA-dependent RNA polymerase transcripts as reporter molecules for signal amplification in nucleic acid hybridization assays
WO1991010746A1 (en) 1990-01-10 1991-07-25 Chiron Corporation Dna-dependent rna polymerase transcripts as reporter molecules for signal amplification in nucleic acid hybridization assays
CA2037349C (en) * 1990-03-26 2008-06-17 James G. Wetmur Branch migration of nucleotides
CA2039517C (en) * 1990-04-03 2006-11-07 David Segev Dna probe signal amplification
HUT64623A (en) * 1990-05-04 1994-01-28 Chiron Corp Protein and nucleinic acid samples and immunic essays containing them
US5430138A (en) * 1990-07-27 1995-07-04 Chiron Corporation Hydroxyl-protecting groups attached to cytidine nucleotide compounds which are orthogonally removable
US5849481A (en) * 1990-07-27 1998-12-15 Chiron Corporation Nucleic acid hybridization assays employing large comb-type branched polynucleotides
EP0541693B1 (en) * 1990-07-27 1998-12-09 Chiron Corporation Large comb-type branched polynucleotides
US5420330A (en) * 1990-09-07 1995-05-30 Pharmacia P-L Biochemicals Inc. Lipo-phosphoramidites
KR940701454A (ko) * 1991-06-17 1994-05-28 로버트 피. 블랙버언 선택가능한 절단부위로의 폴리뉴클레오티드의 결정
US5747244A (en) * 1991-12-23 1998-05-05 Chiron Corporation Nucleic acid probes immobilized on polystyrene surfaces
CA2124795A1 (en) * 1991-12-23 1993-07-08 Ray Sanchez-Pescador Chlamydiae probes for use in solution phase sandwich hybridization assays
ATE199158T1 (de) * 1991-12-23 2001-02-15 Bayer Ag Hbv amplifizierungssonden zur verwendung in hybridisierungssandwichassay in der lösungsphase
EP0672174A4 (en) * 1991-12-23 1997-07-16 Chiron Corp HTLV-1 SAMPLES FOR USE OF SANDWICH HYBRIDIZATION METHODS SOLUTION.
JPH07502655A (ja) * 1991-12-23 1995-03-23 バイエル コーポレイション 溶液相サンドイッチハイブリダイゼーションアッセイに用いるためのcmvプローブ
JPH07502658A (ja) * 1991-12-23 1995-03-23 バイエル コーポレイション 溶液相サンドイッチハイブリダイゼーションアッセイに用いるためのhavプローブ
EP0726962B1 (en) * 1991-12-23 2006-06-07 Chiron Corporation Sets of HIV probes for use in solution phase sandwich hybridisation assays
AU4596893A (en) * 1992-05-29 1993-12-30 Gen Trak, Inc. Signal amplification probe and methods of use
US5985548A (en) * 1993-02-04 1999-11-16 E. I. Du Pont De Nemours And Company Amplification of assay reporters by nucleic acid replication
BE1007918A3 (fr) * 1993-02-19 1995-11-21 Wallone Region Sondes d'acides nucleiques chimiquement modifiees en 5'(oh) et/ou en 3'(oh) en vue de l'introduction en ces positions d'un ou plusieurs elements de marquage non radioactif et procede de preparation.
FR2710075B1 (fr) * 1993-09-15 1995-10-27 Bio Merieux Réactif et procédé pour la détection d'une séquence nucléotidique avec amplification de signal.
US5561043A (en) * 1994-01-31 1996-10-01 Trustees Of Boston University Self-assembling multimeric nucleic acid constructs
US5648213A (en) * 1994-08-30 1997-07-15 Beckman Instruments, Inc. Compositions and methods for use in detection of analytes
US5853974A (en) 1995-06-07 1998-12-29 Chiron Corporation Enhancement of alkaline phosphatase with SDS in chemiluminescent substrates
US5780227A (en) * 1995-06-07 1998-07-14 Sheridan; Patrick J. Oligonucleotide probe conjugated to a purified hydrophilic alkaline phosphatase and uses thereof
US6632936B2 (en) 1995-09-06 2003-10-14 Icos Corp Cell-cycle checkpoint genes
CA2218440A1 (en) * 1996-12-21 1998-06-21 Boehringer Mannheim Gmbh Method of analysis using signal amplification
WO1999020752A1 (en) 1997-10-21 1999-04-29 The University Court Of The University Of Glasgow JMY, A CO-ACTIVATOR FOR p300/CBP, NUCLEIC ACID ENCODING JMY AND USES THEREOF
US5962273A (en) * 1997-11-04 1999-10-05 Becton Dickinson And Company Detection of Neisseria gonorrhoeae by amplification and detection of its nucleic acid
GB9806093D0 (en) 1998-03-20 1998-05-20 Taylor John Hermon Diagnostics and vaccines for mycobacterial infections of animals and humans
US5976805A (en) * 1998-04-27 1999-11-02 Becton Dickinson And Company Neisseria gonorrhoeae specific DNA fragment--GC3
US6468743B1 (en) * 1998-05-18 2002-10-22 Conagra Grocery Products Company PCR techniques for detecting microbial contaminants in foodstuffs
GB9811403D0 (en) * 1998-05-27 1998-07-22 Isis Innovation Polynucleotide multimers and their use in hybridisation assays
US6203989B1 (en) 1998-09-30 2001-03-20 Affymetrix, Inc. Methods and compositions for amplifying detectable signals in specific binding assays
GB9914943D0 (en) * 1999-06-25 1999-08-25 Imp College Innovations Ltd Methods
CA2403911A1 (en) * 2000-03-29 2001-10-04 Polyprobe, Inc. Quality control reagents for nucleic acid microarrays
US7763421B2 (en) 2000-06-05 2010-07-27 Ventana Medical Systems, Inc. Methods for producing nucleic acid hybridization probes that amplify hybridization signal by promoting network formation
JP2004524010A (ja) 2000-11-30 2004-08-12 モルキューラー スキンケア リミテッド 疾患の診断および処置
WO2004058159A2 (en) 2002-12-23 2004-07-15 Dynavax Technologies Corporation Branched immunomodulatory compounds and methods of using the same
US7229800B2 (en) 2004-04-16 2007-06-12 Becton, Dickinson And Company Neisseria gonorrhoeae assay
AU2007235282A1 (en) * 2006-04-07 2007-10-18 Siemens Healthcare Diagnostics Inc. Neisseria gonorrhoeae specific oligonucleotide sequences
JP2008043332A (ja) * 2006-08-17 2008-02-28 Panomics Inc 組織スライドからの核酸定量
EP2116618A1 (en) 2008-05-09 2009-11-11 Agency for Science, Technology And Research Diagnosis and treatment of Kawasaki disease
EP2291545B1 (en) 2008-06-14 2013-05-08 Veredus Laboratories Pte Ltd Influenza sequences
WO2010071610A1 (en) 2008-12-19 2010-06-24 Agency For Science, Technology And Research (A*Star) Severe chikungunya biomarkers

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI71768C (fi) * 1984-02-17 1987-02-09 Orion Yhtymae Oy Foerbaettrade nykleinsyrareagenser och foerfarande foer deras framstaellning.
GB8405437D0 (en) * 1984-03-01 1984-04-04 Amersham Int Plc Detecting polynucleotide sequences
DE3420925A1 (de) * 1984-06-05 1985-12-05 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren und reagenz zum nachweis einer nukleinsaeure-sequenz
US4755458A (en) * 1984-08-30 1988-07-05 Enzo Biochem, Inc. Composition and method for the detection of the presence of a polynucleotide sequence of interest
US4883750A (en) * 1984-12-13 1989-11-28 Applied Biosystems, Inc. Detection of specific sequences in nucleic acids
CA1272443A (en) * 1985-02-22 1990-08-07 Nanibhushan Dattagupta Solution-phase dual hybridization assay for detecting polynucleotide sequences
US5252760A (en) 1985-03-28 1993-10-12 Chiron Corporation Method of using colored phosphorylating reagents
ATE65092T1 (de) * 1985-05-31 1991-07-15 Amoco Corp Verstaerkung von hybridisierungssignalen durch verwendung von komplementarischen dns-straengen.
US4868105A (en) * 1985-12-11 1989-09-19 Chiron Corporation Solution phase nucleic acid sandwich assay
US4882269A (en) * 1985-12-13 1989-11-21 Princeton University Amplified hybridization assay
EP0238332A2 (en) * 1986-03-19 1987-09-23 Cetus Corporation Liquid hybridization method and kit for detecting the presence of nucleic acid sequences in samples

Also Published As

Publication number Publication date
DE3854956T2 (de) 1996-06-13
IE883131L (en) 1989-04-15
DE3854956D1 (de) 1996-03-14
DK294589D0 (da) 1989-06-15
ES2083363T3 (es) 1996-04-16
CA1339351C (en) 1997-08-26
WO1989003891A1 (en) 1989-05-05
EP0317077A1 (en) 1989-05-14
DK175932B1 (da) 2005-07-18
IE75211B1 (en) 1997-08-27
EP0317077B1 (en) 1996-01-31
GR3019046T3 (en) 1996-05-31
ATE133713T1 (de) 1996-02-15

Similar Documents

Publication Publication Date Title
DK294589A (da) Nukleinsyremultimerer og forstaerkede nukleinsyrehybridiseringsanalyser omfattende samme
DE69027211D1 (de) Verbesserte nukleinsäure-hybridisierungstests für hbv, die amplifikation verwenden
ZA902190B (en) Process for insolating nucleic acid
DE69233630D1 (de) Sätze von HIV Sonden für Solution Sandwich Hybridationsverfahren
DK0567635T3 (da) Hurtige assays for amplifikationsprodukter
ATE115959T1 (de) Markiertes dna.
DK0543942T3 (da) Homogent assaysystem
IS3350A7 (is) Efnabætt næringarefni og aðferð til framleiðslu þess ( efnabætt með nucleosides og/eða nucleotides)
ATE199158T1 (de) Hbv amplifizierungssonden zur verwendung in hybridisierungssandwichassay in der lösungsphase
DE69334050D1 (de) Nukleinsäure-Sonden für Chlamydia Pneumoniae
DE69328951D1 (de) Nukleinsäuresonden für Mykobacterium Tuberkulosis
NO882593D0 (no) Forbedret nykleinsyrehybridiseringsteknikk og kit til dette.
DE3787521T2 (de) Photodetektionssystem für die DNA-Basen-Analyse.
KR940012633U (ko) 핵산(dna) 증폭 배양기
NO875058L (no) Oligonukleotidprober og fremgangsmÿte for detektering av nukleinsyrene i bakterier og andre levende organismer ved hybridisering.
ATE80667T1 (de) T7-dns-polymerase.