DK2931728T3 - Chlorinderivat, der er nyttigt ved fotodynamisk terapi og diagnose - Google Patents

Chlorinderivat, der er nyttigt ved fotodynamisk terapi og diagnose Download PDF

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Publication number
DK2931728T3
DK2931728T3 DK13821500.9T DK13821500T DK2931728T3 DK 2931728 T3 DK2931728 T3 DK 2931728T3 DK 13821500 T DK13821500 T DK 13821500T DK 2931728 T3 DK2931728 T3 DK 2931728T3
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DK
Denmark
Prior art keywords
diagnosis
photodynamic therapy
derivative used
chlorine derivative
chlorine
Prior art date
Application number
DK13821500.9T
Other languages
English (en)
Inventor
Honsue Cho
Original Assignee
Rmw Cho Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB1222544.7A external-priority patent/GB201222544D0/en
Priority claimed from GB1309337.2A external-priority patent/GB2514408A/en
Application filed by Rmw Cho Group Ltd filed Critical Rmw Cho Group Ltd
Application granted granted Critical
Publication of DK2931728T3 publication Critical patent/DK2931728T3/da

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0071PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/001Preparation for luminescence or biological staining
    • A61K49/0013Luminescence
    • A61K49/0017Fluorescence in vivo
    • A61K49/0019Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0036Porphyrins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/10Anti-acne agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • A61P31/22Antivirals for DNA viruses for herpes viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biochemistry (AREA)
  • Cardiology (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • AIDS & HIV (AREA)
  • Endocrinology (AREA)
  • Pulmonology (AREA)
  • Biotechnology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Gastroenterology & Hepatology (AREA)
DK13821500.9T 2012-12-14 2013-12-13 Chlorinderivat, der er nyttigt ved fotodynamisk terapi og diagnose DK2931728T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1222544.7A GB201222544D0 (en) 2012-12-14 2012-12-14 Photodynamic therapy and diagnosis
GB1309337.2A GB2514408A (en) 2013-05-23 2013-05-23 Photodynamic Therapy and Diagnosis
PCT/GB2013/053285 WO2014091241A1 (en) 2012-12-14 2013-12-13 Chlorin derivative useful in photodynamic therapy and diagnosis

Publications (1)

Publication Number Publication Date
DK2931728T3 true DK2931728T3 (da) 2020-05-11

Family

ID=49958497

Family Applications (1)

Application Number Title Priority Date Filing Date
DK13821500.9T DK2931728T3 (da) 2012-12-14 2013-12-13 Chlorinderivat, der er nyttigt ved fotodynamisk terapi og diagnose

Country Status (24)

Country Link
US (1) US20150315202A1 (da)
EP (1) EP2931728B1 (da)
JP (1) JP6396919B2 (da)
KR (1) KR102242404B1 (da)
CN (2) CN105008372B (da)
AU (2) AU2013357030B2 (da)
CA (1) CA2894968C (da)
CY (1) CY1122834T1 (da)
DK (1) DK2931728T3 (da)
ES (1) ES2791004T3 (da)
HK (1) HK1216534A1 (da)
HR (1) HRP20200734T1 (da)
HU (1) HUE048861T2 (da)
IL (1) IL239347B (da)
LT (1) LT2931728T (da)
ME (1) ME03725B (da)
MY (1) MY180320A (da)
PH (1) PH12015501341B1 (da)
PL (1) PL2931728T3 (da)
PT (1) PT2931728T (da)
RS (1) RS60225B1 (da)
SG (1) SG11201504595UA (da)
SI (1) SI2931728T1 (da)
WO (1) WO2014091241A1 (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3331488A4 (en) 2015-08-08 2019-04-17 CHL Industries, LLC IMPROVED HYALURONANE AND MODIFIED HYALURONAN IN BIOMEDICAL APPLICATIONS
RU2753402C1 (ru) * 2020-04-15 2021-08-16 Федеральное государтвенное бюджетное учреждение "Российский научный центр радиологии и хирургических технологий имени академика А.М. Гранова" Министерства здравоохранения Российской Федерации Способ фотодинамической терапии при лечении нерезекабельной аденокарциномы внепеченочных желчных протоков
GB202018667D0 (en) * 2020-11-26 2021-01-13 Rmw Cho Group Ltd Photodynamic therapy and diagnosis
CN113527319B (zh) * 2021-06-10 2023-03-07 中国人民解放军海军军医大学 一种新型二氢卟吩e4衍生物及其药学上可接受的盐和制备方法与应用
WO2024115524A1 (en) 2022-11-28 2024-06-06 Rmw Cho Group Limited Porphyrin and phosphonium-porphyrin based compounds for photodynamic therapy and diagnostics
GB202217863D0 (en) 2022-11-28 2023-01-11 Rmw Cho Group Ltd Novel compounds
WO2024115525A2 (en) 2022-11-28 2024-06-06 Rmw Cho Group Limited Novel compounds
GB202217864D0 (en) 2022-11-28 2023-01-11 Rmw Cho Group Ltd Novel compounds

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5002962A (en) * 1988-07-20 1991-03-26 Health Research, Inc. Photosensitizing agents
JP2963178B2 (ja) * 1990-09-27 1999-10-12 株式会社エス・エル・ティ・ジャパン 水溶性フェオホーバイドaの製造方法
CN1148184C (zh) * 1999-10-28 2004-05-05 上海复旦张江生物医药股份有限公司 光动力治疗肿瘤药物组合物
RU2183956C1 (ru) * 2001-03-30 2002-06-27 Общество с ограниченной ответственностью "РАДА-ФАРМА" Фотосенсибилизатор и способ его получения
CA2462261A1 (en) * 2001-10-03 2003-04-10 Miravant Pharmaceuticals, Inc. Chlorin photosensitizing agents for use in photodynamic therapy
CN100443485C (zh) * 2005-04-08 2008-12-17 吴华君 叶绿酸合铁钠盐衍生物、制备方法及用途
GB0718878D0 (en) * 2007-09-28 2007-11-07 Photo Diagnostic Devices Pdd L Photodynamic Theraphy and diagnosis

Also Published As

Publication number Publication date
SG11201504595UA (en) 2015-07-30
AU2013357030A8 (en) 2015-07-16
RS60225B1 (sr) 2020-06-30
AU2013357030A1 (en) 2014-06-19
PT2931728T (pt) 2020-04-29
CN105008372A (zh) 2015-10-28
CN110003225A (zh) 2019-07-12
CN105008372B (zh) 2020-01-17
JP6396919B2 (ja) 2018-09-26
LT2931728T (lt) 2020-06-10
AU2013357030B2 (en) 2018-03-29
AU2018282411A1 (en) 2019-01-17
HK1216534A1 (zh) 2016-11-18
ES2791004T3 (es) 2020-10-30
KR20150096432A (ko) 2015-08-24
CA2894968C (en) 2023-02-14
US20150315202A1 (en) 2015-11-05
IL239347B (en) 2018-07-31
EP2931728B1 (en) 2020-02-19
PH12015501341A1 (en) 2015-09-07
IL239347A0 (en) 2015-07-30
JP2016502999A (ja) 2016-02-01
CA2894968A1 (en) 2014-06-19
ME03725B (me) 2021-01-20
KR102242404B1 (ko) 2021-04-21
PL2931728T3 (pl) 2020-11-02
PH12015501341B1 (en) 2015-09-07
HUE048861T2 (hu) 2020-08-28
MY180320A (en) 2020-11-28
SI2931728T1 (sl) 2020-08-31
EP2931728A1 (en) 2015-10-21
CY1122834T1 (el) 2021-05-05
WO2014091241A1 (en) 2014-06-19
HRP20200734T1 (hr) 2020-09-18

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