DK2912186T3 - Behandling rettet mod blodplader - Google Patents
Behandling rettet mod blodplader Download PDFInfo
- Publication number
- DK2912186T3 DK2912186T3 DK13848463.9T DK13848463T DK2912186T3 DK 2912186 T3 DK2912186 T3 DK 2912186T3 DK 13848463 T DK13848463 T DK 13848463T DK 2912186 T3 DK2912186 T3 DK 2912186T3
- Authority
- DK
- Denmark
- Prior art keywords
- blood plates
- treatment targeted
- targeted
- treatment
- blood
- Prior art date
Links
- 239000008280 blood Substances 0.000 title 1
- 210000004369 blood Anatomy 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70546—Integrin superfamily
- C07K14/7055—Integrin beta1-subunit-containing molecules, e.g. CD29, CD49
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
- A61K48/0058—Nucleic acids adapted for tissue specific expression, e.g. having tissue specific promoters as part of a contruct
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- Biophysics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Hematology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Toxicology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Developmental Biology & Embryology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Virology (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261717951P | 2012-10-24 | 2012-10-24 | |
| PCT/US2013/066651 WO2014066663A1 (en) | 2012-10-24 | 2013-10-24 | Platelet targeted treatment |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2912186T3 true DK2912186T3 (da) | 2021-02-22 |
Family
ID=50545271
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK13848463.9T DK2912186T3 (da) | 2012-10-24 | 2013-10-24 | Behandling rettet mod blodplader |
Country Status (12)
| Country | Link |
|---|---|
| US (4) | US9982034B2 (enExample) |
| EP (2) | EP2912186B1 (enExample) |
| JP (2) | JP2016501515A (enExample) |
| KR (1) | KR101819803B1 (enExample) |
| BR (1) | BR112015009229B1 (enExample) |
| CA (1) | CA2888982C (enExample) |
| DK (1) | DK2912186T3 (enExample) |
| ES (1) | ES2854754T3 (enExample) |
| IL (1) | IL238417B (enExample) |
| PL (1) | PL2912186T3 (enExample) |
| WO (1) | WO2014066663A1 (enExample) |
| ZA (1) | ZA201502945B (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11319528B2 (en) | 2015-07-13 | 2022-05-03 | University Of Utah Research Foundation | Methods of making red blood cells and platelets in vitro and uses thereof |
| KR102592176B1 (ko) | 2018-01-05 | 2023-10-20 | 플레이틀렛 바이오제네시스, 인크. | 거핵구 생성을 위한 조성물 및 방법 |
| JP2021529770A (ja) | 2018-06-29 | 2021-11-04 | プレートレット バイオジェネシス， インコーポレイテッド | 薬物送達のための組成物およびその使用方法 |
| US20220033776A1 (en) * | 2018-10-05 | 2022-02-03 | University Of Utah Research Foundation | Methods of making platelets comprising modified receptors and uses thereof |
| EP3887402A4 (en) | 2018-11-30 | 2022-10-26 | Cellphire, Inc. | PLATELETS AS RELEASING AGENT |
| WO2020112963A1 (en) | 2018-11-30 | 2020-06-04 | Cellphire, Inc. | Platelets as delivery agents |
| EP3937631A4 (en) * | 2019-03-13 | 2023-01-04 | Cellphire Inc. | DOG PLALETLET PREPARATIONS |
| CN114072159A (zh) | 2019-05-03 | 2022-02-18 | 塞尔菲乐有限公司 | 用于生产血液产品的材料和方法 |
| CN114450066A (zh) | 2019-08-16 | 2022-05-06 | 塞尔菲乐有限公司 | 作为抗血小板剂逆转剂的血栓小体 |
| CA3170196A1 (en) | 2020-02-04 | 2021-08-12 | Cellphire, Inc. | Anti-fibrinolytic loaded platelets |
| DE102020111571A1 (de) | 2020-03-11 | 2021-09-16 | Immatics US, Inc. | Wpre-mutantenkonstrukte, zusammensetzungen und zugehörige verfahren |
| TW202245814A (zh) | 2021-02-17 | 2022-12-01 | 美商賽菲爾公司 | 用於治療抗血小板誘導的凝血病之凍乾血小板衍生物組成物 |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2452892A (en) | 1947-05-07 | 1948-11-02 | Robert A Appleton | Igniter for rockets |
| US4596556A (en) | 1985-03-25 | 1986-06-24 | Bioject, Inc. | Hypodermic injection apparatus |
| EP0468520A3 (en) | 1990-07-27 | 1992-07-01 | Mitsui Toatsu Chemicals, Inc. | Immunostimulatory remedies containing palindromic dna sequences |
| IL101715A (en) | 1991-05-02 | 2005-06-19 | Amgen Inc | Recombinant dna-derived cholera toxin subunit analogs |
| IT1253009B (it) | 1991-12-31 | 1995-07-10 | Sclavo Ricerca S R L | Mutanti immunogenici detossificati della tossina colerica e della tossina lt, loro preparazione ed uso per la preparazione di vaccini |
| PT761231E (pt) | 1992-06-25 | 2000-06-30 | Smithkline Beecham Biolog | Composicao de vacina contendo adjuvantes |
| GB9326253D0 (en) | 1993-12-23 | 1994-02-23 | Smithkline Beecham Biolog | Vaccines |
| ES2366201T3 (es) | 1994-07-15 | 2011-10-18 | University Of Iowa Research Foundation | Oligonucleótidos inmunmoduladores. |
| UA56132C2 (uk) | 1995-04-25 | 2003-05-15 | Смітклайн Бічем Байолоджікалс С.А. | Композиція вакцини (варіанти), спосіб стабілізації qs21 відносно гідролізу (варіанти), спосіб приготування композиції вакцини |
| ZA975326B (en) | 1996-06-18 | 1998-01-14 | Alza Corp | Device and method for enhancing transdermal flux of agents being delivered or sampled. |
| US5980898A (en) | 1996-11-14 | 1999-11-09 | The United States Of America As Represented By The U.S. Army Medical Research & Material Command | Adjuvant for transcutaneous immunization |
| WO1998028037A1 (en) | 1996-12-20 | 1998-07-02 | Alza Corporation | Device and method for enhancing transdermal agent flux |
| US5993412A (en) | 1997-05-19 | 1999-11-30 | Bioject, Inc. | Injection apparatus |
| GB9711990D0 (en) | 1997-06-11 | 1997-08-06 | Smithkline Beecham Biolog | Vaccine |
| JP4426091B2 (ja) | 1997-09-05 | 2010-03-03 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | サポニンを含有する水中油型エマルション |
| GB9718901D0 (en) | 1997-09-05 | 1997-11-12 | Smithkline Beecham Biolog | Vaccine |
| EP1035867A1 (en) | 1997-12-02 | 2000-09-20 | Powderject Vaccines, Inc. | Transdermal delivery of particulate vaccine compositions |
| EP1048736A1 (en) * | 1999-04-27 | 2000-11-02 | Aventis Behring Gesellschaft mit beschränkter Haftung | DNA-construct for the tissue specific expression of a blood coagulation factor |
| EP1397496A2 (en) * | 2001-06-15 | 2004-03-17 | Andre Schuh | Gene therapy for hemophilia a |
| EP1412493B1 (en) * | 2001-08-02 | 2011-10-05 | Institut Clayton De La Recherche | Methods and compositions relating to improved lentiviral vector production systems |
| WO2003030934A2 (en) | 2001-10-06 | 2003-04-17 | Merial Limited | Cpg formulations and related methods |
| US7417026B2 (en) | 2003-08-13 | 2008-08-26 | Children's Hospital Medical Center | Mobilization of hematopoietic cells |
| JP2008518610A (ja) * | 2004-11-03 | 2008-06-05 | アルマック ダイアグノスティックス リミテッド | トランスクリプトームマイクロアレイ技法およびそれを使用する方法 |
| KR100981092B1 (ko) | 2008-02-29 | 2010-09-08 | 고려대학교 산학협력단 | 제8 혈액응고 인자와 폰 빌리 블란트 인자 변이체의 재조합발현 벡터 시스템 |
| WO2010075303A1 (en) | 2008-12-23 | 2010-07-01 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Splicing factors with a puf protein rna-binding domain and a splicing effector domain and uses of same |
| US8147820B2 (en) | 2009-09-14 | 2012-04-03 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Attenuated vaccine against fish pathogen Francisella sp |
| PT2499165T (pt) | 2009-11-13 | 2016-10-28 | Grifols Therapeutics Inc | Preparações que contêm o fator de von willebrand (vwf), e métodos, kits e utilizações relacionadas com as mesmas |
| US20120225028A1 (en) | 2011-03-02 | 2012-09-06 | Moshe Cohen | Compositions and methods for mobilization of stem cells |
-
2013
- 2013-10-24 KR KR1020157012821A patent/KR101819803B1/ko active Active
- 2013-10-24 CA CA2888982A patent/CA2888982C/en active Active
- 2013-10-24 BR BR112015009229-2A patent/BR112015009229B1/pt active IP Right Grant
- 2013-10-24 EP EP13848463.9A patent/EP2912186B1/en active Active
- 2013-10-24 JP JP2015539804A patent/JP2016501515A/ja active Pending
- 2013-10-24 WO PCT/US2013/066651 patent/WO2014066663A1/en not_active Ceased
- 2013-10-24 DK DK13848463.9T patent/DK2912186T3/da active
- 2013-10-24 PL PL13848463T patent/PL2912186T3/pl unknown
- 2013-10-24 ES ES13848463T patent/ES2854754T3/es active Active
- 2013-10-24 EP EP21150184.6A patent/EP3859004A1/en active Pending
- 2013-10-24 US US14/437,457 patent/US9982034B2/en active Active
-
2015
- 2015-04-21 IL IL238417A patent/IL238417B/en active IP Right Grant
- 2015-04-29 ZA ZA2015/02945A patent/ZA201502945B/en unknown
-
2017
- 2017-08-29 US US15/689,875 patent/US10294291B2/en active Active
-
2018
- 2018-07-19 JP JP2018135886A patent/JP6975105B2/ja active Active
-
2019
- 2019-03-22 US US16/361,591 patent/US20190270791A1/en not_active Abandoned
-
2023
- 2023-08-07 US US18/366,237 patent/US20240270822A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA2888982A1 (en) | 2014-05-01 |
| US20150344541A1 (en) | 2015-12-03 |
| PL2912186T3 (pl) | 2021-06-14 |
| BR112015009229B1 (pt) | 2021-07-20 |
| JP6975105B2 (ja) | 2021-12-01 |
| US20240270822A1 (en) | 2024-08-15 |
| IL238417A0 (en) | 2015-06-30 |
| HK1211986A1 (en) | 2016-06-03 |
| KR101819803B1 (ko) | 2018-01-17 |
| IL238417B (en) | 2019-07-31 |
| US9982034B2 (en) | 2018-05-29 |
| ES2854754T3 (es) | 2021-09-22 |
| BR112015009229A2 (pt) | 2017-11-14 |
| EP2912186A1 (en) | 2015-09-02 |
| US20190270791A1 (en) | 2019-09-05 |
| EP2912186B1 (en) | 2021-01-06 |
| WO2014066663A1 (en) | 2014-05-01 |
| KR20150069017A (ko) | 2015-06-22 |
| CA2888982C (en) | 2020-07-21 |
| JP2018161152A (ja) | 2018-10-18 |
| JP2016501515A (ja) | 2016-01-21 |
| US10294291B2 (en) | 2019-05-21 |
| EP2912186A4 (en) | 2016-06-08 |
| ZA201502945B (en) | 2016-11-30 |
| US20180009874A1 (en) | 2018-01-11 |
| EP3859004A1 (en) | 2021-08-04 |
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