DK2858490T5 - Recombinant DNA elements for expression of recombinant proteins in insects - Google Patents
Recombinant DNA elements for expression of recombinant proteins in insects Download PDFInfo
- Publication number
- DK2858490T5 DK2858490T5 DK12753914.6T DK12753914T DK2858490T5 DK 2858490 T5 DK2858490 T5 DK 2858490T5 DK 12753914 T DK12753914 T DK 12753914T DK 2858490 T5 DK2858490 T5 DK 2858490T5
- Authority
- DK
- Denmark
- Prior art keywords
- recombinant
- baculovirus
- insect
- ser
- nucleic acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/60—New or modified breeds of invertebrates
- A01K67/61—Genetically modified invertebrates, e.g. transgenic or polyploid
- A01K67/65—Genetically modified arthropods
- A01K67/68—Genetically modified insects
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
- C12N15/866—Baculoviral vectors
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/70—Invertebrates
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/70—Invertebrates
- A01K2227/706—Insects, e.g. Drosophila melanogaster, medfly
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/01—Animal expressing industrially exogenous proteins
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/02—Animal zootechnically ameliorated
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/14011—Baculoviridae
- C12N2710/14111—Nucleopolyhedrovirus, e.g. autographa californica nucleopolyhedrovirus
- C12N2710/14122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/14011—Baculoviridae
- C12N2710/14111—Nucleopolyhedrovirus, e.g. autographa californica nucleopolyhedrovirus
- C12N2710/14141—Use of virus, viral particle or viral elements as a vector
- C12N2710/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/001—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination
- C12N2830/002—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination inducible enhancer/promoter combination, e.g. hypoxia, iron, transcription factor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/60—Vector systems having a special element relevant for transcription from viruses
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Environmental Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Animal Behavior & Ethology (AREA)
- Plant Pathology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Animal Husbandry (AREA)
- Biodiversity & Conservation Biology (AREA)
- Virology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161495467P | 2011-06-10 | 2011-06-10 | |
| EP11169634 | 2011-06-10 | ||
| EP2011068381 | 2011-10-20 | ||
| EP2011072406 | 2011-12-12 | ||
| PCT/EP2012/061088 WO2012168493A2 (en) | 2011-06-10 | 2012-06-12 | Recombinant dna elements for the expression of recombinant proteins in insects |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK2858490T3 DK2858490T3 (en) | 2016-12-12 |
| DK2858490T5 true DK2858490T5 (en) | 2017-01-23 |
Family
ID=47296540
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK12753914.6T DK2858490T5 (en) | 2011-06-10 | 2012-06-12 | Recombinant DNA elements for expression of recombinant proteins in insects |
| DK12750333.2T DK2858489T3 (da) | 2011-06-10 | 2012-06-12 | Rekombinante dna elementer til ekspression af rekombinante proteiner i en værtscelle |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK12750333.2T DK2858489T3 (da) | 2011-06-10 | 2012-06-12 | Rekombinante dna elementer til ekspression af rekombinante proteiner i en værtscelle |
Country Status (8)
| Country | Link |
|---|---|
| EP (2) | EP2858489B1 (enExample) |
| CA (2) | CA2876343A1 (enExample) |
| DK (2) | DK2858490T5 (enExample) |
| IN (1) | IN2014MN02500A (enExample) |
| MX (1) | MX353498B (enExample) |
| PL (2) | PL2858489T3 (enExample) |
| PT (2) | PT2858489T (enExample) |
| WO (6) | WO2012168493A2 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105392362B (zh) | 2012-06-12 | 2018-11-09 | 替代基因表达公司 | 用于在宿主昆虫中表达重组蛋白的杆状病毒dna元件 |
| US9982239B2 (en) | 2012-06-12 | 2018-05-29 | Alternative Gene Expression S.L. | Baculoviral DNA elements for the expression of recombinant proteins in a host cell |
| ES2611302T3 (es) * | 2012-06-12 | 2017-05-08 | Alternative Gene Expression, S.L. | Elementos de ADN recombinante para la expresión de proteínas recombinantes en insectos |
| CN103749393A (zh) * | 2013-12-20 | 2014-04-30 | 铜陵桂生生态养殖有限公司 | 一种降低蝎子死亡率的养殖方法 |
| ES2554561B1 (es) * | 2014-06-16 | 2016-09-30 | Universitat De València | Nuevos promotores derivados de baculovirus con elevada actividad en sistemas de expresión basados en baculovirus |
| PL3350334T3 (pl) | 2015-09-17 | 2020-05-18 | Alternative Gene Expression, S.L. | Ekspresja rekombinowanych białek w poczwarkach trichoplusia ni |
| CN105087606A (zh) * | 2015-09-23 | 2015-11-25 | 天津瑞普生物技术股份有限公司 | 猪圆环病毒2型cap抗原制备方法 |
| CN105238816B (zh) * | 2015-10-26 | 2018-08-24 | 广州汉腾生物科技有限公司 | 一种表达载体 |
| US11572390B2 (en) | 2017-03-27 | 2023-02-07 | The University Of Queensland | Chimeric insect-specific flaviviruses |
| ES2921999T3 (es) | 2018-06-20 | 2022-09-06 | Fatro Spa | Vacunas para la prevención de la enfermedad hemorrágica del conejo |
| CN110964749A (zh) * | 2018-09-29 | 2020-04-07 | 普莱柯生物工程股份有限公司 | 一种在杆状病毒表达系统中高效表达外源蛋白的方法及其应用 |
| WO2026120074A1 (en) | 2024-12-05 | 2026-06-11 | Alternative Gene Expression S.L. | Sedoreoviridae vaccines based on truncated vp2 capsid proteins |
| WO2026139625A1 (en) | 2024-12-26 | 2026-07-02 | Alternative Gene Expression S.L. | Glutamate-oxaloacetate transaminase (got1) – fc (fragment crystallizable) fusion proteins |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU1377395A (en) * | 1993-12-23 | 1995-07-10 | University Technologies International Inc. | Methods of expressing proteins in insect cells and methods of killing insects |
| US5965393A (en) * | 1997-07-01 | 1999-10-12 | National Institute Of Immunology | Method for enhancing foreign gene expression in baculovirus expression vector system |
| RU2158505C2 (ru) * | 1998-06-09 | 2000-11-10 | Совхоз "Тепличный" | Способ приготовления углеводного корма для насекомых-опылителей |
| ES2232308B1 (es) | 2003-11-12 | 2006-10-16 | Laboratorios Calier, S.A. | Dispositivo para la cria de larvas. |
| JP4271122B2 (ja) * | 2004-10-15 | 2009-06-03 | 財団法人 ひろしま産業振興機構 | カイコでの組換えタンパク質製造のためのポリヌクレオチド |
| US8148129B2 (en) * | 2006-06-30 | 2012-04-03 | The Regents Of The University Of California | Generation of potent dominant negative transcriptional inhibitors |
| US8105827B2 (en) * | 2007-09-06 | 2012-01-31 | Academia Sinica | Protein expression systems |
| KR20110081810A (ko) * | 2008-09-02 | 2011-07-14 | 얼터너티브 진 엑스프레션 에스.엘.(얼제넥스) | 곤충 세포에서의 외래 단백질 발현을 위한 곤충-유래 프로모터 |
-
2012
- 2012-06-12 PT PT127503332T patent/PT2858489T/pt unknown
- 2012-06-12 WO PCT/EP2012/061088 patent/WO2012168493A2/en not_active Ceased
- 2012-06-12 CA CA2876343A patent/CA2876343A1/en not_active Abandoned
- 2012-06-12 WO PCT/IB2012/001136 patent/WO2012168788A2/en not_active Ceased
- 2012-06-12 MX MX2014015277A patent/MX353498B/es active IP Right Grant
- 2012-06-12 PL PL12750333T patent/PL2858489T3/pl unknown
- 2012-06-12 EP EP12750333.2A patent/EP2858489B1/en active Active
- 2012-06-12 DK DK12753914.6T patent/DK2858490T5/en active
- 2012-06-12 IN IN2500MUN2014 patent/IN2014MN02500A/en unknown
- 2012-06-12 DK DK12750333.2T patent/DK2858489T3/da active
- 2012-06-12 PL PL12753914T patent/PL2858490T3/pl unknown
- 2012-06-12 CA CA2876641A patent/CA2876641C/en active Active
- 2012-06-12 WO PCT/IB2012/001137 patent/WO2012168789A2/en not_active Ceased
- 2012-06-12 EP EP12753914.6A patent/EP2858490B1/en active Active
- 2012-06-12 WO PCT/EP2012/061081 patent/WO2012168492A2/en not_active Ceased
- 2012-06-12 PT PT127539146T patent/PT2858490T/pt unknown
- 2012-06-13 WO PCT/RU2012/000455 patent/WO2012169939A2/en not_active Ceased
- 2012-06-13 WO PCT/RU2012/000456 patent/WO2012169940A2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO2012168492A2 (en) | 2012-12-13 |
| WO2012168493A2 (en) | 2012-12-13 |
| PT2858490T (pt) | 2016-11-28 |
| WO2012169939A9 (en) | 2013-02-14 |
| MX2014015277A (es) | 2015-12-15 |
| WO2012168493A8 (en) | 2013-04-04 |
| WO2012169940A9 (en) | 2013-02-14 |
| WO2012168789A3 (en) | 2013-05-10 |
| PT2858489T (pt) | 2016-12-14 |
| WO2012168493A3 (en) | 2013-05-23 |
| EP2858489B1 (en) | 2016-11-09 |
| WO2012168789A2 (en) | 2012-12-13 |
| EP2858490A2 (en) | 2015-04-15 |
| WO2012168492A3 (en) | 2013-04-11 |
| WO2012169939A2 (en) | 2012-12-13 |
| WO2012169939A3 (en) | 2013-05-10 |
| EP2858490B1 (en) | 2016-10-26 |
| CA2876641A1 (en) | 2012-12-13 |
| CA2876343A1 (en) | 2012-12-13 |
| WO2012168788A3 (en) | 2013-05-10 |
| WO2012168788A2 (en) | 2012-12-13 |
| BR112014031039A2 (pt) | 2018-05-08 |
| IN2014MN02500A (enExample) | 2015-07-17 |
| WO2012169940A2 (en) | 2012-12-13 |
| WO2012169940A3 (en) | 2013-04-04 |
| PL2858489T3 (pl) | 2017-07-31 |
| EP2858489A2 (en) | 2015-04-15 |
| DK2858489T3 (da) | 2017-01-02 |
| PL2858490T3 (pl) | 2017-08-31 |
| DK2858490T3 (en) | 2016-12-12 |
| MX353498B (es) | 2018-01-16 |
| CA2876641C (en) | 2018-09-25 |
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