DK2753674T3 - Luminescent Lanthanide Chelates Having Three Chromophores and Their Use - Google Patents
Luminescent Lanthanide Chelates Having Three Chromophores and Their Use Download PDFInfo
- Publication number
- DK2753674T3 DK2753674T3 DK12750585.7T DK12750585T DK2753674T3 DK 2753674 T3 DK2753674 T3 DK 2753674T3 DK 12750585 T DK12750585 T DK 12750585T DK 2753674 T3 DK2753674 T3 DK 2753674T3
- Authority
- DK
- Denmark
- Prior art keywords
- group
- phenylethynyl
- compound
- synthesis
- reactive group
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
- C09K11/00—Luminescent, e.g. electroluminescent, chemiluminescent materials
- C09K11/06—Luminescent, e.g. electroluminescent, chemiluminescent materials containing organic luminescent materials
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/40—Acylated substituent nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B57/00—Other synthetic dyes of known constitution
- C09B57/10—Metal complexes of organic compounds not being dyes in uncomplexed form
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
- G01N33/56933—Mycoplasma
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
- C09K2211/00—Chemical nature of organic luminescent or tenebrescent compounds
- C09K2211/18—Metal complexes
- C09K2211/182—Metal complexes of the rare earth metals, i.e. Sc, Y or lanthanide
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6408—Fluorescence; Phosphorescence with measurement of decay time, time resolved fluorescence
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Materials Engineering (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DKPA201100630 | 2011-08-19 | ||
DKPA201100996 | 2011-12-22 | ||
PCT/EP2012/066082 WO2013026790A1 (en) | 2011-08-19 | 2012-08-17 | Luminescent lanthanide chelates having three chromophores and their use |
Publications (1)
Publication Number | Publication Date |
---|---|
DK2753674T3 true DK2753674T3 (en) | 2016-03-21 |
Family
ID=46724401
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK12750585.7T DK2753674T3 (en) | 2011-08-19 | 2012-08-17 | Luminescent Lanthanide Chelates Having Three Chromophores and Their Use |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP2753674B1 (zh) |
JP (1) | JP5818990B2 (zh) |
CN (1) | CN103890137B (zh) |
DK (1) | DK2753674T3 (zh) |
WO (1) | WO2013026790A1 (zh) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP6087953B2 (ja) * | 2011-12-22 | 2017-03-01 | ラジオメーター・トゥルク・オサケユキチュア | 改良された励起特性を有する新規発光ランタニドキレート |
FR3004189B1 (fr) * | 2013-04-04 | 2015-09-04 | Ecole Norm Superieure Lyon | Complexes de lanthanide comprenant au moins deux groupes betaines, utiles comme marqueurs luminescents |
CN106232771B (zh) | 2014-05-02 | 2019-04-30 | 雷度米特图尔库公司 | 镧系螯合物的新发色团结构 |
FR3021325B1 (fr) * | 2014-05-26 | 2018-01-19 | Andre Maisonneuve | Procede de marquage fluorescent d'un substrat, composition fluorescente de marquage et utilisation d'une telle composition |
CN107074815B (zh) * | 2014-10-29 | 2021-06-22 | 雷度米特图尔库公司 | 用于大环镧系螯合物的新型发色结构 |
CN105694858B (zh) * | 2016-03-18 | 2018-02-23 | 北京石油化工学院 | 一种绿色荧光材料及其制备方法 |
CN105973856B (zh) * | 2016-06-08 | 2018-12-18 | 南京工业大学 | 一种用镧系荧光配合物检测及加速β淀粉样蛋白聚集的方法 |
US11614445B2 (en) | 2016-06-09 | 2023-03-28 | Radiometer Turku Oy | Background blockers for binding assays |
FR3068696A1 (fr) | 2017-07-06 | 2019-01-11 | Ecole Normale Superieure De Lyon | Complexes de terbium et de dysprosium avec antenne optimisee, utiles comme marqueurs luminescents |
WO2019179798A1 (en) | 2018-03-20 | 2019-09-26 | Radiometer Turku Oy | Luminescent lanthanide chelates and their use |
US20220315609A1 (en) * | 2019-06-25 | 2022-10-06 | Radiometer Turku Oy | Novel luminescent lanthanide chelate reporters, biospecific binding reactants labelled with novel luminescent lanthanide chelate reporters and their use |
CN111413308B (zh) * | 2020-04-13 | 2023-01-20 | 延吉海关综合技术服务中心 | 一种稀土元素配合物在检测矿泉水中微量亚硝酸根的应用 |
CN113533272B (zh) * | 2021-06-26 | 2024-01-09 | 浙江工商大学 | 一种提高时间分辨荧光信号强度的标记方法及应用 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH01502271A (ja) * | 1987-02-25 | 1989-08-10 | アクアノーティックス コーポレーション | 配位子抽出および再生用のポリアルキルアミン錯体 |
US6080839A (en) * | 1998-06-25 | 2000-06-27 | Wallac Oy | Labeling reactants and their use |
DE60016898T2 (de) * | 1999-02-18 | 2006-03-30 | The Regents Of The University Of California, Oakland | Phthalamid-lanthanid komplexe zur verwendung als lumineszenzmarker |
WO2000048991A1 (en) * | 1999-02-18 | 2000-08-24 | The Regents Of The University Of California | Salicylamide-lanthanide complexes for use as luminescent markers |
US7018851B2 (en) * | 2003-02-13 | 2006-03-28 | Innotrac Diagnostics Oy | Biospecific binding reactants labeled with new luminescent lanthanide chelates and their use |
CA2536783A1 (en) | 2003-08-29 | 2005-03-10 | Wallac Oy | Novel chelating agents and chelates and their use |
EP1694672B1 (en) | 2003-12-18 | 2012-06-20 | Wallac Oy | Novel chelating agents and highly luminescent and stable chelates and their use |
JP2008510806A (ja) * | 2004-08-26 | 2008-04-10 | マリンクロッド・インコーポレイテッド | 腎機能監視用の発光金属錯体 |
WO2008020113A1 (en) | 2006-08-18 | 2008-02-21 | Abacus Diagnostica Oy | Luminescent lanthanide labelling reagents and their use |
CN102124346B (zh) | 2008-07-16 | 2014-01-15 | 雷迪奥米特医学公司 | 凝血酶底物和测定样本中生物活性凝血酶水平的测定法 |
FI20080624A0 (fi) | 2008-11-17 | 2008-11-17 | Wallac Oy | Kelaatteja, kelatoivia yhdisteitä ja niistä johdettuja konjugaatteja |
-
2012
- 2012-08-17 JP JP2014526454A patent/JP5818990B2/ja active Active
- 2012-08-17 DK DK12750585.7T patent/DK2753674T3/en active
- 2012-08-17 WO PCT/EP2012/066082 patent/WO2013026790A1/en active Application Filing
- 2012-08-17 EP EP12750585.7A patent/EP2753674B1/en active Active
- 2012-08-17 CN CN201280051442.8A patent/CN103890137B/zh active Active
Also Published As
Publication number | Publication date |
---|---|
WO2013026790A1 (en) | 2013-02-28 |
CN103890137B (zh) | 2016-08-24 |
JP2014529599A (ja) | 2014-11-13 |
CN103890137A (zh) | 2014-06-25 |
WO2013026790A9 (en) | 2013-05-23 |
EP2753674B1 (en) | 2016-02-10 |
EP2753674A1 (en) | 2014-07-16 |
JP5818990B2 (ja) | 2015-11-18 |
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