DK27383A - Fremgangsmaade til fremstilling af pyrazol(4,3-c)pyridiner - Google Patents

Fremgangsmaade til fremstilling af pyrazol(4,3-c)pyridiner Download PDF

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Publication number
DK27383A
DK27383A DK27383A DK27383A DK27383A DK 27383 A DK27383 A DK 27383A DK 27383 A DK27383 A DK 27383A DK 27383 A DK27383 A DK 27383A DK 27383 A DK27383 A DK 27383A
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DK
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Prior art keywords
pyridines
procedure
preparing pyrazole
pyrazole
preparing
Prior art date
Application number
DK27383A
Other languages
Danish (da)
English (en)
Other versions
DK27383D0 (da
Inventor
Giorgio Winters
Alberto Sala
Domenico Barone
Original Assignee
Lepetit Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lepetit Spa filed Critical Lepetit Spa
Publication of DK27383D0 publication Critical patent/DK27383D0/da
Publication of DK27383A publication Critical patent/DK27383A/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/74—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK27383A 1982-02-17 1983-01-25 Fremgangsmaade til fremstilling af pyrazol(4,3-c)pyridiner DK27383A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8204722 1982-02-17

Publications (2)

Publication Number Publication Date
DK27383D0 DK27383D0 (da) 1983-01-25
DK27383A true DK27383A (da) 1983-08-18

Family

ID=10528419

Family Applications (1)

Application Number Title Priority Date Filing Date
DK27383A DK27383A (da) 1982-02-17 1983-01-25 Fremgangsmaade til fremstilling af pyrazol(4,3-c)pyridiner

Country Status (16)

Country Link
US (1) US4500525A (no)
EP (1) EP0086422B1 (no)
JP (1) JPS58152885A (no)
KR (1) KR900006853B1 (no)
AT (1) ATE30027T1 (no)
AU (1) AU563591B2 (no)
CA (1) CA1225646A (no)
DE (1) DE3373904D1 (no)
DK (1) DK27383A (no)
ES (3) ES519832A0 (no)
GR (1) GR78080B (no)
IE (1) IE55156B1 (no)
IL (1) IL67785A0 (no)
NZ (1) NZ203302A (no)
PH (1) PH23645A (no)
ZA (1) ZA83628B (no)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5137890A (en) * 1990-02-14 1992-08-11 Ortho Pharmaceutical Corporation 4-phenyl tetrahydropyrido(4,3-d)pyrimidines
US5264576A (en) * 1992-10-22 1993-11-23 Hoechst-Roussel Pharmaceuticals Incorporated Pyrazolo[4,3-c]pyridines which are intermediates
DE19834044A1 (de) * 1998-07-29 2000-02-03 Bayer Ag Neue substituierte Pyrazolderivate
MXPA03001422A (es) 2000-08-14 2004-01-26 Johnson & Johnson Pirazoles substituidos.
MXPA03001420A (es) * 2000-08-14 2004-01-26 Johnson & Johnson Pirazoles sustituidos.
US20070117785A1 (en) * 2000-08-14 2007-05-24 Butler Christopher R Substituted pyrazoles and methods of treatment with substituted pyrazoles
US20050101587A9 (en) * 2000-08-14 2005-05-12 Butler Christopher R. Method for treating allergies using substituted pyrazoles
MXPA03001421A (es) * 2000-08-14 2004-01-26 Johnson & Johnson Pirazoles sustituidos.
US20070105841A1 (en) * 2000-08-14 2007-05-10 Breitenbucher J G Method for treating allergies using substituted pyrazoles
US7332494B2 (en) 2000-08-14 2008-02-19 Janssen Pharmaceutica, N.V. Method for treating allergies using substituted pyrazoles
EP1315741A2 (en) 2000-09-06 2003-06-04 Ortho-McNeil Pharmaceutical, Inc. A method for treating allergies
MXPA03001964A (es) * 2000-09-06 2004-03-26 Johnson & Johnson Metodo para el tratamiento de alergias usando pirazoles substituidos.
AU2003231880A1 (en) * 2002-05-30 2003-12-19 Vertex Pharmaceuticals Incorporated Inhibitors of jak and cdk2 protein kinases
MXPA05000947A (es) * 2002-07-25 2005-05-16 Pharmacia Italia Spa Biciclo-pirazoles activos como inhibidores de cinasa, procedimiento para su preparacion y composiciones farmaceuticas que los contienen.
EP2243781A1 (en) * 2003-05-30 2010-10-27 Vertex Pharmaceuticals, Inc. Pyrazolopyridine derivatives as inhibitors of JAK and CDK2 protein kinases
ATE420881T1 (de) 2003-09-17 2009-01-15 Janssen Pharmaceutica Nv Kondensierte heterocyclische verbindungen als modulatoren des serotoninrezeptors
WO2005030776A1 (en) 2003-09-23 2005-04-07 Vertex Pharmaceuticals Incorporated Pyrazolopyrrole derivatives as protein kinase inhibitors
KR100838692B1 (ko) 2007-07-11 2008-06-16 한국화학연구원 7-(3′,4′-디알콕시페닐)-4,5,6,7-테트라히드로피라졸로[1,5-ａ]피리미딘 화합물, 이의 제조방법 및 이를 포함하는천식 및 만성폐쇄성 폐질환을 포함한 염증관련 질환,관절염, 아토피 피부염, 암 및 뇌질환의 치료 및 예방을위한 약제학적 조성물
EP2615916B1 (en) * 2010-09-16 2017-01-04 Merck Sharp & Dohme Corp. Fused pyrazole derivatives as novel erk inhibitors
EA023648B1 (ru) * 2011-09-12 2016-06-30 Санофи ИНДАНИЛЗАМЕЩЕННЫЕ 4,5,6,7-ТЕТРАГИДРО-1H-ПИРАЗОЛО[4,3-с]ПИРИДИНЫ, ИХ ПРИМЕНЕНИЕ В КАЧЕСТВЕ ЛЕКАРСТВЕННОГО СРЕДСТВА И СОДЕРЖАЩИЕ ИХ ФАРМАЦЕВТИЧЕСКИЕ ПРЕПАРАТЫ
CN103930420B (zh) 2011-09-12 2016-05-25 赛诺菲 茚满基取代的4,5,6,7-四氢-1H-吡唑并[4,3-c]吡啶、它们作为药物的用途和包含它们的药物制剂
JP5957525B2 (ja) 2011-09-16 2016-07-27 サノフイ 置換された、４，５，６，７−テトラヒドロ−１Ｈ−ピラゾロ［４，３−ｃ］ピリジン、医薬としてのそれらの使用、及びそれらを含む医薬製剤
EA025240B1 (ru) * 2011-09-16 2016-12-30 Санофи ЗАМЕЩЕННЫЕ 4,5,6,7-ТЕТРАГИДРО-1H-ПИРАЗОЛО[4,3-c]ПИРИДИНЫ, ИХ ПРИМЕНЕНИЕ В КАЧЕСТВЕ ЛЕКАРСТВЕННОГО СРЕДСТВА И ФАРМАЦЕВТИЧЕСКИЕ ПРЕПАРАТЫ, СОДЕРЖАЩИЕ ИХ
US9550779B2 (en) 2014-12-30 2017-01-24 Novira Therapeutics, Inc. Derivatives and methods of treating hepatitis B infections
MA45146A (fr) * 2016-05-24 2021-03-24 Constellation Pharmaceuticals Inc Dérivés de pyrazolopyridine pour le traitement du cancer
US10975077B2 (en) 2016-06-29 2021-04-13 Novira Therapeutics, Inc. Diazepinone derivatives and their use in the treatment of hepatitis B infections
CN109843892B (zh) 2016-06-29 2022-01-25 诺维拉治疗公司 噁二氮杂卓酮衍生物及其在治疗乙型肝炎感染中的用途
KR102638253B1 (ko) 2017-05-31 2024-02-16 케모센트릭스, 인크. C5a 억제제로서의 6-5 융합 고리
AU2018388655C1 (en) * 2017-12-22 2023-03-23 Chemocentryx, Inc. Diaryl substituted 6,5-fused ring compounds as C5aR inhibitors

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3852279A (en) * 1973-03-12 1974-12-03 Squibb & Sons Inc 7-substituted -3,3a,4,5,6,7-hexahydro-3-substituted-2h- pyrazolo (4,3-c)pyridines

Also Published As

Publication number Publication date
IE830328L (en) 1983-08-17
IE55156B1 (en) 1990-06-20
DE3373904D1 (en) 1987-11-05
JPS58152885A (ja) 1983-09-10
KR840003636A (ko) 1984-09-15
DK27383D0 (da) 1983-01-25
ES531981A0 (es) 1985-09-01
ES8500273A1 (es) 1984-10-01
AU1130583A (en) 1983-08-25
ES531980A0 (es) 1985-09-01
AU563591B2 (en) 1987-07-16
EP0086422A2 (en) 1983-08-24
US4500525A (en) 1985-02-19
ATE30027T1 (de) 1987-10-15
JPH0412269B2 (no) 1992-03-04
KR900006853B1 (ko) 1990-09-22
ES8507546A1 (es) 1985-09-01
ES8507547A1 (es) 1985-09-01
CA1225646A (en) 1987-08-18
EP0086422A3 (en) 1984-03-28
ZA83628B (en) 1983-12-28
NZ203302A (en) 1986-08-08
GR78080B (no) 1984-09-26
PH23645A (en) 1989-09-27
EP0086422B1 (en) 1987-09-30
IL67785A0 (en) 1983-05-15
ES519832A0 (es) 1984-10-01

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