DK2694971T3 - Steroidreceptorassays til detektering af tumorceller - Google Patents

Steroidreceptorassays til detektering af tumorceller Download PDF

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Publication number
DK2694971T3
DK2694971T3 DK12716825.0T DK12716825T DK2694971T3 DK 2694971 T3 DK2694971 T3 DK 2694971T3 DK 12716825 T DK12716825 T DK 12716825T DK 2694971 T3 DK2694971 T3 DK 2694971T3
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DK
Denmark
Prior art keywords
tumor cell
cell detection
steroid receptor
receptor assays
assays
Prior art date
Application number
DK12716825.0T
Other languages
English (en)
Inventor
David A Chianese
Original Assignee
Menarini Silicon Biosystems Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Menarini Silicon Biosystems Spa filed Critical Menarini Silicon Biosystems Spa
Application granted granted Critical
Publication of DK2694971T3 publication Critical patent/DK2694971T3/da

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57415—Specifically defined cancers of breast
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57492—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds localized on the membrane of tumor or cancer cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/743—Steroid hormones
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
    • G01N2333/723—Steroid/thyroid hormone superfamily, e.g. GR, EcR, androgen receptor, oestrogen receptor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/54—Determining the risk of relapse

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Endocrinology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
DK12716825.0T 2011-04-01 2012-03-30 Steroidreceptorassays til detektering af tumorceller DK2694971T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161470618P 2011-04-01 2011-04-01
US13/432,248 US20120252038A1 (en) 2011-04-01 2012-03-28 Steroid receptor assays
PCT/US2012/031338 WO2012135560A1 (en) 2011-04-01 2012-03-30 Steroid receptor assays for detecting tumor cells

Publications (1)

Publication Number Publication Date
DK2694971T3 true DK2694971T3 (da) 2020-06-02

Family

ID=46927724

Family Applications (1)

Application Number Title Priority Date Filing Date
DK12716825.0T DK2694971T3 (da) 2011-04-01 2012-03-30 Steroidreceptorassays til detektering af tumorceller

Country Status (20)

Country Link
US (1) US20120252038A1 (da)
EP (1) EP2694971B1 (da)
JP (2) JP2014513283A (da)
KR (1) KR20140019823A (da)
CN (1) CN103608681A (da)
BR (1) BR112013025287A2 (da)
CA (1) CA2831567A1 (da)
CY (1) CY1123191T1 (da)
DK (1) DK2694971T3 (da)
ES (1) ES2793485T3 (da)
HR (1) HRP20200860T1 (da)
HU (1) HUE050711T2 (da)
IL (1) IL228564B (da)
LT (1) LT2694971T (da)
MX (1) MX360225B (da)
PL (1) PL2694971T3 (da)
PT (1) PT2694971T (da)
RS (1) RS60678B1 (da)
SI (1) SI2694971T1 (da)
WO (1) WO2012135560A1 (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10253107B2 (en) * 2012-10-26 2019-04-09 The University Of Queensland Use of endocytosis inhibitors and antibodies for cancer therapy
CN109975097A (zh) * 2019-04-18 2019-07-05 山东师范大学 一种基于适配体的肿瘤细胞染色探针组合

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5292638A (en) * 1990-12-07 1994-03-08 The Regents Of The University Of California Method of determining functional estrogen receptors for prognosis of cancer
CA2077781A1 (en) * 1991-09-23 1993-03-24 James W. Bacus Method and apparatus for automated assay of biological specimens
AU3374597A (en) 1996-06-07 1998-01-05 Immunivest Corporation Magnetic separation employing external and internal gradients
WO1999041613A1 (en) * 1998-02-12 1999-08-19 Immunivest Methods and reagents for the rapid and efficient isolation of circulating cancer cells
BR0207290A (pt) * 2001-02-16 2005-06-07 Immunivest Corp Método para analisar um paciente quanto à presença de uma malignidade, célula maligna isolada das células cultivadas, vacina de tumor, molécula associada com diátese de tumor alterada, métodos para determinar alterações em moléculas associadas com diátese de tumor como um meio para predizer a eficácia da terapia, como um meio para analisar dosagem apropriada para terapia, como um meio para monitorar eficácia da terapia, como um meio para analisar progressão de câncer, para realizar uma biópsia de corpo inteiro em um paciente, e para identificar alterações em uma célula de tumor circulante relativamente a células presentes numa massa de tumor in situ, e, kit de teste para analisar uma amostra de paciente quanto à presença de uma célula maligna não-hematopoiética
JP2005501236A (ja) * 2001-08-23 2005-01-13 イムニベスト・コーポレイション 分析用の細胞および生物学的検体の安定化
IL161357A0 (en) * 2001-10-26 2004-09-27 Immunivest Corp Multiparameter analysis of comprehensive nucleic acids and morphological features on the same sample
CN1871517A (zh) * 2002-02-19 2006-11-29 免疫公司 快速有效分离循环癌细胞的方法和试剂
US7011794B2 (en) 2002-11-25 2006-03-14 Immunivest Corporation Upon a cartridge for containing a specimen sample for optical analysis
WO2004076643A2 (en) * 2003-02-27 2004-09-10 Immunivest Corporation CIRCULATING TUMOR CELLS (CTC’s): EARLY ASSESSMENT OF TIME TO PROGRESSION SURVIVAL AND RESPONSE TO THERAPY IN METASTATIC CANCER PATIENTS
US20040171091A1 (en) * 2003-02-27 2004-09-02 Cell Work, Inc. Standardized evaluation of therapeutic efficacy based on cellular biomarkers
US20090291920A1 (en) * 2006-04-18 2009-11-26 Wellstat Biologics Corporation Detection of steroid receptors on circulating carcinoma cells and treatment
JP5350369B2 (ja) * 2007-05-31 2013-11-27 ダコ デンマーク アクティーゼルスカブ 乳癌治療および予後におけるｅｓｒコピー数変化の利用方法
US20090061456A1 (en) * 2007-08-30 2009-03-05 Allard William J Method for predicting progression free and overall survival at each follow-up time point during therapy of metastatic breast cancer patients using circulating tumor cells
US8071395B2 (en) * 2007-12-12 2011-12-06 The Board Of Trustees Of The Leland Stanford Junior University Methods and apparatus for magnetic separation of cells
JP2010151678A (ja) * 2008-12-25 2010-07-08 Olympus Corp 大腸癌の診断方法および大腸癌診断用キット
WO2011002649A1 (en) * 2009-06-30 2011-01-06 Veridex, Llc Analysis of circulating tumor-related microparticles
EP3306321A1 (en) * 2010-07-07 2018-04-11 The Regents of The University of Michigan Diagnosis and treatment of breast cancer

Also Published As

Publication number Publication date
HUE050711T2 (hu) 2020-12-28
MX2013011428A (es) 2014-06-23
WO2012135560A1 (en) 2012-10-04
PT2694971T (pt) 2020-06-16
HRP20200860T1 (hr) 2020-09-04
SI2694971T1 (sl) 2020-09-30
KR20140019823A (ko) 2014-02-17
JP2018021934A (ja) 2018-02-08
CY1123191T1 (el) 2021-10-29
MX360225B (es) 2018-10-25
JP6707505B2 (ja) 2020-06-10
ES2793485T3 (es) 2020-11-16
IL228564A0 (en) 2013-12-31
EP2694971B1 (en) 2020-03-04
RS60678B1 (sr) 2020-09-30
JP2014513283A (ja) 2014-05-29
PL2694971T3 (pl) 2020-11-02
IL228564B (en) 2018-08-30
CN103608681A (zh) 2014-02-26
US20120252038A1 (en) 2012-10-04
BR112013025287A2 (pt) 2017-11-14
EP2694971A1 (en) 2014-02-12
LT2694971T (lt) 2020-08-10
CA2831567A1 (en) 2012-10-04

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