MX360225B - Ensayos de receptores de esteroides para detectar celulas tumorales. - Google Patents

Ensayos de receptores de esteroides para detectar celulas tumorales.

Info

Publication number
MX360225B
MX360225B MX2013011428A MX2013011428A MX360225B MX 360225 B MX360225 B MX 360225B MX 2013011428 A MX2013011428 A MX 2013011428A MX 2013011428 A MX2013011428 A MX 2013011428A MX 360225 B MX360225 B MX 360225B
Authority
MX
Mexico
Prior art keywords
tumor cells
steroid receptor
receptor assays
detecting tumor
enumeration
Prior art date
Application number
MX2013011428A
Other languages
English (en)
Other versions
MX2013011428A (es
Inventor
David A Chianese
Original Assignee
Janssen Diagnostics Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Diagnostics Llc filed Critical Janssen Diagnostics Llc
Publication of MX2013011428A publication Critical patent/MX2013011428A/es
Publication of MX360225B publication Critical patent/MX360225B/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57415—Specifically defined cancers of breast
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57492—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds localized on the membrane of tumor or cancer cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/743—Steroid hormones
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
    • G01N2333/723—Steroid/thyroid hormone superfamily, e.g. GR, EcR, androgen receptor, oestrogen receptor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/54—Determining the risk of relapse

Abstract

La presente invención se refiere a métodos para la detección, enumeración y análisis de células tumorales circulantes que expresan receptores de esferoides, particularmente receptores de estrógeno; estos métodos son útiles para la exploración y determinación de las etapas del cáncer, desarrollo regímenes de tratamiento y para monitorear las respuestas al tratamiento, recurrencia del cáncer o similares; además, se proporcionan kits de pruebas que facilitan la detección, enumeración y análisis de dichas células tumorales circulantes.
MX2013011428A 2011-04-01 2012-03-30 Ensayos de receptores de esteroides para detectar celulas tumorales. MX360225B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161470618P 2011-04-01 2011-04-01
US13/432,248 US20120252038A1 (en) 2011-04-01 2012-03-28 Steroid receptor assays
PCT/US2012/031338 WO2012135560A1 (en) 2011-04-01 2012-03-30 Steroid receptor assays for detecting tumor cells

Publications (2)

Publication Number Publication Date
MX2013011428A MX2013011428A (es) 2014-06-23
MX360225B true MX360225B (es) 2018-10-25

Family

ID=46927724

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013011428A MX360225B (es) 2011-04-01 2012-03-30 Ensayos de receptores de esteroides para detectar celulas tumorales.

Country Status (20)

Country Link
US (1) US20120252038A1 (es)
EP (1) EP2694971B1 (es)
JP (2) JP2014513283A (es)
KR (1) KR20140019823A (es)
CN (1) CN103608681A (es)
BR (1) BR112013025287A2 (es)
CA (1) CA2831567A1 (es)
CY (1) CY1123191T1 (es)
DK (1) DK2694971T3 (es)
ES (1) ES2793485T3 (es)
HR (1) HRP20200860T1 (es)
HU (1) HUE050711T2 (es)
IL (1) IL228564B (es)
LT (1) LT2694971T (es)
MX (1) MX360225B (es)
PL (1) PL2694971T3 (es)
PT (1) PT2694971T (es)
RS (1) RS60678B1 (es)
SI (1) SI2694971T1 (es)
WO (1) WO2012135560A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10253107B2 (en) * 2012-10-26 2019-04-09 The University Of Queensland Use of endocytosis inhibitors and antibodies for cancer therapy
CN109975097A (zh) * 2019-04-18 2019-07-05 山东师范大学 一种基于适配体的肿瘤细胞染色探针组合

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5292638A (en) * 1990-12-07 1994-03-08 The Regents Of The University Of California Method of determining functional estrogen receptors for prognosis of cancer
CA2077781A1 (en) * 1991-09-23 1993-03-24 James W. Bacus Method and apparatus for automated assay of biological specimens
US5985153A (en) 1996-06-07 1999-11-16 Immunivest Corporation Magnetic separation apparatus and methods employing an internal magnetic capture gradient and an external transport force
DE69941689D1 (de) * 1998-02-12 2010-01-07 Univ Texas Verfahren und reagenzien zur raschen und effizienten isolierung zirkulierender krebszellen
JP2005516217A (ja) * 2001-02-16 2005-06-02 イムニベスト・コーポレイション 循環している癌細胞の急速かつ効果的な単離のための方法および試薬
CN1571634A (zh) * 2001-08-23 2005-01-26 免疫公司 用于分析的细胞和生物学标本的稳定
EP1438419A2 (en) * 2001-10-26 2004-07-21 Immunivest Corporation Multiparameter analysis of comprehensive nucleic acids and morphological features on the same sample
CN1871517A (zh) * 2002-02-19 2006-11-29 免疫公司 快速有效分离循环癌细胞的方法和试剂
US7011794B2 (en) 2002-11-25 2006-03-14 Immunivest Corporation Upon a cartridge for containing a specimen sample for optical analysis
WO2004077021A2 (en) * 2003-02-27 2004-09-10 Lesko Stephen A Standardized evaluation of therapeutic efficacy based on cellular biomarkers
DE602004030220D1 (de) * 2003-02-27 2011-01-05 Veridex Llc ZIRKULIERENDE TUMORZELLEN (CTC's): FRÜHE BEURTEILUNG VON TIME-TO-PROGRESSION, ÜBERLEBEN UND ANSPRECHEN AUF THERAPIE BEI PATIENTEN MIT METASTASIERTEM KREBS
EP2008107A4 (en) * 2006-04-18 2009-12-23 Wellstat Biologics Corp DETECTION OF STEROID RECEPTORS IN CIRCULATIVE CANCER CELLS AND TREATMENT
CA2688049A1 (en) * 2007-05-31 2008-12-04 Dako Denmark A/S Methods for utilizing esr copy number changes in breast cancer treatments and prognoses
US20090061456A1 (en) * 2007-08-30 2009-03-05 Allard William J Method for predicting progression free and overall survival at each follow-up time point during therapy of metastatic breast cancer patients using circulating tumor cells
WO2009076560A2 (en) * 2007-12-12 2009-06-18 The Board Of Trustees Of The Leland Stanford Junior University Method and apparatus for magnetic separation of cells
JP2010151678A (ja) * 2008-12-25 2010-07-08 Olympus Corp 大腸癌の診断方法および大腸癌診断用キット
WO2011002649A1 (en) * 2009-06-30 2011-01-06 Veridex, Llc Analysis of circulating tumor-related microparticles
DK2591363T3 (en) * 2010-07-07 2017-12-11 Univ Michigan Regents DIAGNOSIS AND TREATMENT OF BREAST CANCER

Also Published As

Publication number Publication date
JP6707505B2 (ja) 2020-06-10
IL228564A0 (en) 2013-12-31
EP2694971A1 (en) 2014-02-12
PL2694971T3 (pl) 2020-11-02
HRP20200860T1 (hr) 2020-09-04
HUE050711T2 (hu) 2020-12-28
BR112013025287A2 (pt) 2017-11-14
CA2831567A1 (en) 2012-10-04
EP2694971B1 (en) 2020-03-04
SI2694971T1 (sl) 2020-09-30
IL228564B (en) 2018-08-30
US20120252038A1 (en) 2012-10-04
PT2694971T (pt) 2020-06-16
CN103608681A (zh) 2014-02-26
MX2013011428A (es) 2014-06-23
CY1123191T1 (el) 2021-10-29
ES2793485T3 (es) 2020-11-16
LT2694971T (lt) 2020-08-10
KR20140019823A (ko) 2014-02-17
DK2694971T3 (da) 2020-06-02
RS60678B1 (sr) 2020-09-30
WO2012135560A1 (en) 2012-10-04
JP2014513283A (ja) 2014-05-29
JP2018021934A (ja) 2018-02-08

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