DK2694640T3 - Reversion af effekterne af tumormikromiljø ved anvendelse af kimæriske cytokinreceptorer - Google Patents

Reversion af effekterne af tumormikromiljø ved anvendelse af kimæriske cytokinreceptorer

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Publication number
DK2694640T3
DK2694640T3 DK12767723.5T DK12767723T DK2694640T3 DK 2694640 T3 DK2694640 T3 DK 2694640T3 DK 12767723 T DK12767723 T DK 12767723T DK 2694640 T3 DK2694640 T3 DK 2694640T3
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DK
Denmark
Prior art keywords
reversion
chemical
environment
effects
tumor micro
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Application number
DK12767723.5T
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Danish (da)
English (en)
Inventor
Ann Marie Leen
Juan F Vera
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Baylor College Medicine
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Publication of DK2694640T3 publication Critical patent/DK2694640T3/da

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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/30—Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
    • A61K40/31—Chimeric antigen receptors [CAR]
    • A—HUMAN NECESSITIES
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    • A61K40/00—Cellular immunotherapy
    • A61K40/30—Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
    • A61K40/35—Cytokines
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    • A61K40/41—Vertebrate antigens
    • A61K40/42—Cancer antigens
    • A61K40/4238—Regulators of development
    • A61K40/424—Apoptosis related proteins, e.g. survivin or livin
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    • A61K40/41—Vertebrate antigens
    • A61K40/42—Cancer antigens
    • A61K40/4256—Tumor associated carbohydrates
    • A61K40/4257—Mucins, e.g. MUC-1
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    • A61K40/41—Vertebrate antigens
    • A61K40/42—Cancer antigens
    • A61K40/4264—Cancer antigens from embryonic or fetal origin
    • A61K40/4266—Carcinoembryonic antigen [CEA]
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    • A61K40/41—Vertebrate antigens
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DK12767723.5T 2011-04-08 2012-04-05 Reversion af effekterne af tumormikromiljø ved anvendelse af kimæriske cytokinreceptorer DK2694640T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161473457P 2011-04-08 2011-04-08
PCT/US2012/032322 WO2012138858A1 (en) 2011-04-08 2012-04-05 Reversing the effects of the tumor microenvironment using chimeric cytokine receptors

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DK2694640T3 true DK2694640T3 (da) 2017-11-20

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DK12767723.5T DK2694640T3 (da) 2011-04-08 2012-04-05 Reversion af effekterne af tumormikromiljø ved anvendelse af kimæriske cytokinreceptorer

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Country Link
US (2) US10548921B2 (https=)
EP (2) EP2694640B1 (https=)
JP (3) JP6066991B2 (https=)
CN (2) CN107164330A (https=)
AU (3) AU2012240135B2 (https=)
CA (1) CA2832569A1 (https=)
DK (1) DK2694640T3 (https=)
ES (1) ES2649967T3 (https=)
MX (2) MX347656B (https=)
NO (1) NO2724929T3 (https=)
NZ (3) NZ723731A (https=)
WO (1) WO2012138858A1 (https=)

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