CN107164330A - 使用嵌合细胞因子受体逆转肿瘤微环境的影响 - Google Patents
使用嵌合细胞因子受体逆转肿瘤微环境的影响 Download PDFInfo
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- CN107164330A CN107164330A CN201710136120.8A CN201710136120A CN107164330A CN 107164330 A CN107164330 A CN 107164330A CN 201710136120 A CN201710136120 A CN 201710136120A CN 107164330 A CN107164330 A CN 107164330A
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- A61K40/41—Vertebrate antigens
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161473457P | 2011-04-08 | 2011-04-08 | |
| US61/473,457 | 2011-04-08 | ||
| CN201280024856.1A CN103582699B (zh) | 2011-04-08 | 2012-04-05 | 使用嵌合细胞因子受体逆转肿瘤微环境的影响 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201280024856.1A Division CN103582699B (zh) | 2011-04-08 | 2012-04-05 | 使用嵌合细胞因子受体逆转肿瘤微环境的影响 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107164330A true CN107164330A (zh) | 2017-09-15 |
Family
ID=46969548
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710136120.8A Pending CN107164330A (zh) | 2011-04-08 | 2012-04-05 | 使用嵌合细胞因子受体逆转肿瘤微环境的影响 |
| CN201280024856.1A Active CN103582699B (zh) | 2011-04-08 | 2012-04-05 | 使用嵌合细胞因子受体逆转肿瘤微环境的影响 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201280024856.1A Active CN103582699B (zh) | 2011-04-08 | 2012-04-05 | 使用嵌合细胞因子受体逆转肿瘤微环境的影响 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US10548921B2 (https=) |
| EP (2) | EP2694640B1 (https=) |
| JP (3) | JP6066991B2 (https=) |
| CN (2) | CN107164330A (https=) |
| AU (3) | AU2012240135B2 (https=) |
| CA (1) | CA2832569A1 (https=) |
| DK (1) | DK2694640T3 (https=) |
| ES (1) | ES2649967T3 (https=) |
| MX (2) | MX347656B (https=) |
| NO (1) | NO2724929T3 (https=) |
| NZ (3) | NZ723731A (https=) |
| WO (1) | WO2012138858A1 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116284449A (zh) * | 2023-02-27 | 2023-06-23 | 深圳市先康达生命科学有限公司 | 增强型TGF-βR嵌合受体及其应用 |
Families Citing this family (116)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9249423B2 (en) | 2007-02-02 | 2016-02-02 | Yale University | Method of de-differentiating and re-differentiating somatic cells using RNA |
| US10155038B2 (en) | 2007-02-02 | 2018-12-18 | Yale University | Cells prepared by transient transfection and methods of use thereof |
| US8956860B2 (en) | 2009-12-08 | 2015-02-17 | Juan F. Vera | Methods of cell culture for adoptive cell therapy |
| PH12013501201A1 (en) | 2010-12-09 | 2013-07-29 | Univ Pennsylvania | Use of chimeric antigen receptor-modified t cells to treat cancer |
| CN104411819B (zh) * | 2012-06-11 | 2019-05-10 | 威尔逊沃夫制造公司 | 用于过继细胞疗法的改进的细胞培养方法 |
| IN2015KN00329A (https=) | 2012-08-09 | 2015-07-10 | Univ Leland Stanford Junior | |
| AU2013204922B2 (en) | 2012-12-20 | 2015-05-14 | Celgene Corporation | Chimeric antigen receptors |
| SG11201507026WA (en) * | 2013-02-06 | 2015-10-29 | Anthrogenesis Corp | Modified t lymphocytes having improved specificity |
| TW201446794A (zh) | 2013-02-20 | 2014-12-16 | Novartis Ag | 利用抗-cd123嵌合抗原受體工程化t細胞之初級人類白血病有效靶向 |
| DK2958943T3 (da) | 2013-02-20 | 2019-12-09 | Univ Pennsylvania | Behandling af cancer ved anvendelse af humaniseret anti-EGFRvIII kimær antigenreceptor |
| AU2014240083C1 (en) | 2013-03-15 | 2019-10-24 | Celgene Corporation | Modified T lymphocytes |
| EP2970426B1 (en) | 2013-03-15 | 2019-08-28 | Michael C. Milone | Targeting cytotoxic cells with chimeric receptors for adoptive immunotherapy |
| UY35468A (es) | 2013-03-16 | 2014-10-31 | Novartis Ag | Tratamiento de cáncer utilizando un receptor quimérico de antígeno anti-cd19 |
| CA2909701C (en) * | 2013-04-17 | 2022-12-06 | Baylor College Of Medicine | Immunosuppressive tgf-.beta. signal converter |
| WO2014201319A1 (en) * | 2013-06-14 | 2014-12-18 | The University Of Houston System | Targeting tumor neovasculature with modified chimeric antigen receptors |
| EP3021853A1 (en) * | 2013-07-18 | 2016-05-25 | Baylor College Of Medicine | Method of enhancing potency of immune cells |
| WO2015042705A1 (en) | 2013-09-24 | 2015-04-02 | Medicenna Biopharma Inc. | Interleukin-4 receptor-binding fusion proteins and uses thereof |
| ES2918501T3 (es) | 2013-12-19 | 2022-07-18 | Novartis Ag | Receptores de antígenos quiméricos de mesotelina humana y usos de los mismos |
| US10287354B2 (en) | 2013-12-20 | 2019-05-14 | Novartis Ag | Regulatable chimeric antigen receptor |
| US11028143B2 (en) | 2014-01-21 | 2021-06-08 | Novartis Ag | Enhanced antigen presenting ability of RNA CAR T cells by co-introduction of costimulatory molecules |
| AU2015244039B2 (en) | 2014-04-07 | 2021-10-21 | Novartis Ag | Treatment of cancer using anti-CD19 chimeric antigen receptor |
| KR20160145802A (ko) * | 2014-04-23 | 2016-12-20 | 보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템 | 요법에 사용하기 위한 키메라 항원 수용체 (car) 및 이의 제조 방법 |
| US11542488B2 (en) | 2014-07-21 | 2023-01-03 | Novartis Ag | Sortase synthesized chimeric antigen receptors |
| KR20170037625A (ko) | 2014-07-21 | 2017-04-04 | 노파르티스 아게 | Cll-1 키메라 항원 수용체를 사용한 암의 치료 |
| SG10201913765YA (en) | 2014-07-21 | 2020-03-30 | Novartis Ag | Treatment of cancer using a cd33 chimeric antigen receptor |
| TWI750110B (zh) | 2014-07-21 | 2021-12-21 | 瑞士商諾華公司 | 使用人類化抗-bcma嵌合抗原受體治療癌症 |
| JP6631865B2 (ja) * | 2014-08-11 | 2020-01-15 | 日本化薬株式会社 | TGFβ阻害機能を持つキメラタンパク質 |
| ES2791248T3 (es) | 2014-08-19 | 2020-11-03 | Novartis Ag | Receptor antigénico quimérico (CAR) anti-CD123 para su uso en el tratamiento del cáncer |
| KR20250067191A (ko) | 2014-09-17 | 2025-05-14 | 노파르티스 아게 | 입양 면역요법을 위한 키메라 수용체에 의한 세포독성 세포의 표적화 |
| KR20170068504A (ko) | 2014-10-08 | 2017-06-19 | 노파르티스 아게 | 키메라 항원 수용체 요법에 대한 치료 반응성을 예측하는 바이오마커 및 그의 용도 |
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