DK2675503T3 - Autoinjektor - Google Patents

Autoinjektor Download PDF

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Publication number
DK2675503T3
DK2675503T3 DK12703837.0T DK12703837T DK2675503T3 DK 2675503 T3 DK2675503 T3 DK 2675503T3 DK 12703837 T DK12703837 T DK 12703837T DK 2675503 T3 DK2675503 T3 DK 2675503T3
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DK
Denmark
Prior art keywords
carrier
chassis
proximal
auto
ramp
Prior art date
Application number
DK12703837.0T
Other languages
English (en)
Inventor
Simon Francis Brereton
Thomas Kemp
Matthew Ekman
Rosie Burnell
Original Assignee
Sanofi Sa
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Publication of DK2675503T3 publication Critical patent/DK2675503T3/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2033—Spring-loaded one-shot injectors with or without automatic needle insertion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M5/2422—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic using emptying means to expel or eject media, e.g. pistons, deformation of the ampoule, or telescoping of the ampoule
    • A61M5/2429—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic using emptying means to expel or eject media, e.g. pistons, deformation of the ampoule, or telescoping of the ampoule by telescoping of ampoules or carpules with the syringe body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31501—Means for blocking or restricting the movement of the rod or piston
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31566—Means improving security or handling thereof
    • A61M5/3157—Means providing feedback signals when administration is completed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31578—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod
    • A61M5/3158—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod performed by axially moving actuator operated by user, e.g. an injection button
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3202—Devices for protection of the needle before use, e.g. caps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3202—Devices for protection of the needle before use, e.g. caps
    • A61M5/3204—Needle cap remover, i.e. devices to dislodge protection cover from needle or needle hub, e.g. deshielding devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
    • A61M5/321—Means for protection against accidental injuries by used needles
    • A61M5/3243—Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
    • A61M5/3257—Semi-automatic sleeve extension, i.e. in which triggering of the sleeve extension requires a deliberate action by the user, e.g. manual release of spring-biased extension means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
    • A61M5/321—Means for protection against accidental injuries by used needles
    • A61M5/3243—Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
    • A61M5/326—Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/2006—Having specific accessories
    • A61M2005/2013—Having specific accessories triggering of discharging means by contact of injector with patient body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/206—With automatic needle insertion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/2073—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically preventing premature release, e.g. by making use of a safety lock
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/2073—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically preventing premature release, e.g. by making use of a safety lock
    • A61M2005/208—Release is possible only when device is pushed against the skin, e.g. using a trigger which is blocked or inactive when the device is not pushed against the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
    • A61M5/321—Means for protection against accidental injuries by used needles
    • A61M5/3243—Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
    • A61M5/3245—Constructional features thereof, e.g. to improve manipulation or functioning
    • A61M2005/3247—Means to impede repositioning of protection sleeve from needle covering to needle uncovering position
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/581—Means for facilitating use, e.g. by people with impaired vision by audible feedback
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/582—Means for facilitating use, e.g. by people with impaired vision by tactile feedback
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/583—Means for facilitating use, e.g. by people with impaired vision by visual feedback
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/46—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for controlling depth of insertion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/50—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile
    • A61M5/5086—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile for indicating if defective, used, tampered with or unsterile
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04C—ROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; ROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT PUMPS
    • F04C2270/00—Control; Monitoring or safety arrangements
    • F04C2270/04—Force
    • F04C2270/042—Force radial
    • F04C2270/0421—Controlled or regulated
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T403/00—Joints and connections
    • Y10T403/32—Articulated members
    • Y10T403/32254—Lockable at fixed position
    • Y10T403/32467—Telescoping members
    • Y10T403/32475—Telescoping members having detent
    • Y10T403/32501—Cam or wedge

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Environmental & Geological Engineering (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Claims (12)

1. Autoinjektor (1) til administration af en dosis af et væskeformigt medikament (M), der omfatter: - et aflangt hylster (12), der er beregnet til at blive holdt af en bruger, - et rørformet chassis (2) , der kan skydes ind i hylsteret (12) og påvirkes mod hylsteret (12), så det stikker frem proksimalt fra hylsteret (12) , - en sprøjte (3) med en injektionskanyle (4), en drivfjeder (8) og et stempel (9) til fremadrettet belastning af drivfjederen (8) mod en prop (6) i sprøjten (3), - en udløserknap (13), der er anbragt distalt i eller på hylsteret (12) , hvor udløserknappen (13) indledningsvis er koblet til hylsteret (12) på en måde, så den stikker frem distalt fra hylsteret (12), og er i indgreb med chassiset (2) på en måde, der forhindrer, at udløserknappen (13) afkobles fra hylsteret (12), og således forhindrer nedtrykning af udløserknappen (13) i en indledende position, hvor hylsteret (12) er indrettet til at translatere i den proksimale retning (P) mod påvirkningen i forhold til chassiset (2) til derved også translatering af udløserknappen (13), hvilket frigør indgrebet med chassiset (2) til muliggørelse af nedtrykning af udløserknappen (13), hvor der er tilvejebragt en bæreenhedsdelindretning, der omfatter en rørformet bæreenhed (7), der er glidbart anbragt i forhold til chassiset (2) inde i hylsteret (12), hvor bæreenheden (7) er indrettet til at indeholde sprøjten (3) med injektionskanylen (4), hvor sprøjten (3) kan låses til samlet aksial translation med bæreenheden (7), der er kendetegnet ved, at bæreenheden (7) ydermere er indrettet til at indeholde drivfjederen (8) og stemplet (9), hvor udløserknappen (13) omfatter mindst én proksimal stav (13.1), der er indrettet til at være i et rampe-indgreb med hylsteret (12) på en måde til indadrettet afbøjning af den proksimale stav (13.1) og afkobling af denne fra hylsteret (12), når udløserknappen (13) presses i den proksimale retning (P) mod hylsteret (12), hvor den proksimale stav (13.1) i den indledende position indadrettet støder op til bæreenheden (7), hvilket forhindrer indadrettet afbøjning, hvor bæreenheden indledningsvis er koblet til chassiset (2) til samlet aksial translation ved hjælp af en gribermekanisme (18), hvor gribermekanismen (18) er indrettet til at afkoble chassiset (2) fra bæreenheden (7) ved nedtrykning af udløserknappen (13), hvilket åbner mulighed for, at bæreenheden (7) kan bevæge sig i forhold til chassiset (2), hvor et første vindue (7.11) i bæreenheden (7) er indrettet til muliggørelse af indadrettet afbøjning af den proksimale stav (13.1), når hylsteret (12) translateres i den proksimale retning (P) fra den indledende position, hvor den proksimale stav (13.1) er indrettet til at gå i indgreb i det første vindue (7.11) ved nedtrykning af udløserknappen (13), der støder op til bæreenheden (7), til translation af denne i den proksimale retning (P) i forhold til chassiset (2), hvor hylsteret (12) er indrettet til udadrettet at støde op til den proksimale stav (13.1), der er i indgreb i det første vindue (7.11), hvilket forhindrer, at den afkobles fra bæreenheden (7), således at udløserknappen (13) låser i en mere proksimal position, når den er nedtrykket.
2. Autoinjektor (1) ifølge krav 1, der er kendetegnet ved, at en kontrolfjeder (19) er anbragt omkring bæreenheden (7), hvor der er tilvejebragt en kanyleindføringskontrolmekanisme (24) til kobling af en proksimal ende af kontrolfjederen (19) til enten bæreenheden (7) til fremføring af denne til kanyleindføring eller til chassiset (2) til kanyletilbagetrækning afhængig af den relative aksiale position af bæreenheden (7) og chassiset (2), hvor en stempeludløsningsmekanisme (27) er indrettet til udløsning af stemplet (9) til injektion, når bæreenheden (7) har i det mindste næsten nået en injektionsdybde under kanyleindføring, hvor gribermekanismen (18), når den frigøres, er indrettet til muliggørelse af, at bæreenheden (7) kan bevæge sig i forhold til chassiset (2) til opnåelse af, at kanyleindføringskontrolmekanismen (24) skifter den proksimale ende af kontrolfjederen (19) til bæreenheden (7) til kanyleindføring, hvor en sprøjtetilbagetrækningskontrolmekanisme (25) er indrettet til at koble en distal ende af kontrolfjederen (19) til enten bæreenheden (7) til kanyletilbagetrækning eller ellers til hylsteret (12).
3. Autoinjektor (1) ifølge krav 2, der er kendetegnet ved, at kanyleindføringskontrolmekanismen (24) omfatter en første krave (20), der påvirkes af kontrolfjederen i en proksimal retning (P) , hvor mindst én elastisk stav (20.1) er anbragt proksimalt på den første krave (20), hvor respektive planforsænkninger er anbragt i bæreenheden (7) og hylsteret (2), hvor en tværgående forlængelse af et hoved på den elastiske stav (20.1) er bredere end et mellemrum mellem bæreenheden (7) og chassiset (2), hvilket medfører, at hovedet på den elastiske stav (20.1) støder op til en distal flade af planforsænkningen i chassiset (2), idet det forhindres i at blive afbøjet i en indadgående retning (I) af bæreenheden (7), eller støder op til en distal flade af planforsænkningen i bæreenheden (7), idet det forhindres i at blive afbøjet i en udadgående retning (O) af chassiset (2), til derved fremadretning af belastningen fra kontrolfjederen (19) mod bæreenheden (7) til kanyleindføring, hvor den elastiske stav (20.1) er indrettet til at blive skiftet mellem chassiset (2) og bæreenheden (7) ved rampe-indgreb af hovedet med de distale flader under belastning af kontrolfjederen (19) afhængig af den relative længdegående position mellem chassiset (2) og bæreenheden (7).
4. Autoinjektor (1) ifølge et af kravene 2 eller 3, der er kendetegnet ved, at stemplet (9) i stempeludløsningsmekanismen (27) i et indledende stadie er låst til bæreenheden (7) ved hjælp af et rampe-indgreb med bæreenheden (7) og ved at være forhindret i at rotere ud af dette rampe-indgreb afhængig af en relativ længdegående position af bæreenheden (7) i hylsteret (12), hvor stemplet (9) er indrettet til at blive udløst ved rotation ud af rampe-indgrebet, når kanylen (4) når i det mindste næsten en prædefineret injektionsdybde ved translation af bæreenheden (7) i den proksimale retning (P) til fremføring af kanylen (4) forbi en proksimal ende af autoinjektoren (1) .
5. Autoinjektor (1) ifølge krav 4, der er kendetegnet ved, at bæreenheden (7) har en længdegående åbning (7.9), hvor et udadrettet fremspring (9.1) er anbragt på stemplet (9) på en måde, så det går i indgreb med en flade (7.8) på bæreenheden (7) i åbningen (7.9), hvor mindst den ene af det udadrettede fremspring (9.1) eller fladen (7.8) på bæreenheden (7) har en rampe, så stemplet (9) tvinges til at rotere, når det translateres, hvor en indadrettet, længdegående ribbe (21.5), der er forbundet til hylsteret (12) , stikker frem indadrettet ind i den længdegående åbning (7.9) på en måde, som forhindrer afkobling af det udadrettede fremspring (9.1) fra fladen (7.8) på bæreenheden (7) før translation af bæreenheden (7) til fremføring af kanylen (4) , og hvor det udadrettede fremspring (9.1) kommer fri af den indadrettede, længdegående ribbe (21.5) ved translation af bæreenheden (7) til fremføring af kanylen (4), så det roterer forbi en proksimal ende af den indadrettede, længdegående ribbe (21.5) som følge af dets rampe-indgreb med bæreenheden (7) under belastning af drivfjederen (8) .
6. Autoinjektor (1) ifølge krav 5, der er kendetegnet ved, at den indadrettede, længdegående ribbe (21.5) er anbragt på en anden krave (21), der er anbragt i hylsteret (12) og indledningsvis låst til hylsteret (12) til samlet aksial translation, hvilken anden krave (21) er en del af en sprøjtetilbagetrækningskontrolmekanisme (25), hvor sprøjtetilbagetrækningskontrolmekanismen (25) er indrettet til at blive koblet fra hylsteret (12) og koblet til bæreenheden (7), når hylsteret (12) bevæges i den distale retning (D) fra en position med kanylen (4) i injektionsdybden, hvor en kontrolfjeder (19) er anbragt i hylsteret (12) omkring bæreenheden (7), hvilken kontrolfjeder (19) virker mellem den anden krave (21) og en proksimal første krave (20) til påvirkning af hylsteret (12) eller bæreenheden (7) i den distale retning (D).
7. Autoinjektor (1) ifølge et af kravene 1 til 6, der er kendetegnet ved, at gribermekanismen (18) omfatter en elastisk stav (2.1) på chassiset (2) og en rombisk rampedel (7.1) på bæreenheden (7), hvor den elastiske stav (2.1) er i det væsentlige lige, når den er relakseret, og har et første stavhoved (2.2), der er indrettet til at interagere i et rampe-indgreb med en proksimal fjerde rampe (7.2) eller en distal femte rampe (7.3) på den rombiske rampedel (7.1) på en sådan måde, at påføring af en translationskraft på bæreenheden (7) i forhold til chassiset (2) i den proksimale retning (P) med det første stavhoved (2.2) i indgreb med den fjerde rampe (7.2) afbøjer den elastiske stav (2.1) i den ene tværgående retning (0, I), når en forudbestemt værdi af translationskraften, der mindst afhænger af elasticiteten af den elastiske stav (2.1), overstiges til muliggørelse af, at det første stavhoved (2.2) vandrer langs den ene tværgående side af den rombiske rampedel (7.1) ved fortsat relativ translation af komponenterne (2, 7), hvor den elastiske stav (2.1) får mulighed for at relaksere, når det første stavhoved (2.2) har nået den femte rampe (7.3) til derved kobling af dette på en måde, således at påføring af en translationskraft på bæreenheden (7) i den distale retning (D) afbøjer den elastiske stav (2.1) i den anden tværgående retning (I, 0), når en forudbestemt værdi af translationskraften, der mindst afhænger af elasticiteten af den elastiske stav (2.1), overstiges til muliggørelse af, at det første stavhoved (2.2) vandrer langs den anden tværgående side af den rombiske rampedel (7.1) ved fortsat translation af bæreenheden (7).
8. Autoinjektor (1) ifølge et af kravene 1 til 7, der er kendetegnet ved, at hylsteret (12) er indrettet til at låse gribermekanismen (18) ), før det translateres i den proksimale retning (P) i forhold til chassiset (2), når chassiset (2) trykkes mod injektionsstedet, hvor hylsteret (12), når det translateres til en fremskudt position i den proksimale retning (P) , er indrettet til at låse låsemekanismen (18) op, hvorved det gøres operabelt.
9. Autoinjektor (1) ifølge et af kravene 2 til 8, der er kendetegnet ved, at sprøjtetilbagetrækningskontrolmekanismen (25) omfatter den anden krave (21), der hviler mod den distale ende af kontrolfjederen (19) og har en elastisk proksimal stav (21.1) med et andet stavhoved (21.2), der har en indadrettet knop (21.3), hvor det andet stavhoved (21.2) er indrettet til at være i et rampe-indgreb med en anden hylstergriber (12.2) i hylsteret (12) på en måde, der rampe-placerer det andet stavhoved (21.1) i den indadgående retning (I) under belastning af kontrolfjederen (19) i den distale retning (D) , hvor den indadrettede knop (21.3) er anbragt, så den indadrettet støder op til bæreenheden (7) til forhindring af indadrettet afbøjning af det andet stavhoved (21.1) og holder den anden krave (21) låst til hylsteret (12), hvor en tredje planforsænkning (7.7) er anbragt i bæreenheden (7) til muliggørelse af, at den indadrettede knop (21.3) afbøjes indad ved translation af hylsteret (12) i den distale retning (D) i forhold til bæreenheden (7) ved fjernelse af autoinjektoren (1) fra injektionsstedet.
10. Autoinjektor (1) ifølge et af ovennævnte krav, der er kendetegnet ved, at der er tilvejebragt en udløselig støj komponent (28), der er i stand til ved udløsning at frembringe et hørligt og/eller mærkbart feedback til en bruger, hvor støj komponenten (28) er indrettet til at blive udløst, når stemplet (9) når en position i forhold til sprøjten (3), hvor proppen (4) er placeret i nærheden af en proksimal ende af sprøjten (3), og hvor den udløste støj komponent (28) har indvirkning på en huskomponent (12, 13), der indikerer afslutning af injektionen.
11. Autoinjektor (1) ifølge krav 10, der er kendetegnet ved, at huskomponenten af autoinjektoren (1) omfatter mindst en del af chassiset (2) , hylsteret (12) , udløserknappen (13) , bæreenheden (7) og/eller stemplet (9).
12. Autoinjektor (1) ifølge et af kravene 3 til 11, der er kendetegnet ved, at der er tilvejebragt en visuel brugsindikator, der omfatter mindst ét indikatorvindue (32) i hylsteret (12), hvor en del af chassiset (2) er indrettet til at blive placeret bag indikatorvinduet (32), når hylsteret (12) er i dets distale position påvirket af kontrolfjederen (19), hvor en tap (20.4) på den første krave (20) er placeret udadrettet fra delen af chassiset (2), efter at den første krave (20) er blevet translateret i den proksimale retning (P) under kanyleindføring, hvor tappen (20.4) og delen af chassiset (2) fremviser et visuelt forskelligt træk.
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RU2607939C2 (ru) 2017-01-11
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SG192638A1 (en) 2013-09-30
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US9789255B2 (en) 2017-10-17
AU2012217084A1 (en) 2013-09-05
US20130317427A1 (en) 2013-11-28
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AU2012217084B2 (en) 2016-10-13
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WO2012110580A1 (en) 2012-08-23
EP2675503A1 (en) 2013-12-25

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