DK2564204T3 - Apparat til måling af immune- og oxygensystem og screening af lægemiddel - Google Patents
Apparat til måling af immune- og oxygensystem og screening af lægemiddel Download PDFInfo
- Publication number
- DK2564204T3 DK2564204T3 DK11777937.1T DK11777937T DK2564204T3 DK 2564204 T3 DK2564204 T3 DK 2564204T3 DK 11777937 T DK11777937 T DK 11777937T DK 2564204 T3 DK2564204 T3 DK 2564204T3
- Authority
- DK
- Denmark
- Prior art keywords
- rox
- box
- blood
- membrane
- stress
- Prior art date
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/84—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving inorganic compounds or pH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/22—Boron compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/15—Medicinal preparations ; Physical properties thereof, e.g. dissolubility
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/30—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indices; for individual health risk assessment
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16Z—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS, NOT OTHERWISE PROVIDED FOR
- G16Z99/00—Subject matter not provided for in other main groups of this subclass
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Urology & Nephrology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Inorganic Chemistry (AREA)
- Pathology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Databases & Information Systems (AREA)
- Data Mining & Analysis (AREA)
- Primary Health Care (AREA)
- Developmental Biology & Embryology (AREA)
- Virology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Claims (3)
1. Apparat til måling af ROX, BOX, ROXO2 og ROXNO i en blodprøve, hvilket apparat omfatter: en optisk probe, der bestemmer mængder for O2 og R0XO2 og en membran-baseret oxygenelektrode, som måler O2, NO, H2S og andre signalmaterialer, der er ubundne og således kan trænge gennem membranen, hvorved den nævnte membran-baserede oxygenelektrode og den optiske probe er operativt forbundet til en processor til beregning, over tid, af en værdi for BOX, som er en måling af et fald i mængden af O2, NO, H2S og andre signalmaterialer, der er ubundne og således kan trænge gennem membranen, i den nævnte prøve efter indføring af en første stress, af en værdi for ROX, som er en måling af en stigning i de nævnte mængder af
02, NO, H2S og andre signalmaterialer, der er ubundne og således kan trænge gennem membranen, efter indføring af en anden, forøget stress, af en værdi for ROXNO, som beregnes ved at bestemme en forskel mellem en stigning i den nævnte mængde af O2 målt ved den nævnte optiske probe og den nævnte stigning i de nævnte mængder af O2, NO, H2S og andre signalmaterialer, der er ubundne og således kan trænge gennem membranen, målt ved den nævnte membranen-baserede oxygenelektrode, og af en værdi for ROXO2, som er ROX minus ROXNO.
2. Apparatet ifølge krav 1, hvor den nævnte membranen-baserede oxygenelektrode er en polarografisk oxygenelektrode.
3. Apparatet ifølge krav 1, hvor den optiske probe er en fiber-optisk, lysemitte-rende diodeprobe, der er belagt med ruthenium.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32840910P | 2010-04-27 | 2010-04-27 | |
| PCT/US2011/034051 WO2011139733A2 (en) | 2010-04-27 | 2011-04-27 | Immune and oxygen system measuring and drug screening method and apparatus |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2564204T3 true DK2564204T3 (da) | 2017-05-08 |
Family
ID=44904347
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK11777937.1T DK2564204T3 (da) | 2010-04-27 | 2011-04-27 | Apparat til måling af immune- og oxygensystem og screening af lægemiddel |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US9140712B2 (da) |
| EP (1) | EP2564204B1 (da) |
| JP (2) | JP5698835B2 (da) |
| KR (1) | KR101332003B1 (da) |
| CN (1) | CN103003698B (da) |
| AU (1) | AU2011248644B2 (da) |
| BR (1) | BR112012027351B1 (da) |
| CA (1) | CA2797097C (da) |
| CO (1) | CO6640294A2 (da) |
| DK (1) | DK2564204T3 (da) |
| ES (1) | ES2611857T3 (da) |
| IL (1) | IL222603B (da) |
| MX (1) | MX336444B (da) |
| NZ (1) | NZ603749A (da) |
| PL (1) | PL2564204T3 (da) |
| PT (1) | PT2564204T (da) |
| RU (1) | RU2574000C2 (da) |
| SG (1) | SG185004A1 (da) |
| WO (1) | WO2011139733A2 (da) |
| ZA (1) | ZA201208847B (da) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10900954B2 (en) * | 2015-04-14 | 2021-01-26 | Blaze Medical Devices, Inc. | Method and system for inducing controlled and varied fluid stresses by bead oscillation |
| CN105823807B (zh) * | 2016-01-04 | 2018-04-20 | 浙江农林大学 | 抗癌药物羟喜树碱药效检测装置及检测方法 |
| KR20180107257A (ko) * | 2016-02-19 | 2018-10-01 | 난트 홀딩스 아이피, 엘엘씨 | 면역원 조절 방법 (methods of immunogenic modulation) |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4041933A (en) * | 1975-04-11 | 1977-08-16 | Siemens Aktiengesellschaft | Electrode for polarographic measurements in physiological media |
| SU1739295A1 (ru) | 1989-08-11 | 1992-06-07 | Ленинградский Государственный Институт Усовершенствования Врачей Им.С.М.Кирова | Способ определени стимулирующего действи фармпрепаратов на кислородсв зывающую функцию крови |
| WO1994004071A1 (en) * | 1992-08-19 | 1994-03-03 | Lynn Lawrence A | Apparatus for the diagnosis of sleep apnea |
| DE19612425C2 (de) * | 1995-03-31 | 2000-08-31 | Nihon Kohden Corp | Apparat zur Messung von Hämoglobinkonzentration |
| US5863460A (en) * | 1996-04-01 | 1999-01-26 | Chiron Diagnostics Corporation | Oxygen sensing membranes and methods of making same |
| US6532958B1 (en) * | 1997-07-25 | 2003-03-18 | Minnesota Innovative Technologies & Instruments Corporation | Automated control and conservation of supplemental respiratory oxygen |
| JP2001178817A (ja) * | 1999-12-24 | 2001-07-03 | Terumo Corp | 人工腎臓用装置およびこれを用いた品質評価装置ならびに流体回路 |
| US7025734B1 (en) * | 2001-09-28 | 2006-04-11 | Advanced Cardiovascular Systmes, Inc. | Guidewire with chemical sensing capabilities |
| AU2003276873A1 (en) * | 2002-09-10 | 2004-04-30 | Euro-Celtique, S.A. | Apparatus and method for non-invasive measurement of blood constituents |
| US6925852B2 (en) * | 2002-11-05 | 2005-08-09 | Kenneth Susko | Oxygen monitoring device |
| US20040133079A1 (en) * | 2003-01-02 | 2004-07-08 | Mazar Scott Thomas | System and method for predicting patient health within a patient management system |
| US7072804B2 (en) | 2004-09-28 | 2006-07-04 | Agilent Technologies, Inc. | Digital trigger filter for a real time digital oscilloscope |
| US20060171845A1 (en) * | 2005-01-31 | 2006-08-03 | Dakota Technologies, Inc. | Sensors for measuring analytes |
| US7504377B2 (en) * | 2006-10-23 | 2009-03-17 | Ikor, Inc. | Nitric oxide-blocked cross-linked tetrameric hemoglobin |
| AU2008279755B2 (en) * | 2007-07-26 | 2014-01-09 | Duke University | Measuring amount of bound and combined nitric oxide in blood |
-
2011
- 2011-04-27 PT PT117779371T patent/PT2564204T/pt unknown
- 2011-04-27 BR BR112012027351-5A patent/BR112012027351B1/pt active IP Right Grant
- 2011-04-27 MX MX2012012433A patent/MX336444B/es unknown
- 2011-04-27 PL PL11777937T patent/PL2564204T3/pl unknown
- 2011-04-27 US US13/695,150 patent/US9140712B2/en active Active
- 2011-04-27 CN CN201180032032.4A patent/CN103003698B/zh active Active
- 2011-04-27 SG SG2012078655A patent/SG185004A1/en unknown
- 2011-04-27 JP JP2013508185A patent/JP5698835B2/ja active Active
- 2011-04-27 NZ NZ60374911A patent/NZ603749A/en unknown
- 2011-04-27 KR KR1020127031086A patent/KR101332003B1/ko active IP Right Grant
- 2011-04-27 WO PCT/US2011/034051 patent/WO2011139733A2/en active Application Filing
- 2011-04-27 RU RU2012150435/15A patent/RU2574000C2/ru active
- 2011-04-27 DK DK11777937.1T patent/DK2564204T3/da active
- 2011-04-27 EP EP11777937.1A patent/EP2564204B1/en active Active
- 2011-04-27 AU AU2011248644A patent/AU2011248644B2/en active Active
- 2011-04-27 ES ES11777937.1T patent/ES2611857T3/es active Active
- 2011-04-27 CA CA2797097A patent/CA2797097C/en active Active
-
2012
- 2012-10-22 IL IL222603A patent/IL222603B/en active IP Right Grant
- 2012-11-22 ZA ZA2012/08847A patent/ZA201208847B/en unknown
- 2012-11-23 CO CO12212908A patent/CO6640294A2/es not_active Application Discontinuation
-
2014
- 2014-09-25 JP JP2014195088A patent/JP2015028490A/ja not_active Withdrawn
-
2015
- 2015-08-14 US US14/826,619 patent/US9811635B2/en active Active
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