DK250089A - Immunstimulerende 7-deaza-7-oxa- og 7-deaza-7-thia-analoge af 8-substituerede guanin-9-(1'-beta-d-aldoglycosidyl)-derivater samt deres anvendelse - Google Patents

Immunstimulerende 7-deaza-7-oxa- og 7-deaza-7-thia-analoge af 8-substituerede guanin-9-(1'-beta-d-aldoglycosidyl)-derivater samt deres anvendelse Download PDF

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Publication number
DK250089A
DK250089A DK250089A DK250089A DK250089A DK 250089 A DK250089 A DK 250089A DK 250089 A DK250089 A DK 250089A DK 250089 A DK250089 A DK 250089A DK 250089 A DK250089 A DK 250089A
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deaza
immunstimulating
aldoglycosidyl
oxa
beta
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DK250089A
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English (en)
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DK250089D0 (da
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Michael Goodman
Edward P Gamson
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Scripps Clinic Res
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Publication of DK250089D0 publication Critical patent/DK250089D0/da
Publication of DK250089A publication Critical patent/DK250089A/da

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/24—Heterocyclic radicals containing oxygen or sulfur as ring hetero atom

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK250089A 1988-05-24 1989-05-23 Immunstimulerende 7-deaza-7-oxa- og 7-deaza-7-thia-analoge af 8-substituerede guanin-9-(1'-beta-d-aldoglycosidyl)-derivater samt deres anvendelse DK250089A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/198,141 US5166141A (en) 1983-11-01 1988-05-24 Immunostimulating 7-deaza-7-oxa- and 7-deaza-7-oxo-analogs of 8-substituted-guanine-9-(1'-beta-D-aldoglycosidyl) derivatives and methods of treating test animals

Publications (2)

Publication Number Publication Date
DK250089D0 DK250089D0 (da) 1989-05-23
DK250089A true DK250089A (da) 1989-11-25

Family

ID=22732151

Family Applications (1)

Application Number Title Priority Date Filing Date
DK250089A DK250089A (da) 1988-05-24 1989-05-23 Immunstimulerende 7-deaza-7-oxa- og 7-deaza-7-thia-analoge af 8-substituerede guanin-9-(1'-beta-d-aldoglycosidyl)-derivater samt deres anvendelse

Country Status (7)

Country Link
US (1) US5166141A (da)
EP (1) EP0343945A3 (da)
JP (1) JPH0249789A (da)
AU (1) AU627178B2 (da)
DK (1) DK250089A (da)
IE (1) IE891673L (da)
PT (1) PT90638B (da)

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US5476659A (en) * 1982-11-09 1995-12-19 The Scripps Research Institute Cancerous B cell treatment using substituted nucleoside derivatives
US5041426A (en) * 1987-12-21 1991-08-20 Brigham Young University Immune system enhancing 3-β-d-ribofuranosylthiazolo[4,5-d]pyridimine nucleosides and nucleotides
US5994321A (en) * 1993-12-20 1999-11-30 Aronex Pharmaceuticals, Inc. Antiviral guanine analogs
US5446045A (en) * 1993-12-20 1995-08-29 Revankar; Ganapathi R. Antiviral guanine analogs
US5768154A (en) * 1996-04-08 1998-06-16 Asko, Inc. Method and apparatus for measuring the width of metal strip
US6509320B1 (en) * 1996-10-16 2003-01-21 Icn Pharmaceuticals, Inc. Purine L-nucleosides, analogs and uses thereof
CZ126799A3 (cs) * 1996-10-16 1999-07-14 Icn Pharmaceuticals Purinové L-nukleosidy a jejich analogy a farmaceutické prostředky, které je obsahují
EP1103559A1 (en) * 1997-01-17 2001-05-30 ICN Pharmaceuticals, Inc. Autoimmune nucleosides
US7638496B2 (en) 2000-02-15 2009-12-29 Valeant Pharmaceuticals North America Nucleoside analogs with carboxamidine modified monocyclic base
US7321033B2 (en) * 2001-11-27 2008-01-22 Anadys Pharmaceuticals, Inc. 3-B-D-ribofuranosylthiazolo [4,5-d] pyrimidine nucleosides and uses thereof
PT1824482E (pt) * 2004-12-17 2014-05-13 Anadys Pharmaceuticals Inc Compostos 3h-oxazolo e 3h-tiazolo[4,5-d]pirimidin-2-ona 3,5- -di-substituídos e 3,5,7-tri-substituídos e seus pró- -fármacos
SG152296A1 (en) 2005-11-21 2009-05-29 Anadys Pharmaceuticals Inc Novel process for the preparation of 5-amino-3h-thiazolo[4,5-d]pyrimidin-2- one
CA2655904C (en) * 2006-06-22 2014-11-18 Anadys Pharmaceuticals, Inc. Prodrugs of 5-amino-3-(3'-deoxy-.beta.-d-ribofuranosyl)-thiazolo[4,5-d]pyrimidin-2,7-dione
JP5225991B2 (ja) 2006-07-18 2013-07-03 アナディス ファーマシューティカルズ インク チアゾロ［４，５−ｄ］ピリミジンのカーボネート及びカルバメートプロドラッグ
US20110166092A1 (en) 2007-08-20 2011-07-07 Anadys Pharmaceuticals, Inc. Dosing methods for treating disease
RS61612B1 (sr) 2014-12-08 2021-04-29 Hoffmann La Roche 3-supstituisana 5-amino-6h-tiazolo[4,5-d]pirimidin-2,7-dion jedinjenja za lečenje i profilaksu virusne infekcije
KR20170113658A (ko) 2015-03-16 2017-10-12 에프. 호프만-라 로슈 아게 Tlr7 작용제 및 hbv 캡시드 조립 억제제를 사용하는 병용 치료
CN107743491B (zh) 2015-05-08 2020-08-21 豪夫迈·罗氏有限公司 用于治疗和预防病毒感染的新的氧硫杂环戊烷甲酸及其衍生物
CN107592864B (zh) 2015-05-12 2021-04-16 豪夫迈·罗氏有限公司 用于治疗和预防病毒感染的新的取代的氨基噻唑并嘧啶二酮
WO2017001307A1 (en) 2015-06-30 2017-01-05 F. Hoffmann-La Roche Ag Novel substituted aminothiazolopyrimidinedione for the treatment and prophylaxis of virus infection
BR112019013884A2 (pt) 2017-01-06 2020-03-03 F. Hoffmann-La Roche Ag Processo para a preparação de compostos de 5 -amino -6h´ -tiazolo [4,5 -d] pirimidina -2,7 -diona 3 -substituídos

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GB971700A (en) * 1961-02-02 1964-09-30 Boots Pure Drug Co Ltd Anti-Inflammatory Agents
AT290523B (de) * 1962-01-05 1971-06-11 Merck & Co Inc Verfahren zur Herstellung neuer α-(3-Indolyl)-carbonsäuren
FR4841M (da) * 1964-05-07 1967-02-20
US3313848A (en) * 1964-06-18 1967-04-11 Parke Davis & Co Anthranilic acids and derivatives
FR1546478A (fr) * 1967-01-27 1968-11-22 Rhone Poulenc Sa Nouveaux dérivés de l'acide benzoyl-3 phénylacétique et leur préparation
CH510660A (de) * 1967-09-11 1971-07-31 Ciba Geigy Ag Verfahren zur Herstellung neuer Glucofuranoside
DE1793336C3 (de) * 1967-09-11 1974-10-03 Ciba-Geigy Ag, Basel (Schweiz) D-Glucofuranoside, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Präparate
US3538077A (en) * 1967-09-26 1970-11-03 Ciba Geigy Corp D-glucofuranoside ether-esters
US3767805A (en) * 1968-03-27 1973-10-23 Ciba Geigy Corp Tertiary aminoacids in antiinflammatory compositions
US3600437A (en) * 1969-05-28 1971-08-17 Lilly Co Eli Substituted phenylalkanoic acids and derivatives thereof
US3654349A (en) * 1970-05-01 1972-04-04 Merck & Co Inc Substituted indenyl acetic acids
US3849572A (en) * 1970-09-15 1974-11-19 Merck & Co Inc Biphenyleneacetic acid anti-inflammatory agents
US3993755A (en) * 1973-04-09 1976-11-23 Valter Osvaldovich Kulbakh Pharmaceutical composition containing the N-methyl-d-glucosamine complex of 4-methyluracil and use thereof
US4486436A (en) * 1982-07-22 1984-12-04 Analgesic Associates Analgesic and anti-inflammatory compositions comprising caffeine and methods of using same
US4643992A (en) * 1982-11-09 1987-02-17 Scripps Clinic And Research Foundation Modulation of animal cellular responses with compositions containing 8-substituted guanine derivatives
US4746651A (en) * 1983-11-01 1988-05-24 Scripps Clinic And Research Foundation Antimicrobial chemotherapeutic potentiation using substituted nucleoside derivatives
US5041426A (en) * 1987-12-21 1991-08-20 Brigham Young University Immune system enhancing 3-β-d-ribofuranosylthiazolo[4,5-d]pyridimine nucleosides and nucleotides
US4880784A (en) * 1987-12-21 1989-11-14 Brigham Young University Antiviral methods utilizing ribofuranosylthiazolo[4,5-d]pyrimdine derivatives

Also Published As

Publication number Publication date
EP0343945A3 (en) 1991-05-15
EP0343945A2 (en) 1989-11-29
AU3481289A (en) 1989-11-30
IE891673L (en) 1989-11-24
AU627178B2 (en) 1992-08-20
DK250089D0 (da) 1989-05-23
US5166141A (en) 1992-11-24
PT90638B (pt) 1994-10-31
PT90638A (pt) 1989-11-30
JPH0249789A (ja) 1990-02-20

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