DK2303872T3 - Isoxazolderivater og deres anvendelse som metabotrope glutamatreceptorforstærkere - Google Patents

Isoxazolderivater og deres anvendelse som metabotrope glutamatreceptorforstærkere

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Publication number
DK2303872T3
DK2303872T3 DK09758630.9T DK09758630T DK2303872T3 DK 2303872 T3 DK2303872 T3 DK 2303872T3 DK 09758630 T DK09758630 T DK 09758630T DK 2303872 T3 DK2303872 T3 DK 2303872T3
Authority
DK
Denmark
Prior art keywords
metabotrop
amplifiers
glutamate receptor
isoxazole derivatives
isoxazole
Prior art date
Application number
DK09758630.9T
Other languages
Danish (da)
English (en)
Inventor
Joseph Cacciola
James Empfield
James Folmer
Angela M Hunter
Scott Throner
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of DK2303872T3 publication Critical patent/DK2303872T3/da

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/08—Wound clamps or clips, i.e. not or only partly penetrating the tissue ; Devices for bringing together the edges of a wound
    • A61B17/083—Clips, e.g. resilient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/08—Wound clamps or clips, i.e. not or only partly penetrating the tissue ; Devices for bringing together the edges of a wound
    • A61B17/085—Wound clamps or clips, i.e. not or only partly penetrating the tissue ; Devices for bringing together the edges of a wound with adhesive layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/10—Surgical instruments, devices or methods for applying or removing wound clamps, e.g. containing only one clamp or staple; Wound clamp magazines
    • A—HUMAN NECESSITIES
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    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/10—Surgical instruments, devices or methods for applying or removing wound clamps, e.g. containing only one clamp or staple; Wound clamp magazines
    • A61B17/105—Wound clamp magazines
    • A—HUMAN NECESSITIES
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    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
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    • A61P25/34—Tobacco-abuse
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    • A—HUMAN NECESSITIES
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    • A61P27/00—Drugs for disorders of the senses
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P7/10—Antioedematous agents; Diuretics
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    • A61P9/00—Drugs for disorders of the cardiovascular system
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Surgery (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Psychology (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Rheumatology (AREA)
  • Anesthesiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Otolaryngology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK09758630.9T 2008-06-06 2009-06-08 Isoxazolderivater og deres anvendelse som metabotrope glutamatreceptorforstærkere DK2303872T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5948508P 2008-06-06 2008-06-06
PCT/SE2009/050682 WO2009148403A1 (en) 2008-06-06 2009-06-08 Isoxazole derivatives and their use as metabotropic glutamate receptor potentiators

Publications (1)

Publication Number Publication Date
DK2303872T3 true DK2303872T3 (da) 2014-06-16

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DK09758630.9T DK2303872T3 (da) 2008-06-06 2009-06-08 Isoxazolderivater og deres anvendelse som metabotrope glutamatreceptorforstærkere

Country Status (40)

Country Link
US (4) US7790760B2 (enExample)
EP (2) EP2303872B1 (enExample)
JP (2) JP5476371B2 (enExample)
KR (1) KR20110020797A (enExample)
CN (1) CN102105466B (enExample)
AR (1) AR072016A1 (enExample)
AU (1) AU2009255784B2 (enExample)
BR (1) BRPI0913585A2 (enExample)
CA (1) CA2726925A1 (enExample)
CL (1) CL2010001348A1 (enExample)
CO (1) CO6321239A2 (enExample)
CR (1) CR11826A (enExample)
CU (1) CU23883B1 (enExample)
CY (1) CY1115301T1 (enExample)
DK (1) DK2303872T3 (enExample)
DO (1) DOP2010000375A (enExample)
EA (2) EA201300342A1 (enExample)
EC (1) ECSP10010662A (enExample)
ES (1) ES2469837T3 (enExample)
GT (1) GT201000342A (enExample)
HK (1) HK1201255A1 (enExample)
HN (1) HN2010002582A (enExample)
HR (1) HRP20140451T1 (enExample)
IL (1) IL209622A0 (enExample)
MX (1) MX2010012949A (enExample)
MY (1) MY156552A (enExample)
NI (3) NI201000209A (enExample)
NZ (1) NZ590344A (enExample)
PE (1) PE20110028A1 (enExample)
PL (1) PL2303872T3 (enExample)
PT (1) PT2303872E (enExample)
RS (1) RS53392B (enExample)
SA (1) SA109300358B1 (enExample)
SI (1) SI2303872T1 (enExample)
SV (1) SV2010003751A (enExample)
TW (3) TW201514173A (enExample)
UA (1) UA107649C2 (enExample)
UY (1) UY31870A (enExample)
WO (1) WO2009148403A1 (enExample)
ZA (1) ZA201008611B (enExample)

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JO3367B1 (ar) 2013-09-06 2019-03-13 Janssen Pharmaceutica Nv مركبات 2،1، 4- ثلاثي زولو [3،4-a] بيريدين واستخدامها بصفة منظمات تفارغية موجبة لمستقبلات ميجلور 2
CN109999025A (zh) 2014-01-21 2019-07-12 詹森药业有限公司 包括代谢型谷氨酸能受体亚型2的正别构调节物或正位激动剂的组合及其用途
IL279202B2 (en) 2014-01-21 2023-09-01 Janssen Pharmaceutica Nv Combinations containing positive allosteric modulators or orthosteric agonists of metabotropic glutamatergic subtype 2 receptor and their use
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