DK228984D0 - Benzoesyrederivater - Google Patents

Benzoesyrederivater

Info

Publication number
DK228984D0
DK228984D0 DK2289/84A DK228984A DK228984D0 DK 228984 D0 DK228984 D0 DK 228984D0 DK 2289/84 A DK2289/84 A DK 2289/84A DK 228984 A DK228984 A DK 228984A DK 228984 D0 DK228984 D0 DK 228984D0
Authority
DK
Denmark
Prior art keywords
benzoic acid
retarding
degradation
preventing
relates
Prior art date
Application number
DK2289/84A
Other languages
English (en)
Other versions
DK228984A (da
Inventor
Richard August Mueller
Richard Allen Partis
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Publication of DK228984D0 publication Critical patent/DK228984D0/da
Publication of DK228984A publication Critical patent/DK228984A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/10Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46Friedel-Crafts reactions
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/80Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
    • C07C49/807Ketones containing a keto group bound to a six-membered aromatic ring containing halogen all halogen atoms bound to the ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C63/00Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
    • C07C63/68Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings containing halogen
    • C07C63/70Monocarboxylic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C63/00Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
    • C07C63/68Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings containing halogen
    • C07C63/74Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings containing halogen having unsaturation outside the aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/01Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/32Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK228984A 1983-05-09 1984-05-08 Benzoesyrederivater DK228984A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/492,843 US4469885A (en) 1983-05-09 1983-05-09 Halogenated protease inhibitors

Publications (2)

Publication Number Publication Date
DK228984D0 true DK228984D0 (da) 1984-05-08
DK228984A DK228984A (da) 1984-11-10

Family

ID=23957852

Family Applications (1)

Application Number Title Priority Date Filing Date
DK228984A DK228984A (da) 1983-05-09 1984-05-08 Benzoesyrederivater

Country Status (12)

Country Link
US (1) US4469885A (da)
EP (1) EP0126372B1 (da)
JP (1) JPS59210046A (da)
AT (1) ATE20732T1 (da)
AU (2) AU571513B2 (da)
CA (2) CA1235426A (da)
DE (1) DE3460296D1 (da)
DK (1) DK228984A (da)
ES (1) ES8602589A1 (da)
IE (1) IE57394B1 (da)
NO (2) NO158378C (da)
ZA (1) ZA843451B (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4469885A (en) * 1983-05-09 1984-09-04 G. D. Searle & Co. Halogenated protease inhibitors
US4847202A (en) * 1983-05-09 1989-07-11 Georgia Tech Research Institute Heterocyclic inhibitors of serine proteases
US4501895A (en) * 1983-05-09 1985-02-26 G.D. Searle & Co. [Halo-4-(4,5-dihydro-4,4-dimethyl-2-oxazolyl)-phenyl]octadecan-ols and -ones
US4803294A (en) * 1987-10-29 1989-02-07 G. D. Searle & Co. Process and intermediates for the preparation of halogenated protease inhibitors
US4920120A (en) * 1988-01-25 1990-04-24 Warner-Lambert Company Antibacterial agents
US5238908A (en) * 1989-08-31 1993-08-24 Rohm And Haas Company Herbicidal glutaramic acids and derivatives
US5302752A (en) * 1989-10-30 1994-04-12 Ethyl Corporation Acetic acid derivatives and their production
US5086067A (en) * 1989-12-18 1992-02-04 G. D. Searle & Co. Ltb4 synthesis inhibitors
US5179123A (en) * 1989-12-18 1993-01-12 G. D. Searle & Co. LTB4 synthesis inhibitors
US5356919A (en) * 1991-05-30 1994-10-18 G. D. Searle & Co. Leukotriene B4 synthesis inhibitors
US5112864A (en) * 1991-05-30 1992-05-12 G. D. Searle & Co. PLA2 inhibitors as antiinflammatories
EP1674452A4 (en) * 2003-09-19 2007-10-10 Chugai Pharmaceutical Co Ltd NOVEL 4-PHENYLAMINO-BENZALDOXIME DERIVATIVE AND ITS USE AS MEK INHIBITOR
TWI361066B (en) 2004-07-26 2012-04-01 Chugai Pharmaceutical Co Ltd 5-substituted-2-phenylamino benzamides as mek inhibitors
ITMI20061365A1 (it) * 2006-07-13 2008-01-14 Dipharma Spa Procedimento per la preparazione di acidi boronici e loro derivati
CN111925289A (zh) * 2020-06-30 2020-11-13 浙江美诺华药物化学有限公司 一种5-溴-2-氯苯甲酸的制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1417412A1 (de) * 1958-05-22 1969-10-09 Tenneco Chem Pflanzenvernichtungsmittel
US3882180A (en) * 1969-10-08 1975-05-06 Merck & Co Inc Trifluoromethyl-substituted aromatic acids
US3661922A (en) * 1970-06-15 1972-05-09 Commercial Solvents Corp Process for purification of vinyl oxazolines
US3988471A (en) * 1973-07-05 1976-10-26 Chevron Research Company Insect control employing certain benzoates
US4092326A (en) * 1976-12-13 1978-05-30 Imc Chemical Group, Inc. Process for production of substituted oxazolines
EP0009699B1 (de) * 1978-09-30 1981-11-11 Bayer Ag Verfahren zur Herstellung weitgehend wasserfreier und Hydroxybenzoesäure-freier Alkalisalze von Hydroxybenzoesäureestern
US4469885A (en) * 1983-05-09 1984-09-04 G. D. Searle & Co. Halogenated protease inhibitors
NZ209209A (en) * 1983-08-29 1988-02-12 Sterling Drug Inc Substituted phenyl-aliphatic isoxazole derivatives and pharmaceutical compositions

Also Published As

Publication number Publication date
CA1252106A (en) 1989-04-04
NO158378C (no) 1988-08-31
NO165960C (no) 1991-05-15
IE841140L (en) 1984-11-09
EP0126372B1 (en) 1986-07-16
ZA843451B (en) 1985-06-26
JPS59210046A (ja) 1984-11-28
NO865194L (no) 1984-11-12
CA1235426A (en) 1988-04-19
DK228984A (da) 1984-11-10
AU590145B2 (en) 1989-10-26
NO165960B (no) 1991-01-28
AU1122288A (en) 1988-05-05
CA1252106C (da) 1989-04-04
ATE20732T1 (de) 1986-08-15
US4469885A (en) 1984-09-04
ES532343A0 (es) 1985-12-01
DE3460296D1 (en) 1986-08-21
EP0126372A1 (en) 1984-11-28
ES8602589A1 (es) 1985-12-01
NO841841L (no) 1984-11-12
IE57394B1 (en) 1992-08-26
AU2778584A (en) 1984-11-15
JPH0481577B2 (da) 1992-12-24
AU571513B2 (en) 1988-04-21
NO158378B (no) 1988-05-24

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment